We explore the potential of ultimate unification of the Standard Model matter and gauge sectors into a single (Formula presented.) superfield in ten dimensions via an intermediate Pati–Salam gauge theory. Through a consistent realisation of a (Formula presented.) orbifolding procedure and renormalisation group evolution of gauge couplings, we establish several novel benchmark scenarios for New Phy

OBJECTIVE: The aim of this study was to describe and present the outcomes of a specific treatment protocol for aortic vascular graft and endograft infections (VGEIs) without explantation of the infected graft.METHODS: This was a retrospective, observational single centre cohort study carried out between 2012 and 2022 at a tertiary hospital. An aortic VGEI was defined according to the Management of

The international UN Climate Change conferences known as “Conferences of the Parties (COPs)” have an enormous convening power and are attended annually by tens of thousands of actors working on climate change topics from a wide range of perspectives. In the COP spaces outside of the formal negotiations, the communication culture is dominated by “side events,” a format that relies heavily on conven

Aims: To determine the ophthalmological outcome at 6.5 years of age in children treated for retinopathy of prematurity (ROP), and registered in the national Swedish National Register for ROP register. Methods: Data on ROP, treatment and ophthalmological outcome were retrieved from the register. Visual acuity (VA), refractive errors and strabismus, together with visual impairment (VI) and any signi

To cope with global climate change, chlorofluorocarbons and hydrofluorocarbons refrigerants have been or will be abandoned by different countries worldwide. Natural refrigerants seem to be promising substitutes in the near future. In this study, eco-friendly refrigerants R290 and R170 are adopted as high-temperature and low-temperature fluid in a cascade refrigeration freezer to generate −80°C. Th

This study presents the results of a set of large-scale fire tests performed on horizontal polyurethane foam slabs. Slab thickness, ignition location, and environment (free burn or corner wall) were varied over 23 individual tests. In a continuation of a previous study by the authors, four different slab thicknesses, five different ignition locations, and three environmental modification combinati

The emergence of a monkeypox (MPOX) outbreak in 2022 represented the most recent recognizable public health emergency at a global level. Improving knowledge and attitude towards MPOX, particularly among healthcare workers (HCWs), can be a valuable approach in public health preventive efforts aiming to halt MPOX virus spread. The aim of the current study was to evaluate the knowledge and attitude o

Assessing the status of water resources is essential for long-term planning related to water and many other needs of a country. According to climate reports, climate change is on the rise in all parts of the world; however, this phenomenon will have more consequences in arid and semi-arid regions. The aim of this study is to evaluate the effects of climate change on groundwater, surface water, and

Sustainable practices are increasingly promoted in the restaurant industry. One significant aspect of sustainability in restaurants is the use of local supply chains, especially for food, which also serve as a means for restaurants to promote freshness of produce, sourcing, and quality. Considering the prevalence of locality in menu marketing, this study aims to explore the relationships between s

Flimmer kan være irriterende, men frem for alt kan det have en negativ effekt på menneskers sundhed, og forårsage irritation, hovedpine, overanstrengelse af øjne og migræne. Med introduktionen af LED baserede lyskilder og lamper er flimmer igen blevet et problem. Udover denne unødvendige lidelse, som flimmer kan bevirke hos enkeltpersoner, skaber de negative konsekvenser en hindring for bred og hu

Flimmer, eller nærmere bestemt tidslig lys modulation (TLM), er igen blevet et problem i forbindelse med indførelse af LED-basret belysningsteknologi. TLM, dvs. variationer i lysintensiteten over tid, kan have negativ effekt på menneskers sundhed, og forårsage irritation, hovedpine, overanstrengelse af øjne og migræne. Udover denne unødvendige lidelse, som flimmer kan bevirke hos enkeltpersoner, s

Bizarre parosteal osteochondromatous proliferation (BPOP) (Nora lesion) is a benign bone surface lesion, which most commonly occurs in the digits of young patients and has a high rate of recurrence. Histologically, it is composed of a mixture of disorganized bone, cartilage, and spindle cells in variable proportions and characterized by amorphous "blue bone" mineralization. Recurrent chromosomal a

Pancreas-derived islet amyloid polypeptide (IAPP) crosses the blood–brain barrier and co-deposits with amyloid beta (Aβ) in brains of type 2 diabetes (T2D) and Alzheimer’s disease (AD) patients. Depositions might be related to the circulating IAPP levels, but it warrants further investigation. Autoantibodies recognizing toxic IAPP oligomers (IAPPO) but not monomers (IAPPM) or fibrils have been fou

Multidrug-resistant tuberculosis (MDR) continues to pose a threat to public health. Previously, we identified a cationic host defense peptide with activity against Mycobacterium tuberculosis in vivo and with a bactericidal effect against MDR M. tuberculosis at therapeutic concentrations. To understand the mechanisms of this peptide, we investigated its interactions with live M. tuberculosis and li

Introduction: The current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak. Materials and methods: The data came from the larger COMET-G study. The study sample includes 12,792 health professionals from 40 countries (62.40% women aged 39.76 ± 11.70; 36.81% men aged 35.91 ± 11.00 and 0.78% no

The presence of CD169+ macrophages in the draining lymph nodes of cancer patients is, for unknown reasons, associated with a beneficial prognosis. We here investigated the prognostic impact of tumor-infiltrating CD169+ macrophages in primary tumors (PTs) and their spatial relation to tumor-infiltrating B and T cells. Using two breast cancer patient cohorts, we show that CD169+ macrophages were spa

Healthcare workers (HCWs) were the first population group offered coronavirus disease 2019 (COVID-19) vaccines in South Africa because they were considered to be at higher risk of infection and required protecting as they were a critical resource to the health system. In some contexts, vaccine uptake among HCWs has been slow, with several studies citing persistent concerns about vaccine safety and

When individuals self-select (or are selected) into a study based on factors that influence the outcome, conclusions may not generalize to the full population. To compensate for this, results may be adjusted, for example, by standardization on the set of common causes of participation and outcome. Although such standardization is useful in some contexts, the common causes of participation and outc

UppdragArbetet med kunskapssammanställningen definierades av Myndigheten förarbetsmiljökunskap till att omfatta den psykosociala arbetsmiljöns inverkanpå den seniora arbetskraften1 i en svensk kontext, det vill säga effekten påindividen utifrån den mentala arbetsmiljö och den arbetssociala miljö somhen befinner sig i. Dock samvarierar olika faktorer i individers arbetssitua-tion. För att fånga in This report from the Swedish Agency for Work Environment Knowledge isconcerned with the impact of the psychosocial work environment — that is,the mental work environment and social work environment — on the seniorworkforce (≥55 years of age) in a Swedish context. However, many differentfactors can affect an individual’s work situation. Therefore, the studies inclu-ded in this literature review hav