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Global and domain-specific life satisfaction among older adults with long-term spinal cord injury

Objective: Although life expectancy after spinal cord injury (SCI) has increased, knowledge of life satisfaction and associated factors among older adults with long-term SCI is still very limited. The objective of this study was, therefore, to assess global and domain-specific life satisfaction among older adults with long-term SCI and investigate the association with sociodemographics, injury cha

International multi-institutional bench mark study on dosimetric and volumetric modulation using helical tomotherapy treatment planning for malignant pleural mesothelioma tumors

Determining the most desirable and achievable target dose and organ at risk (OAR) sparing using helical TomoTherapy planning system for mesothelioma treatment plans. A range of planning parameters was used. The reviewers’ ranking assessment (Ranking in Groups: 1 = Good, 2 = Above Average, 3 = Average, 4 = Poor).The overall rankings revealed that a plan with a balanced tradeoff among all planning o

Graphene-Based Metal-Free Catalysis

This chapter focuses on the use of doped carbon nanomaterials in catalysis. The availability of carbon nanotubes in the ‘90s and graphene about 10Â years later, prompted the development of fundamental research and novel nanotechnologies. We discuss this topic from a point of view that links fundamental surface science to the field of catalysis, in order to present the state of the art.

A Population-Based Comparison of the AJCC 7th and AJCC 8th Editions for Patients Diagnosed with Stage III Cutaneous Malignant Melanoma in Sweden

Background: Cutaneous melanoma is steadily increasing worldwide. The new AJCC 8th edition was recently launched and introduced several changes in melanoma staging, particularly for stage III. We conducted a population-based registry study with the purpose to evaluate the impact and prognostic accuracy of the new classification in Sweden. Methods: Consecutive patients diagnosed with stage III melan

Speech in 5-year-olds born with unilateral cleft lip and palate : a Prospective Swedish Intercenter Study

Studies on the impact of cleft palate surgery on speech with stringent methodology are called for, since we still do not know the best timing or the best method for surgery. The purpose was to report on speech outcome for all Swedish-speaking 5-year-olds born with a non-syndromic unilateral cleft lip and palate (UCLP), in 2008–2010, treated at Sweden’s six cleft palate centres, and to compare spee

A Colloid Approach to Self-Assembling Antibodies

Concentrated solutions of monoclonal antibodies have attracted considerable attention due to their importance in pharmaceutical formulations; yet, their tendency to aggregate and the resulting high viscosity pose considerable problems. Here we tackle this problem by a soft condensed matter physics approach, which combines a variety of experimental measurements with a patchy colloid model, amenable

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics

Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR) expression. Targeting proteins that are expressed as a down-stream effect of AR activity is a promising rationale for management of this disease. The hum