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Industrial applications of ultrafiltration in pharmaceutical biotechnology

Ultrafiltration with diafiltration is a state-of-the-art process used to separate solutions containing high and low molecular weight solutes. The focus of this paper is on the different concepts of ultrafiltration with diafiltration - batch, continuous and counter-current - and the potential realization of diafiltration on an industrial scale in pharmaceutical biotechnology. Two case studies will

Food & bev : anyone for a tasty beverage?

Taste is the most important criteria in evaluating the quality of wine and beer. Alfa Laval's Frank Lipnizki, Carl-Erik Nielsen, Robert Betcke and Jose Caprio highlight the potential that membrane processes offer in maintaining and improving taste during production.

Closing the loops in the pulp and paper industry with membrance technology

Membrane technology is a relative new technology in the pulp and paper industry with interesting applications in the water loop, the by-product loop and the chemical loop. The technology was pioneered in the pulp and paper industry by DDS Filtration, now Alfa Laval Nakskov in the 1970'ies and this article reviews the opportunities to use membrane technology in the different loops investigated over

Differences in glycemic control across world regions : A post-hoc analysis in patients with type 2 diabetes mellitus on dual antidiabetes drug therapy

Objective:This post-hoc analysis of the EDGE (Effectiveness of Diabetes control with vildaGliptin and vildagliptin/mEtformin) study assessed inter-regional differences in baseline characteristics and response to treatment intensification with dual oral antidiabetes drugs (OADs) in patients with type 2 diabetes mellitus (T2DM).Methods:Patients with T2DM inadequately controlled with first-line monot

Repeated nationwide point-prevalence surveys of antimicrobial use in Swedish hospitals : Data for actions 2003-2010

This study sought to analyse antimicrobial pressure, indications for treatment, and compliance with treatment recommendations and to identify possible problem areas where inappropriate use could be improved through interventions by the network of the local Swedish Strategic Programme Against Antibiotic Resistance (Strama) groups. Five point-prevalence surveys were performed in between 49 and 72 pa

Spatial Differentiation in Industrial Dynamics. The Case of the Netherlands (1994–2005)

We compare the industrial dynamics in the core, semi-periphery and periphery in the Netherlands in terms of firm entry-exit, size, growth and location patterns. The contribution of our work is to provide the first comprehensive study on spatial differentiation in industrial dynamics for all firm sizes and all sectors, including services. We find that location patterns are largely consistent with t

Psychic Changes following Myelography with Metrizamide and Iohexol : A comparative investigation with psychologic tests

Based upon the results of repeated psychologic tests, psychic impairment following myelography has been studied in 60 patients. Thirty of these had lumbar myelography with metrizamide and 30 with iohexol. Psychic impairment was noted in both groups, although with a higher frequency and much more marked in the group which had metrizamide myelography. For this type of examination iohexol is thus to

Exploring the impact of regional climate and local hydrology on Pinus sylvestris L. growth variability – A comparison between pine populations growing on peat soils and mineral soils in Lithuania

Aims: To compare growth variability of Scots pine (Pinus sylvestris L.) on different soil types, and to assess the potential of peat-soil pines for climatological and hydrological studies.Methods: We used extensive dendrochronological anal- yses to investigate temporal and spatial responses of pines growing on peat soils and mineral soils in three regions of Lithuania.Results: Significant correlatAimsTo compare growth variability of Scots pine (Pinus sylvestris L.) on different soil types, and to assess the potential of peat-soil pines for climatological and hydrological studies.MethodsWe used extensive dendrochronological analyses to investigate temporal and spatial responses of pines growing on peat soils and mineral soils in three regions of Lithuania.ResultsSignificant correlations wer

Lower spatial QRS-T angle rules out sustained ventricular arrhythmias in children with hypertrophic cardiomyopathy

Introduction: The spatial peaks QRS-T angle accurately distinguishes children with hypertrophic cardiomyopathy from their healthy counterparts. The spatial peaks QRS-T angle is also useful in risk stratification for ventricular arrhythmias. We hypothesised that the spatial peaks QRS-T angle would be useful for the prediction of ventricular arrhythmias in hypertrophic cardiomyopathy patients under

Thermo-economic study on the implementation of steam turbine concepts for flexible operation on a direct steam generation solar tower power plant

Among concentrating solar power technologies, direct steam generation solar tower power plants represent a promising option. These systems eliminate the usage of heat transfer fluids allowing for the power block to be run at greater operating temperatures and therefore further increasing the thermal efficiency of the power cycle. On the other hand, the current state of the art of these systems doe

Schottky barrier and contact resistance of InSb nanowire field-effect transistors

Understanding of the electrical contact properties of semiconductor nanowire (NW) field-effect transistors (FETs) plays a crucial role in the use of semiconducting NWs as building blocks for future nanoelectronic devices and in the study of fundamental physics problems. Here, we report on a study of the contact properties of Ti/Au, a widely used contact metal combination, when contacting individua

Design and analysis of a reflector antenna system based on doubly curved Circular Polarization Selective Surfaces

This paper discusses the design and analysis of a reflector antenna system combining two doubly-curved Circular Polarization Selective Surfaces to provide a functionality equivalent to that of a dual gridded reflector but in circular polarization. The key feature of this design is to use a non-resonant CPSS design to avoid the bandwidth limitation of most CPSS designs previously discussed in the l

Origin of B-cell neoplasms in autoimmune disease

Autoimmune diseases (ADs) are associated with a number of B-cell neoplasms but the associations are selective in regard to the type of neoplasm and the conferred risks are variable. So far no mechanistic bases for these differential associations have been demonstrated. We speculate that developmental origin of B-cells might propose a mechanistic rationale for their carcinogenic response to autoimm

Does Eligibility for Tertiary Education Affect Crime Rates? Quasi-Experimental Evidence

Objectives: This paper estimates the effect of tertiary education eligibility on crime in Sweden. The hypothesis tested is that continuing to higher education decreases crime rates since it allows young people to escape inactivity and idleness, which are known to trigger crime. However, to qualify for tertiary education, individuals have to meet the eligibility requirements in upper-secondary scho