The Role of Vhl in T cell mediated control of Mtb infection
Development of a successful prophylactic or therapeutic treatment for active Tuberculosis (TB) has been hampered by the bacilli’s ability to evade, tolerate, subvert host immunity and persist in a hypoxic intracellular niche. Upon infection with M. tuberculosis (Mtb), there is an increased demand for metabolites by cells to respond to the robust immune activation, which is met with a shift of meta
