Published 14 January 2021 Cluster analyses were performed to group variables with close proximity and to obtain homogenous clusters of individuals (n = 22,057) in the Malmö Preventive Project (MPP) cohort. Variables clustered included obesity, kidney dysfunction, diabetes mellitus (DM), hypertension, cardiovascular disease (CVD), dyslipidemia, pulmonary dysfunction (PD), smoking, and the use of di

https://www.lupop.lu.se/article/absolute-risk-gout-clusters-gout-associated-comorbidities-and-lifestyle-factors-30-years-follow - 2025-04-23

Published 15 January 2021 Maldescended testes or cryptorchidism is a genital birth defect that affects 2–9% of all male new-borns. Over the last 40 years there have been reports of increased prevalence in countries like the US, the UK and the Scandinavian countries. This possible increase has in some studies been linked to a foetal exposure to chemical pollutants. In this matched casecontrol study

https://www.lupop.lu.se/article/exposure-polychlorinated-compounds-and-cryptorchidism-nested-case-control-study - 2025-04-23

Published 15 January 2021 COVID-19 and lockdown strategies may affect mental health and addictive behavior differently in the population, and elite athletes are among the professions clearly affected by the pandemic. This study in top elite athletes aimed to study current perceived psychological influence from COVID-19 and symptoms of depression, anxiety and changes in alcohol drinking, gambling b

https://www.lupop.lu.se/article/psychological-distress-and-problem-gambling-elite-athletes-during-covid-19-restrictions-web-survey - 2025-04-23

Published 16 January 2021 Maldescended testes or cryptorchidism is a genital birth defect that affects 2–9% of all male new-borns. Over the last 40 years there have been reports of increased prevalence in countries like the US, the UK and the Scandinavian countries. This possible increase has in some studies been linked to a foetal exposure to chemical pollutants. In this matched casecontrol study

https://www.lupop.lu.se/article/exposure-polychlorinated-compounds-and-cryptorchidism-nested-case-control-study-0 - 2025-04-23

Published 16 January 2021 The obesity epidemic has influenced pain rehabilitation clinics. To date, little is known about baseline level of physical activity (PA) in patients referred to pain rehabilitation clinics. We aimed to investigate the PA levels of patients referred to pain rehabilitation clinics and to evaluate the effect of excess weight on PA level. Read more at Facing obesity in pain r

https://www.lupop.lu.se/article/facing-obesity-pain-rehabilitation-clinics-profiles-physical-activity-patients-chronic-pain-and - 2025-04-23

Published 17 January 2021 Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients.

https://www.lupop.lu.se/article/familial-associations-between-autoimmune-hepatitis-and-primary-biliary-cholangitis-and-other - 2025-04-23

Published 17 January 2021 The study population included a random sample of 2656 men (45.7%) and 3159 (54.3%) women from the longitudinal national studies' "Good Aging in Skåne" (GÅS) and SNAC-B, both part of the Swedish National Study on Aging and Care (SNAC). Data on Neugartens Life Satisfaction Index-A (LSI-A), medical history, activities of daily life (ADL) and socio-demographics were collected

https://www.lupop.lu.se/article/life-satisfaction-index-lsi-normative-data-general-swedish-population-aged-60-93-years - 2025-04-23

Published 15 January 2021 Öppna utlysningar: Bidrag till kliniska studier inom behandlingsforskning - skissansökan / Bidrag till investering i befintlig forskningsinfrastruktur / Internationell postdok inom medicin och hälsa (vårens utlysning) / Internationell postdok inom naturvetenskap och teknikvetenskap (vårens utlysning) / Internationell postdok inom humaniora och samhällsvetenskap inklusive

https://www.lupop.lu.se/article/vrs-utlysningsar-2021-ar-nu-igang - 2025-04-23

Published 5 April 2018 It is now much easier for researchers to make use of SND’s web services. The first step is an improved service for the submission of research data for description and reuse. The next step will simplify the process of ordering data from SND. Read more here.

https://www.lupop.lu.se/article/snd-launches-improved-web-service-researchers - 2025-04-23

Published 18 January 2021 Att forskningsresultat ska kunna upprepas är en av vetenskapens grundläggande principer. Ändå visar flera genomgångar av vetenskapliga studier att det inte ser ut så. Kritiker pekar på flera orsaker och nu vill forskare minska fokus på publiceringshetsen för att minska felaktigheter. Hör mer på https://sverigesradio.se/artikel/7647634.

