Introduction. Type 2 diabetes (T2D) is the most common type of diabetes, and it can cause complications such as diabetic kidney disease (DKD), the main cause of end-stage renal disease worldwide. There is an urgent need to develop new biomarkers that would improve DKD’s risk prediction in patients with T2D. This research aimed at identifying novel epigenetic biomarkers associated with future DKD i

Poststructuralist perspectives need to be reconciled with political economic readings of urban globalization. One approach complements the other: the enactment of distantiated circuits and the territorialization of flows occur within existing geographies of uneven development while contingently reproducing or reshaping such spatial conditions of possibility. We argue that broadening the realm of c

Background: Anterior resection (AR) is considered the gold standard for curative cancer treatment in the middle and upper rectum. The goal of the sphincter-preserving procedure, such as AR, is vulnerable to anastomotic leak (AL) complications. Defunctioning stoma (DS) became the protective measure against AL. Often a defunctioning loop-ileostomy is used, which is associated with substantial morbid

Cesium manganese chloride (CsMnCl3) nanocrystals (NCs) have recently been recognized as potential lead-free perovskite candidates for red emission. To ascertain how the luminescence properties depend on the NC structures formed under different synthesis conditions, we synthesized CsMnCl3NCs in two polymorphic structures, namely, cubic (c-CsMnCl3) and rhombohedral (r-CsMnCl3), by tuning the reactio

Hemodynamic assessment is an integral part of the diagnosis and management of cardiovascular disease. Four-dimensional cardiovascular magnetic resonance flow imaging (4D Flow CMR) allows comprehensive and accurate assessment of flow in a single acquisition. This consensus paper is an update from the 2015 ‘4D Flow CMR Consensus Statement’. We elaborate on 4D Flow CMR sequence options and imaging co

Most neoplasia-associated gene fusions are formed through the fusion of the 5′-part of one gene with the 3′-part of another. We here describe a unique mechanism, by which a part of the KMT2A gene through an insertion replaces part of the YAP1 gene. The resulting YAP1::KMT2A::YAP1 (YKY) fusion was verified by RT-PCR in three cases of sarcoma morphologically resembling sclerosing epithelioid fibrosa

Knee joint functional deficits are common after anterior cruciate ligament (ACL) injury, but different assessment methods of joint function seem to provide contradicting information complicating recovery monitoring. We previously reported improved perceived knee function and functional performance (forward lunge ground contact time) in patients with an ACL injury from pre to 10 months post ACL rec

BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.METHOD: Seventy-six patients (bone-, cardiac-

Background: There is a lack of objective dynamic knee joint control measures that can be related to the status of the anterior cruciate ligament (ACL). The purpose of this study was to introduce two novel measures and apply a third to determine how dynamic knee joint control changes in relation to ACL status during dynamic movements. Methods: Twenty patients (13 male) were tested pre- (ACLd) and 1

We investigated the effects of including kinematic constraints in the analysis of knee kinematics from skin markers and compared the result to simultaneously recorded trajectories of bone pin markers during gait of six healthy subjects. The constraint equations that were considered for the knee were spherical and revolute joints, which have been frequently used in musculoskeletal modelling. In the

We investigated the accuracy of a linear soft tissue artefact (STA) model in human movement analysis. Simultaneously recorded bone-mounted pin and skin marker data for the thigh and shank during walking, cutting and hopping were used to measure and model the motion of the skin marker clusters within anatomical reference frames (ARFs). This linear model allows skin marker movements relative to the

In this work we use the method of eigenfamilies to construct explicit complex-valued proper p-harmonic functions on the compact real Grassmannians. We also find proper p-harmonic functions on the real flag manifolds which do not descend onto any of the real Grassmannians

Designing a hole-transport material (HTM) that guarantees effective hole transport while self-assembling at the perovskite|HTM interface with the formation of an ordered interlayer, has recently emerged as a promising strategy for high-performance and stable perovskite solar cells (PSCs). Hydrogen bonding (HB) is a versatile multi-functional tool for the design of small molecular HTMs. However, to

We study how inheriting parents' credit histories affects the initial credit scores, access to credit, and life cycle borrowing of young individuals entering the credit market. We establish that inherited histories significantly positively affect initial scores, which in turn are very persistent. Inherited histories only affect outcomes through initial credit scores, which then have significant pe

Progressive habitat fragmentation threatens plant species with narrow habitat requirements. While local environmental conditions define population growth rates and recruitment success at the patch level, dispersal is critical for population viability at the landscape scale. Identifying the dynamics of plant meta-populations is often confounded by the uncertainty about soil-stored population compar

The ongoing Internet of Things revolution has led to strong demand for low-cost, ubiquitous light sensing based on easy-to-fabricate, self-powered photodetectors. While solution-processable lead-halide perovskites have raised significant hopes in this regard, toxicity concerns have prompted the search for safer, lead-free perovskite-inspired materials (PIMs) with similar optoelectronic potential.

This article explores how football players and scouts in Sweden narrate their stories of transfers within the Swedish football system. This article presents first-person narrations as male players as well as scouts from elite clubs were interviewed in connection to transfer patters to, from and within Sweden. The aim is to analyse how the transfer system takes shape in stories presented by scouts

Introduction Knee muscles are commonly labeled as flexors or extensors and aptly stabilize the knee against sagittal plane loads. However, how these muscles stabilize the knee against adduction-abduction and rotational loads remains unclear. Our study sought 1) to classify muscle roles as they relate to joint stability by quantifying the relationship between individual muscle activation patterns a