Organotin compounds are highly toxic environmental pollutants with neurotoxic and endocrine-disrupting effects. They are potent inhibitors of glutathione transferases (GSTs), thus impeding their detoxication and antioxidant functions. Several GSTs, including equine GST A3-3 (EcaGST A3-3), exhibit steroid double-bond isomerase activity and are involved in the biosynthesis of testosterone and proges

Hermeneutik, vetenskapen om tolkning, förknippar vi kanske vanligen med textstudier, men begreppet har kommit att få en vidare betydelse inom fenomenologin genom filosoferna Heidegger och Gadamer på ett sätt som är relevant för det psykoterapeutiska arbetet. Syftet med denna essä är att fördjupa diskussionen om dialektiken mellan det tolkande jaget och den andre, och spegla den mot en psykoterapeu

The cross-layer approach presented in this article involves co-designing a feedback controller’s parameters together with the schedule of an Ethernet network used for communicating state information and control signals. The temporal properties of an Ethernet network depend significantly on the schedules and routes of the data flows along switches. Researchers have studied various design-space expl

I argue that given a plausible reading of John Williams’s Stoner (2012 [1965]) the novel throws light on the demands and costs of pursuing a strategy for self-realisation along Platonic lines which seeks unification through the adoption of a single exclusive end in a manner that emulates the Socratic maieutic teacher. The novel does not explicitly argue either for or against such a strategy but ra

Almost thirty years ago the criteria that are currently used to verify claims for the discovery of a new element were set down by the comprehensive work of a Transfermium Working Group, TWG, jointly established by IUPAC and IUPAP. The recent completion of the naming of the 118 elements in the first seven periods of the Periodic Table of the Elements was considered as an opportunity for a review of

Background: Low levels of the soluble tumour necrosis factor-like weak inducer of apoptosis (sTWEAK) and depression are linked to cardiovascular disease. Galectin-3, inadequate glycemic control and low high-density lipoprotein (HDL)-cholesterol levels were previously linked to depression in these patients with type 1 diabetes mellitus (T1DM). The main aim was to explore whether sTWEAK was associat

The purpose of this study was to compare complication rates at the mandibulotomy site between patients receiving preoperative radiotherapy (RT) and those receiving postoperative RT during treatment for oral and oropharyngeal cancer where the surgical procedure required a mandibular osteotomy to gain access to the tumour. Sixty-four consecutive patients treated during the period 2000–2015 were avai

We study extensions of the classical SIR model of epidemic spread. First, we consider a single population modified SIR epidemics model in which the contact rate is allowed to be an arbitrary function of the fraction of susceptible and infected individuals. This allows one to model either the reaction of individuals to the information about the spread of the disease or the result of government rest

We undertake a fundamental study of network equilibria modeled as solutions of fixed-point equations for monotone linear functions with saturation nonlinearities. The considered model extends one originally proposed to study systemic risk in networks of financial institutions interconnected by mutual obligations. It is one of the simplest continuous models accounting for shock propagation phenomen

Arctic observing and data systems have been widely recognized as critical infrastructures to support decision making and understanding across sectors in the Arctic and globally. Yet due to broad and persistent issues related to coordination, deployment infrastructure and technology gaps, the Arctic remains among the most poorly observed regions on the planet from the standpoint of conventional obs

Ecological diversity among diurnal birds of prey, or raptors, is highlighted regarding their sensory abilities. While raptors are believed to forage primarily using sight, the sensory demands of scavengers and predators differ, as reflected in their visual systems. Here, I have reviewed the visual specialisations of predatory and scavenging diurnal raptors, focusing on (1) the anatomy of the eye a

Spin electronic devices based on crystalline oxide layers with nanoscale thicknesses involve complex structural and magnetic phenomena, including magnetic domains and the coupling of the magnetism to elastic and plastic crystallographic distortion. The magnetism of buried nanoscale layers has a substantial impact on spincaloritronic devices incorporating garnets and other oxides exhibiting the spi

Communicating results from genomic sequencing to family members can play an essential role allowing access to surveillance, prevention, treatment or prophylactic measures. Yet, many patients struggle with communication of these results and it is unclear to what extent this is discussed during the consent process. We conducted an online systematic search and used content analysis to explore how con

Background: Evidence is lacking on the differences between hospitalisation of people with dementia living in nursing homes and those living in the community. The objectives of this study were: 1) to describe the frequency of hospital admission among people with dementia in eight European countries living in nursing homes or in the community, 2) to examine the factors associated with hospitalisatio

The Northern high latitudes are warming twice as fast as the global average, and permafrost has become vulnerable to thaw. Changes to the environment during thaw leads to shifts in microbial communities and their associated functions, such as greenhouse gas emissions. Understanding the ecological processes that structure the identity and abundance (i.e., assembly) of pre- and post-thaw communitiesThe Northern high latitudes are warming twice as fast as the global average, and permafrost has become vulnerable to thaw. Changes to the environment during thaw leads to shifts in microbial communities and their associated functions, such as greenhouse gas emissions. Understanding the ecological processes that structure the identity and abundance (i.e., assembly) of pre- and post-thaw communities

Atmospheric inversions have been used for the past two decades to derive large-scale constraints on the sources and sinks of CO2 into the atmosphere. The development of dense in situ surface observation networks, such as ICOS in Europe, enables in theory inversions at a resolution close to the country scale in Europe. This has led to the development of many regional inversion systems capable of as