Att bygga material av proteiner är en konst som våra kroppar är specialister på. Men när vi medvetet försöker designa proteinmaterial, så blir det tydligt hur komplexa och svårstyrda biofysikens lagar är. Det här examensarbetet har som mål att lägga grunden för ett proteinmaterial som kan skapas eller dissociera som respons på förändrad Ca2+-koncentration. Om ett sådant material kan framställas meTo build materials of proteins is an art that nature is a specialists in. But when we actively try to design protein materials, it becomes clear how complex and hard to control the biophysical world is. This master thesis aims to lay the foundation for a protein material that forms and dissociates as a response to changed Ca2+ concentration. If such a material is to be produced with an ordered str

The project’s focus is on the protein galectin-8N and crystallizing it with lactose and a novel ligand, MH1. The question for the project comes from previous work that shows that galectin-8N has an empty pocket on the surface of the protein. A novel ligand was designed to improve the affinity to the protein through potential interactions between the chlorophenyl group in the ligand and a pocket on

This essay examines the typographic discussions in Sweden around the turn of the 20th century. The focus lies on Gothenburg-based printer Waldemar Zachrisson, a driving force in these matters. The starting-point of the study is the industrialization of the printing in the 19th century, when printing changed from being a craft to being a largely mechanical process. Several voices from the turn of t

Alzheimer’s disease (AD) is characterized by amyloid-β (Aβ) and tau depositions as well as neurodegeneration, and is typically accompanied by a progressive decline in episodic memory. Previous research proposes two neural memory networks that process different stimulus domains. Specifically, a posterior-medial (PM) and an anterior-lateral (AL) network handle scene- and object-specific information,

Research on dark matter has been ongoing for almost a century. Findings show that dark matter makes up 27% of the universe’s density and thus it is a crucial component of understanding how the universe came about. This thesis describes the key pieces of evidence for the existence of dark matter and its properties. An emphasis is put on the effects of dark matter on processes in the early universe.

This thesis describes the process and the approach taken to determine the current limitations and potential improvements of the GPX Porosity prototype. To continue the development of the GPX Porosity instrument, a series of comparative measurements has been performed on pharmaceutical ribbons, to understand better what are the factors limiting the optical porosity measurement precision and if oth

Shabestar basin in the East Azerbaijan province, Northwest Iran, where irrigation is the main groundwater consumer, has experienced large-scale subsidence and groundwater deletion, which poses a threat to the local agricultural activities, economic development, and food security. With the emergency of mitigating the risk, satisfying future demand for groundwater, and improving resilience consideri

Syfte: Syftet är i denna studie att undersöka hur svensk dags- och kvällspress konstruerar läsarens uppfattning om ungdomsbrottslingar som blivit misstänkta för eller har begått ett narkotikabrott. Syftet är vidare att se vilken eller vilka olika diskurser som synliggörs i de olika nyhetsartiklar som blir publicerade av svensk dags- eller kvällspress. Teori: I denna uppsats är Laclau och Mouffe´s

Introduction: Validation of a new test method to determine nicotine from chewing gum extracts with ultra high-performance liquid chromatography. Background: In Quality Control-laboratories, the methods that are regularly used are consistently developed in order to conduct effective analysis procedures. The aim of all of these developments is to simplify the analysis as much as possible and make t

Background: Previous study found that 2 batches of Nopal flour supplied by the same suppliers at different time was performing different results in in vitro studies and the quality of Nopal flour might thus be different. Besides, investigation on whether the soluble or the insoluble fraction of the Nopal flour suspensions contributed to the glycemic modulation was still necessary. Method: Compo

There are over 1.1 million small- or medium-sized enterprises (SMEs) in Sweden. But even if they have a significant impact on both the country’s economy as well as creating a majority of all Swedish jobs, the current research within competence development has in large, overlooked SMEs. The purpose of this study is therefore to fill that gap by investigating current practices and facilitation of co

I denna uppsats har jag undersökt den litteräre arketypen jurodivyj eller ”dåre för Kristi skull” och hur denna har utvecklats i den ryska litteraturen. Jag har kommit fram till att karaktärstypen kan porträtteras väldigt annorlunda från hur verklighetens exempel på heliga dårar har framställts i de hagiografiska helgonberättelserna. De underliggande skälen till denna utveckling går att hitta hos In this thesis, I have examined the literary archetype of the yurodivy or “fool for Christ’s sake” and how it has developed within Russian literature. I find that the character may be portrayed significantly different from the real-life yurodivy depicted in the hagiographic tales. The roots for this development are mainly found in Fyodor Dostoevsky, who constructed what is called the “stylized hol

Hur lantbruket kan bidra till omställningen mot en 100% förnybar elproduktion. Skiftet från fossil till förnybar energi är centralt i kampen mot klockan för att begränsa den globala uppvärmningen. Ett av målen för Sveriges långsiktiga energipolitik är att elproduktionen ska vara 100% förnybar år 2040. Lantbrukare har stora tak- och markarealer som skulle kunna nyttjas i högre grad än de gör idag As part of a sustainable energy system, Sweden has declared a target of 100 % renewable electricity production by 2040. Farmers have the potential to further this process and simultaneously contribute to a decentralized energy system. This study aims to identify drivers and barriers for the adoption of solar and wind energy production in the agricultural sector. Furthermore, it examines how policy

The increasingly rapid urbanization has led to vast impervious surface areas in the urban environment. This situation of impervious surfaces has increased the surface temperature and interrupted the natural water circle, which has negatively impacted the urban environment. Human activities' continuous greenhouse gas emission has contributed to global climate change, which has caused some atmos

District heating is a common means of space and hot water heating in Sweden. However, the demand for heating is not the same at all times. On a yearly basis more heat is required during winter, while next to none is needed in summer. Since the demand for heat load varies throughout the year, when trying to predict it, using a model that changes with the seasons can give a more accurate prediction.

It is commonly assumed that algorithmic curation of search results creates filter bubbles, where users’ beliefs are continually reinforced and opposing views are suppressed. However, empirical evidence has failed to support this hypothesis. Instead, we suggest that filter bubbles may result from individuals acting selectively on information made available by search engines. When presented with sea

Government and individual responses to the coronavirus disease 2019 (COVID-19) pandemic have had significant health and economic consequences. Governments imposed measures, including lockdowns, designed to suppress transmission and alleviate the burden on health systems, while private individuals exercised voluntary social distancing, compliance with government-imposed measures and exhibited incre

Purpose: This study aims to add and extend onto the existing studies regarding open innovation in SMEs but to tackle it from a neglected angle that is operating during times of uncertainty. Additionally, this study seeks to explore the mechanisms which SMEs use to reduce R&D budgets, increase the quality of innovations and continue the pace of innovations during the COVID-19 pandemic. Methodo