INTRODUCTION: Temporal lobe epilepsy is the most common form of focal epilepsy, often associated with cognitive impairments, particularly in memory functions, and depression. Sex and APOE ε4 genotype play a crucial role in modulating cognitive outcomes and depression in various neurological conditions like Alzheimer's disease. However, the combined effects of APOE genotype and sex on cognitive per

Peritoneal dialysis (PD) is a cost-effective, home-based kidney replacement therapy that enhances patient autonomy. Nevertheless, the clinical use of PD is limited by chronic fluid overload and excessive glucose absorption, which can lead to complications, such as cardiovascular disease, metabolic disturbances, and deterioration of the peritoneal membrane.The aims of this thesis were to examine gl

Introduction: The complement and kallikrein-kinin systems (KKS) are both activated during vascular inflammation, and there are many known interactions between the two systems. This study investigated if KKS activation induced complement activation on endothelial cells, and if activation was dependent on bradykinin B1 receptor (B1R) signaling.Methods: KKS was activated in normal human serum by kaol

Bakgrund: Tidigare forskning har visat att kreativa aktiviteter som körsång kan ha hälsofrämjande effekt fysiskt, psykiskt och socialt. Det finns en kunskapslucka i arbetsterapeutisk forskning kring upplevelsen av körsång som kreativ metod. Det är relevant att utforska körmedlemmars upplevelser av aktiviteten för att utforska hur den bidrar till välbefinnande. Syfte: Undersöka körsångares upplevelBackground: Prior research has shown that creative activities like choir singing can have physical, psychological and social health benefits. There is a knowledge gap in occupational therapy about the experiences of choir signing as a creative activity. It is relevant to explore experiences of the activity and how it contributes to well-being. Aim: Explore choir singers' experience of choir th

Almost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through familiAlmost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through famili

Accurately representing and predicting hydrological processes in terrestrial ecosystems is crucial for understanding the impacts of global environmental change, particularly climate change. This doctoral thesis aims to advance the understanding of vegetation-hydrology interactions and provides new modelling approaches to enhance hydrological prediction abilities. The thesis is grounded in the eval

There is a high demand to design and develop recyclable biobased polymers using eco-friendly synthetic approaches. In this work, we present the facile synthesis of two dicarboxylate monomers with a central non-cyclic acetal unit (dimethyl 4,4'(methylenebis(oxy))dibenzoate and dimethyl 4,4'-(methylenebis(oxy))bis(3-methoxybenzoate)), using potentially biosourced methyl paraben and methyl vanillate.

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Amyloids are elongated supramolecular protein self-assemblies. Their formation is a non-covalent assembly process and as such is fully reversible. Amyloid formation is associated with several neurodegenerative diseases, and the reversibility is key to maintaining the healthy state. Reversibility is also key to the performance of fibril-based biomaterials and functional amyloids. The reversibility

Spectrum imaging with energy-dispersive X-ray spectroscopy (EDS) has become ubiquitous in material characterization using electron microscopy. Multivariate statistical methods, commonly principal component analysis (PCA), are often used to aid analysis of the resulting multidimensional datasets; PCA can provide denoising prior to further analysis or grouping of pixels into distinct phases with sim

There are different ways to bring a cypress tree to mind. We might think about atree, speak about it, or imagine it. The cypress might come to us unbidden inmemory, or in dream. But we might also see a cypress tree, or feel its branches inour hands. This way of bringing the tree to mind is distinctive because the treeitself seems to be present in our experience. Our experience has perceptualpresen