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Den unge lejonhanne som röt men aldrig flög : Om ett israeliskt stridsflygplan och de lärdomar det kan förmedla till Gripen

Anmälan av boken "Lavi. The United States, Israel, and a Controversial Fighter Jet" av John W Golan (Lincoln NE: Potomac Books | University of Nebraska Press, 2016; ISBN 978-1-61234-722-6)Review of the book entitled "Lavi. The United States, Israel, and a Controversial Fighter Jet" by John W. Golan (Lincoln NE: Potomac Books | University of Nebraska Press, 2016; ISBN 978-1-61234-722-6)

The health returns of attending university for the marginally eligible student

A key policy question is whether continued expansion of university education is beneficial for the marginally eligible student. In this paper we exploit an arbitrary university eligibility rule combined with regression discontinuity design to estimate the causal effect of university attendance on healthcare utilization amongst young adults in Sweden. We find that the eligibility rule leads to a cl

Window of Opportunities : The Great Depression, Protectionism and the Rise of Profitable Settler Agriculture in Africa

The establishment of profitable European settler agriculture overseas has received considerable scholarly attention. Much of this literature focus on the ‘New World’ and the European off-shoots. It is generally argued that the golden age of these settler societies were 1870 to 1913. A globalization wave gave the settler farmers access to migrant labour and global markets. By contrast, Europeansett

Polyhydroxyalkanoate synthase (PhaC) : The key enzyme for biopolyester synthesis

Polyhydroxyalkanoates (PHAs) are considered good candidates in replacing commercial petrochemical plastics in certain applications like single-use packaging since they are biodegradable, biocompatible and share similar properties with conventional plastics. PHA synthase (PhaC) is the key enzyme in PHA biosynthesis. There are four classes of PhaC, namely, class I, class II, class III and class IV,

The Mitochondrial Epigenome : An Unexplored Avenue to Explain Unexplained Myopathies?

Mutations in either mitochondrial DNA (mtDNA) or nuclear genes that encode mitochondrial proteins may lead to dysfunctional mitochondria, giving rise to mitochondrial diseases. Some mitochondrial myopathies, however, present without a known underlying cause. Interestingly, methylation of mtDNA has been associated with various clinical pathologies. The present study set out to assess whether mtDNA

Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization

Therapeutic strategies directed at the tumor surfaceome (TS), including checkpoint inhibitor blocking antibodies, antibody drug conjugates (ADCs), and chimeric antigen receptor T (CAR-T) cells, provide a new armament to fight cancer. However, a remaining bottleneck is the lack of strategies to comprehensively interrogate patient tumors for potential TS targets. Here, we have developed a platform (

Long-Read Sequencing Reveals Genetic Adaptation of Bartonella Adhesin A Among Different Bartonella henselae Isolates

Bartonella henselae is the causative agent of cat scratch disease and other clinical entities such as endocarditis and bacillary angiomatosis. The life cycle of this pathogen, with alternating host conditions, drives evolutionary and host-specific adaptations. Human, feline, and laboratory adapted B. henselae isolates often display genomic and phenotypic differences that are related to the express

Train Passes and Dwell Time Delays

Traffic on railways is increasing and this makes train traffic to be highly interconnected . This paper investigates how passing of train affects dwell time delays in Sweden. Three scenarios are considered by combining the scheduled and actual operations: passes that happened as scheduled, unscheduled passes that happened in operations, and scheduled passes that were cancelled. A logistic regressi

Passenger flows and dwell times for commuter trains in Stockholm

This study investigates how the volume and flow of passengers affect dwell times, usingdata from commuter trains in Stockholm. We show that dwell times often take longer thanscheduled and that most station stops involve rather limited numbers of passengers.Improving the performance at these stops with small volumes can thus have a sizeableimpact on the overall on-time performance. We find a quadraThis study investigates how the volume and flow of passengers affect dwell times, using data from commuter trains in Stockholm. We show that dwell times often take longer than scheduled and that most station stops involve rather limited numbers of passengers. Improving the performance at these stops with small volumes can thus have a sizeable impact on the overall on-time performance. We find a qu

Hospitalisations with infectious disease diagnoses in somatic healthcare between 1998 and 2019 : A nationwide, register-based study in Swedish adults

Background: Several studies indicate increasing hospitalisation rates for specific infectious diseases (IDs). Studies describing the entire ID spectrum are scarcer. Our aim was to describe hospital use with ID diagnoses in Swedish adults from 1998 to 2019. Methods: All four-position codes in ICD-10 were reclassified as ID or non-ID diagnoses. Using data from the National Patient Register, age-stan

Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids

Human cholangiocyte organoids are promising for regenerative medicine applications, such as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor-derived basement membrane extracts (BME), which is poorly defined, highly variable and limits the direct clinical applications of organoids in patients. Extracellular matrix (ECM)-derived hydrogels prepared from decellula