Research on climate change impact focuses on biophysical and economic dimensions. This paper seeks to unveil the association between smallholder farmers' food insecurity experience (FIE) during climate shock periods and their subsequent aspiration level. To this end, our analysis relied on data collected in rural Ethiopia following an unprecedented climate shock the country faced in 2016. We measu

A stochastic hierarchical model for the evolution of low grade gliomas is proposed. Starting with the description of cell motion using a piecewise diffusion Markov process (PDifMP) at the cellular level, we derive an equation for the density of the transition probability of this Markov process based on the generalised Fokker–Planck equation. Then, a macroscopic model is derived via parabolic limit

Background: Grade of non–muscle-invasive bladder cancer (NMIBC) is an important prognostic factor for progression. Currently, two World Health Organization (WHO) classification systems (WHO1973, categories: grade 1–3, and WHO2004 categories: papillary urothelial neoplasm of low malignant potential [PUNLMP], low-grade [LG], high-grade [HG] carcinoma) are used. Objective: To ask the European Associa

Background: Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal expansion of blood stem cells with leukemia-associated mutations—is a novel cardiovascular risk factor. Whether CHIP remains prognostic in individuals with established atherosclerotic cardiovascular disease (ASCVD) is less clear. Objectives: This study tested whether CHIP predicts adverse outcomes in individu

Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a transmembrane proteoglycan, is highly expressed in intestinal subtype gastric tumors and that this signature associates with patient poor survival. Further, we mechanistically demonstrate that SDC4 is a master regulator of gastric cancer cell motility and in

STUDY QUESTION: How does a history of cancer affect the likelihood of using assisted reproduction in order to achieve paternity? SUMMARY ANSWER: As compared to men with no history of cancer, use of assisted reproduction to achieve paternity was more frequent in fathers with a history of cancer, mainly those with testicular, prostate, and hematological and lymphatic malignancies. WHAT IS KNOWN ALRE

In recent years, battery energy storage systems (BESS) have gained prominence as a key technology enabling much needed electricity grid flexibility while simultaneously providing distinct value to its end-users. With the anticipated increase of residual value holding used batteries from mobility applications entering the market, more and more companies are looking to construct BESS offers around t

This master thesis invites the reader to acquire and examine new evidence about an emerging and growing sub-genre type of documentary film called Ayahuasca documentary. This study bases its definition of the Ayahuasca documentary sub-genre on a current work in the progress catalogue of over 50 documentary films, two of which were selected as case studies. These films suggest a growing cultural int

Through this research, I intend to investigate the fascinating domain of Ayahuasca documentary films. This emerging subgenre showcases explorers and scientists reconnecting with nature and spirituality, which I introduced to the reader through my explorative one-year master's thesis, A Study of Ayahuasca Documentary Film (2020). Furthermore, in the present study, I further my research by looki

Background: Current evidence suggests that use of intracoronary imaging during percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) reduces mortality. However, there is a scarcity of data on the overall role of intracoronary imaging, particularly in other non-LMCA proximal coronary artery lesions. We aimed to investigate the association of use of intracoronary imaging o

Amplification of the MYCN oncogene is found in ~20% of neuroblastoma (NB) cases and correlates with high-risk disease and poor prognosis. Despite the plethora of studies describing the role of MYCN in NB, the exact molecular mechanisms underlying MYCN’s contribution to high-risk disease are not completely understood. Herein, we implemented an integrative approach combining publicly available RNA-S

Biological aerosol particles affect human health, are essential for microbial and gene dispersal, and have been proposed as important agents for atmospheric processes. However, the abundance and size distributions of atmospheric biological particles are largely unknown. In this study we used a laser-induced fluorescence instrument to measure fluorescent biological aerosol particle (FBAP) concentra

Rationale: Allergic asthma is linked to impaired bronchial epithelial secretion of IFNs, which may be causally linked to the increased risk of viral exacerbations. We have previously shown that allergen immunotherapy (AIT) effectively reduces asthma exacerbations and prevents respiratory infections requiring antibiotics; however, whether AIT alters antiviral immunity is still unknown. Objectives:

Across the world are small local agencies connected to the United Nations. Unlike the larger bureaucratic organs that make up the UN, these smaller specialized agencies do not work to frame the founding ideals of the UN which are decided on at the highest levels within the institution, but to interpret, carry out, and monitor different mandates or programs at the local level. These agencies transl

Access to safe drinking water and sanitation is a given standard and considered as basic human rights in urban areas and industrialized countries. However, 40 % of the world's population living in rural areas in developing countries lack access to safe drinking water. Many ongoing projects are focused on providing safe drinking water and sanitation in rural areas, including Hamro Paani. Hamro