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Updated European Consensus Statement on diagnosis and treatment of adult ADHD

Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD is currently underdiagnosed and undertreated in many European countries, leading to chronicity of symptoms and impairment, due to lack of, or ineffective treatment, and higher costs of illness. Methods The European Network A

Podocalyxin-like and rna-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer : A validatory study

Background: Urothelial bladder cancer (UBC) is a disease that often is discovered when the tumour is non-muscle invasive, i.e. in Ta or T1 stage. Some patients will progress into muscle-invasive disease, a potentially deadly condition. Although there are some prognostic models, the need for prognostic and predictive biomarkers is considerate and urgent. Membranous expression of podocalyxin-like pr

Pop-up Mosques, Social Media Adhan, and the Making of Female and LGBTQ-Inclusive Imams

The last few decades have seen the appearance of a number of mosques that do not constitute buildings; they are mosques without bricks. This article therefore defines a new concept, the pop-up mosque, as an analytical term for the temporary conversion of an other-purposed space into a mosque, which is used for Islamic rituals such as Friday prayer and marriages. The pop-up mosque can produce relig

Under-five mortality and maternal HIV status in Tanzania: analysis of trends between 2003 and 2012 using AIDS Indicator Survey data

BackgroundMortality among children under five remains a significant health challenge across sub-Saharan Africa. HIV/AIDS is one of the leading contributors to the relatively slow decline in under-five mortality in this region. In Tanzania, HIV prevalence among under-five children is high and 90% of all infections are due to mother-to-child transmission.ObjectivesThe study aimed to examine the asso

Association Between Neighborhood Deprivation and Heart Failure Among Patients With Diabetes Mellitus : A 10-Year Follow-Up Study in Sweden

Background: Our aim was to study the potential effect of neighborhood deprivation on incident heart failure (HF) in patients with diabetes mellitus (DM). Methods: The study population included adults (n = 434,542) aged 30 years or older with DM followed from 2005 to 2015 in Sweden for incident HF. The association between neighborhood deprivation and the outcome was explored using Cox regression an

Divisible, Contingent and Parochial? : The instrumentality of EU fundamental rights

Human rights are meant to be universal, indivisible, and inalienable. They are legal norms that claim to reflect urgent moral concerns, and to protect human beings by mere virtue of their humanity. As such they are held to be universal, in that they apply to all human beings regardless of their background and nationality; they are inalienable, in that all human beings are born with them and they c

The host defense peptide LL-37 is internalized by human periodontal ligament cells and prevents LPS-induced MCP-1 production

Objective: The human host defense peptide LL-37 both shows antimicrobial effects and modulates host cell properties. Here, we assess the effects of synthesized LL-37 on lipopolysaccharide (LPS)-induced inflammation in human periodontal ligament (PDL) cells and investigates underlying mechanisms. Background: LL-37 has been detected in the periodontal tissues, but its functional importance for PDL c