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Lesions of the glutamatergic cortico-striatal projections in the rat ameliorate hypoglycemic brain damage in the striatum

Unilateral ablations of the motor cortex were performed on rats. One to two weeks following the ablation they were subjected to 30 min of reversible insulin-induced hypoglycemic coma. The levels of glutamate, aspartate, γ-aminobutyric acid (GABA), taurine, adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and phosphocreatine (PCr) were determined in frozen ti

The Opportunity Prior - A Proof-Based Prior for Criminal Cases

One of the greatest challenges to the use of probabilistic reasoning in the assessment of criminal evidence is the ‘problem of the prior’, i.e. the difficulty in establishing an acceptable prior probability of guilt. Even strong supporters of a Bayesian approach have often preferred to ignore priors and focus on the likelihood ratio (LR) of the evidence. But to calculate if the probability of guil

Leptin, Anxiety Symptoms, and Hypothalamic-Pituitary-Adrenal Axis Activity among Drug-Free, Female Suicide Attempters

BACKGROUND: Dysregulation of leptin secretion and functioning of the hypothalamic-pituitary-adrenal (HPA) axis may be involved in the pathophysiology of suicide. Preclinical and clinical studies have shown interactions between the HPA axis and leptin. There is also evidence for a negative relationship between leptin and anxiety in humans. However, these possible associations have not been studied

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In this short article, we describe the energy transition of the Danish island of Ærø to renewable energies.

Iceland Should Replace Its Central Bank with a Currency Board.

In this contribution, we discuss the menu of policy regimes available for Iceland. Each regime is evaluated against the characteristics of the Icelandic economy. We start with a short description of the Icelandic economy. We then examine the costs and benefts of alternative monetary regimes. We conclude that no regime Iceland has tried since attaining full sovereignty in 1918 has provided economicIn this contribution, we discuss the menu of policy regimes available for Iceland. Each regime is evaluated against the characteristics of the Icelandic economy. We start with a short description of the Icelandic economy. We then examine the costs and benefts of alternative monetary regimes. We conclude that no regime Iceland has tried since attaining full sovereignty in 1918 has provided economic

Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis–an external quality assessment workshop

Background and Objectives: Fetal RHD genotyping of cell-free fetal DNA from RhD-negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment workshop with the participation of 28 laboratories. Materials and Methods: Aliquots of pooled ma

Experiential Learning Theory as a Teaching Method in Climate Smart Architecture and Urban Design

This study focuses on the experiential learningtheory as an important teaching method for architecture andurban design students at architecture Dept., Lund University.By applying Kolb' s model - in a course so called ClimateSmart Architecture and Urban Design - , the diverse learningstyles of all learners are incorporated and a step by step coursedesign framework enables studio and seminar designi

The role of urban design in enhancing the microclimate and thermal comfort in warm-humid Dar es Salaam, Tanzania

Due to the complexity of the outdoor environment, urban design patterns considerably affect the microclimateand outdoor thermal comfort in a given urban morphology. Parameters such as building height and orientation,spaces between buildings, plot coverage, etc influence the microclimate in terms of solar access, shade, windspeed and direction. In warm-humid Dar es Salaam, the consideration of micr

How industry collaboration influences research: The case of the Swedish interdisciplinary materials consortia, 1990–2000

This article provides new insights into the consequences of university–industry collaboration for the content and conduct of academic research by analysing the Swedish research funding programme for the so-called ‘materials consortia’, in place between 1990 and 2000. Using secondary sources, the analysis highlights the causality in university–industry collaboration and the impact of such collabora

Updated European Consensus Statement on diagnosis and treatment of adult ADHD

Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD is currently underdiagnosed and undertreated in many European countries, leading to chronicity of symptoms and impairment, due to lack of, or ineffective treatment, and higher costs of illness. Methods The European Network A

Podocalyxin-like and rna-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer : A validatory study

Background: Urothelial bladder cancer (UBC) is a disease that often is discovered when the tumour is non-muscle invasive, i.e. in Ta or T1 stage. Some patients will progress into muscle-invasive disease, a potentially deadly condition. Although there are some prognostic models, the need for prognostic and predictive biomarkers is considerate and urgent. Membranous expression of podocalyxin-like pr