A study was performed to verify the effect of ciprofloxacin on the production of interleukin-2 and other cytokines in cultures of human peripheral lymphocytes. In the presence of ciprofloxacin, lymphocytes demonstrated increased synthesis of interleukin-2 (100-fold, 7-fold and 1.5-fold increase at ciprofloxacin concentrations of 80, 20 and 5 μg/ml respectively), as measured by radioimmunoassay. Sy

Foscarnet has been shown to inhibit the proliferation of human T and B lymphocytes in vitro. The production of lymphokines was more strongly affected than the DNA synthesis. Monocyte function was only partly inhibited by the highest foscarnet concentration tried. The influence of foscarnet on the immune system could explain the beneficial effect observed in patients with HBV-related fulminant hepa

Molecular dynamics simulations of nano-sized beams with square cross sections of single-crystal Cu, solid as well as holding defects and loaded in displacement controlled tension until rupture have been performed. The defects are either edge crack-like or through-the-thickness voids. Three different cross section sizes and two different crystallographic orientations have been investigated. As expe

With the elimination of Soviet state communism in the early 1990s, the ideational foundation of politics in the five Central Asian former Soviet republics had to undergo fundamental rebuilding. Instead of the defunct basis of Soviet-style Marxism-Leninism, the rulers of the suddenly independent Central Asian states urgently had to identify other ways and means of legitimizing their hold on power.

This paper discusses static stability of a planar object grasped by multifingers with three joints. Each individual joint (prismatic joint or revolute joint) is modeled as a linear spring stiffness. The object mass and the link masses are also included. We consider not only pure rolling contact but also frictionless sliding contact. The grasp stability is investigated using the potential energy me

This thesis contributes to empirical research in labor economics. It consists of three self-contained papers.The first paper, The Effect of Paid Vacation on Health: Evidence from Sweden, analyzes the causal effect of paid vacation on health. Using register data on the universe of central government employees in Sweden, I exploit an age-based rule stipulated in the collective agreement covering the

Epidemiological contact tracing complemented with genotyping of clinical Mycobacterium tuberculosis isolates is important for understanding disease transmission. In Sweden, tuberculosis (TB) is mostly reported in migrant and homeless where epidemiologic contact tracing could pose a problem. This study compared epidemiologic linking with genotyping in a low burden country. Mycobacterium tuberculosi

Background Breathlessness is prevalent in the general population and may be associated with adverse health outcomes. This study aimed to evaluate the association of breathlessness with Chronic Obstructive Pulmonary Disease (COPD) events, cardiac events and all-cause mortality from middle-age throughout life. Methods Breathlessness was measured in 699, 55-year old men residing in Malmö, Sweden usin

Arabidopsis thaliana L. is a small flowering plant that is widely used as a model organism in plant biology. In the present study, we study the peripheral membrane protein ATEXPA23 from Arabidopsis thaliana L. using homology modelling and molecular docking. The microarray analysis shows expression of ATEXPA23 (AT5G39280) protein, which leads to loosening and extension of plant cell walls. This pro

Många medarbetare och chefer i offentlig sektor vittnar om hur detaljstyrning, överdriven formbundenhet och felriktad mätning hindrar dem från att göra ett gott arbete. De upplever att verksamheten styrs och leds med fjärrkontroll och med bristande lyhördhet för behoven längst ut i styrkedjan. Forskningen pekar i samma riktning. Det här leder inte bara till minskad motivation och arbetsglädje, uta

This paper explores the urban form, demographic and socio-economic dependencies of walking, cycling and e-biking in Beijing based on a survey (N = 1427) of daily travel among residents in eight neighborhoods, enriched with urban form variables. The results show that walking is most frequently used, followed by cycling, which in turn is more frequent than e-biking. Walking and cycling are preferred

Controlled experiments on software variants enable e-commerce companies to increase sales by providing user-adapted functionality. Our goal is to understand how the context of experimentation influences tool support. We performed a case study at Apptus that develops algorithms for e-commerce. We investigated how the case company uses experiments through five semi-structured interviews. We identifi

On the evening of 6 December 1933, members of the National Socialist Party of Sweden (SNSP, Sveriges Nationalsocialistiska Parti), at this time the most aggressive Nazi organisation in the country, violently attacked a lecture at Stockholm University. This gave rise to an extensive press debate; newspapers from left to right condemned the attack, which ended up being a propaganda fiasco for SNSP.

With the increasing focus on reducing emissions and making fuel efficient vehicles within the automotive industry over the past few years, new methods are constantly being investigated to improve the efficiency of the powertrain. One such method is recovering waste heat from the exhaust gases as well as the coolant using a thermodynamic cycle such as a Rankine cycle. However, most studies looking With the increasing focus on reducing emissions and making fuel efficient vehicles within the automotive industry over the past few years, new methods are constantly being investigated to improve the efficiency of the powertrain. One such method is recovering waste heat from the exhaust gases as well as the coolant using a thermodynamic cycle such as a Rankine cycle. However, most studies looking

Gravitational instabilities play an important role in galaxy evolution and in shaping the interstellar medium (ISM). The ISM is observed to be highly turbulent, meaning that observables like the gas surface density and velocity dispersion depend on the size of the region over which they are measured. In this work, we investigate, using simulations of Milky Way-like disc galaxies with a resolution