https://www.lupop.lu.se/article/problem-i-forskarvarlden-manga-forskningsresultat-kan-inte-upprepas - 2025-04-23

Published 18 January 2021 Traumatic brain injury (TBI) is a major cause of disabilities and mortality worldwide, with higher prevalence in offender populations than in the general population. Previous research has strongly advocated increased awareness of TBI in offender populations. The aim of this study was to explore the prevalence and characteristics of TBI, and to investigate associations and

https://www.lupop.lu.se/article/exploring-traumatic-brain-injuries-and-aggressive-antisocial-behaviors-young-male-violent-offenders - 2025-04-23

Published 18 January 2021 The Kingdom of Crystal, an area in southern Sweden famous for its many glassworks, is historically heavily burdened by pollution from this industry. Glass crust containing cadmium (Cd), lead (Pb), and arsenic (As) has been deposited around the area and used as filling. The purpose of this study was to monitor whether the high levels of metals in the contaminated soil were

https://www.lupop.lu.se/article/cadmium-and-lead-levels-blood-and-arsenic-levels-urine-among-schoolchildren-living-contaminated - 2025-04-23

Published 19 January 2021 It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level of circulating inflammatory proteins and that chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how added sugar and SSB intake associate with 136 measured plasma proteins and C-reactive protein (CRP) in the Malmö Diet and Ca

https://www.lupop.lu.se/article/identification-inflammatory-and-disease-associated-plasma-proteins-associate-intake-added-sugar-and - 2025-04-23

Published 19 January 2021 With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [granulomatosis with polyangiitis (GPA), microscopic polyangiitis, and eosinophilic GPA] diagnosed between 1997 and 2010 were assessed. The patients were followed until death or December 31, 2015. The age- and sex-standardized incidence ratios (SIR) were estimated using t

https://www.lupop.lu.se/article/malignancies-patients-antineutrophil-cytoplasmic-antibody-associated-vasculitis-population-based - 2025-04-23

Published 20 January 2021 Data were obtained from the prospective, longitudinal, population‐based Children of Western Sweden cohort, which focused on children born in 2003. The parents answered questionnaires at six months and one, four, eight and 12 years of age. Personal identity numbers linked 3634 children to the Swedish Prescribed Drug Register (SPDR) and the National Patient Register (NPR).

https://www.lupop.lu.se/article/parental-questionnaires-provided-reliable-data-childhood-asthma-compared-national-registers - 2025-04-23

Published 20 January 2021 Quality in medical research has recently been criticized for being low, especially in observational research. Methodology is increasingly difficult, but collaboration between clinical researchers and biostatisticians may improve research and reporting quality. The aim of this study is to quantify the value of a biostatistician in the team of authors. Read more at Is repor

https://www.lupop.lu.se/article/reporting-quality-medical-publications-associated-biostatisticians-co-authors-registered-report - 2025-04-23

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 8 June 2021 This study extends TCAL by disentangling causes of death contributions. The strength of the approach is that it allows identification of mortality differences in cohorts with members still alive, as well as identification of which ages and causes of death contribute to mortality differentials between populations. R

https://www.lupop.lu.se/article/reflection-modern-methods-cause-death-decomposition-cohort-survival-comparisons - 2025-04-23

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 9 June 2021 Advances in synthetic control methods bring new opportunities to conduct rigorous research in evaluating public health interventions. However, incorporating synthetic controls in interrupted time series studies may not always nullify important threats to validity nor improve causal inference. Read the paper at http

https://www.lupop.lu.se/article/can-synthetic-controls-improve-causal-inference-interrupted-time-series-evaluations-public-health - 2025-04-23

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 10 June 2021 Concerns have been expressed over standards of statistical interpretation. Results with P <0.05 are often referred to as ‘significant’ which, in plain English, implies important. This leads some people directly into the misconception that this provides proof that associations are clinically relevant. Read the pape

https://www.lupop.lu.se/article/reflection-modern-methods-statistics-education-beyond-significance-novel-plain-english - 2025-04-23

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 17 June 2021 Standard errors are usually calculated based on assumptions underpinning the statistical model used in the estimation. However, there are situations in which some assumptions of the statistical model including the variance or covariance of the outcome across observations are violated, which leads to biased standar

https://www.lupop.lu.se/article/reflection-modern-methods-demystifying-robust-standard-errors-epidemiologists - 2025-04-23