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Summary: The existing information supports the use of this material as described in this safety assessment. Propyl propionate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that propyl propionate is not genotoxic. Data on propyl propionate provide a
α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has several physiologically relevant properties, including binding of heme and radicals as well as enzymatic reduction, that are used in the protection of cells and tissue. Research has revealed that A1M can ameliorate heme and ROS-induced injuries in cell cultures, organs, explants and animal models. Recently, i
Cephalopods have very conspicuous eyes that are often compared to fish eyes. However, in contrast to many fish, the eyes of cephalopods possess mobile pupils. To increase the knowledge of pupillary and thus visual function in cephalopods, the dynamics of the pupil of one of the model species among cephalopods, the common octopus (Octopus vulgaris), was determined in this study. We measured pupilla
A non-destructive testing system requires multiple system configuration parameters during the operation process. For a given transducer, scanning frequency and number of measurements for averaging are just among those parameters. This work tests the central limit theorem to optimally set these parameters. The authors have designed a compact ultrasound computer tomography scanner from scratch just
Active matter exhibits various forms of nonequilibrium states in the absence of external forcing, including macroscopic steady-state currents. Such states are often too complex to be modeled from first principles, and our understanding of their physics relies heavily on minimal models. These are mostly studied in the case of "dry"active matter, where particle dynamics are dominated by friction wit
Background: Targeted surveillance of at-risk individuals in families with increased risk of hereditary cancer is an effective prevention strategy if relatives are identified, informed and enrolled in screening programs. Despite the potential benefits, many eligible at-risk relatives remain uninformed of their cancer risk. This study describes the general public's opinion on disclosure of hereditar
Multifocal plane microscopy allows for capturing images at different focal planes simultaneously. Using a proprietary prism which splits the emitted light into paths of different lengths, images at 8 different focal depths were obtained, covering a volume of 50x50x4 μm3. The position of single emitters was retrieved using a phasor-based approach across the different imaging planes, with better tha
The research area of climate field reconstructions has developed strongly during the past 20 years, motivated by the need to understand the complex dynamics of the earth system in a changing climate. Climate field reconstructions aim to build a consistent gridded climate reconstruction of different variables, often from a range of climate proxies, using either statistical tools or a climate model
This paper revisites the direct synthesis tuning method of continuous-time low-order controllers, and specially PID controllers, for control of time-delayed single-input single-output processes. A setpoint prefilter is included to improve the servo response and integrating load disturbances are accounted for. Robustness is addressed by the feedback controller to obtain the desired maximum sensitiv
Although the use of location-based data (location coupled with semantic information) within Geographical Information Systems (GIS) and from Earth Observation (e.g. satellite) sources has been long established for decision makers, this has only recently been reflected in the construction sector with a more recent move from Computer Aided Design (CAD) to Building Information Modelling. BIM has opene
Neuro-electronic interfaces, which can be used for stable communication between neurons-computers over long periods of time, would be valuable for understanding and interacting with the nervous system. A major challenge has been to overcome the tissue reactions towards implanted electrodes. Flexible microelectrodes that cause less implantation injury and which can follow the micromotions of the br
PurposeSleep apnea syndrome (SAS) is a relatively common disorder, but many patients with SAS are still undiagnosed. Using Japanese annual health check and medical claims data, we analyzed the association between hemoglobin upswing, defined as an increase in hemoglobin level within the reference range, and the incidence of SAS.MethodsIn this study, we used the Japan Medical Database Center (JMDC)
The Papuan language Kalamang has an adnominal demonstrativeopa, which marksreferents that are cognitively accessible either because they are common ground orbecause they are previously mentioned in the discourse. It is mainly an endophoricdemonstrative which has tracking and recognitional uses, but it can be used ex-ophorically as well. It can be used for both maintaining and reintroducing refer-e
Social media companies have resorted to censorship to suppress misinformation about the COVID-19 pandemic. This is not the most prudent solution though given the uncertainties about the disease.
