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Epigenetic differences arise during the lifetime of monozygotic twins

Monozygous twins share a common genotype. However, most monozygotic twin pairs are not identical; several types of phenotypic discordance may be observed, such as differences in susceptibilities to disease and a wide range of anthropomorphic features. There are several possible explanations for these observations, but one is the existence of epigenetic differences. To address this issue, we examin

Constructing librarians’ information literacy expertise in the domain of nursing

This article investigates negotiations of librarians’ expertise in relation to information literacy at the micro-level, specifically in the domain of nursing education. A qualitative empirical framework is employed. The study draws on 18 semi-structured interviews, 16 with Swedish nursing students, one with a librarian and one with a nursing professor. Three themes on librarians’ expertise emerge

Chironomidae (Diptera, Nematocera) fauna in three small streams of Skania, Sweden

Two unpolluted streams and one chemically and thermally polluted stream in Skania, Sweden, were investigated in summer 1995 for their temporary chironomid fauna and the occurrence of buccal deformities. The unpolluted streams 'Ovedsan' and 'Skaralidbacken' each contained, respectively, 13 and 16 taxa, with a dominance of Microtendipes pedellus group and Micropsectra spp., respectively. Most taxa w

Cellular uptake of C4b-binding protein is mediated by heparan sulfate proteoglycans and CD91/LDL receptor-related protein

CO-binding protein (C4BP) is a protein acting as a complement inhibitor and a carrier protein for anticoagulant protein S. Previously, we reported that the in vivo clearance of C4BP involves CD91, and that a CD91-interactive site overlaps the heparin-binding site within COP alpha-chains [26]. Here, we investigated the C4BP-CD91 interaction in more detail. Binding of C4BP to CD91 was unaffected by

Interdialytic weight gain and ultrafiltration rate in hemodialysis: Lessons about fluid adherence from a national registry of clinical practice

Excessive interdialytic weight gain (IWG) and ultrafiltration rates (UFR) above 10 mL/h/kg body weight imply higher morbidity and mortality. This study aimed to estimate the prevalence of high fluid consumers, describe UFR patterns, and describe patient characteristics associated with IWG and UFR. The Swedish Dialysis DataBase and The Swedish Renal Registry of Active Treatment of Uremia were used

Peptidergic and non-peptidergic innervation and vasomotor responses of human lenticulostriate and posterior cerebral arteries

The aim of the present study was to compare in man the innervation pattern and the functional responses to neuronal messengers in medium sized lenticulostriate and branches of the posterior cerebral arteries (PCA). The majority of the nerve fibers found were sympathetic and displayed specific immunoreactivity for tyrosine hydroxylase (TH) and neuropeptide Y (NPY). Only few nerve fibers displayed v

Detection of Bronchial Function of NHBD Lung Following One-h Warm Ischemia by Organ Bath Model

This study investigated the feasibility and effects of organ bath to be used for detection of bronchial function of non-heart-beating donor (NHBD) lung after 1-h warm ischemia. Sixteen Swedish pigs were divided into two groups randomly: heart-beating donor (HBD) group and NHBD with 1-h warm ischemia (NHBD-1 h) group. The bronchial rings whose lengths and inner diameters were both 1.5 mm were obtai

Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets

We recently finemapped a type 1 diabetes (T1D)-linked region on chromosome 21, indicating that one or more T1D-linked genes exist in this region with 33 annotated genes. In the current study, we have taken a novel approach using transcriptional profiling in predicting and prioritizing the most likely candidate genes influencing beta-cell function in this region. Two array-based approaches were use

Stand transpiration and sapflow density in relation to weather, soil moisture and stand characteristics

Sapflow density was measured in six stands in a boreal forest in central Sweden, to assess its dependence on soil moisture and stand characteristics. The stands were mixed and pure Scots pine and Norway spruce stands, which were between 34 and 105 years old. Sapflow was measured in 12 trees per stand using the Granier method during two contrasting growing seasons; one warm and dry and one wet and

Wake visualization of a heaving and pitching foil in a soap film

Many fish depend primarily on their tail beat for propulsion. Such a tail is commonly modeled as a two-dimensional flapping foil. Here we demonstrate a novel experimental setup of such a foil that heaves and pitches in a soap film. The vortical flow field generated by the foil correlates with thickness variations in the soap film, which appear as interference fringes when the film is illuminated w

Solar activity during the last 1000 yr inferred from radionuclide records

Identification of the causes of past climate change requires detailed knowledge of one of the most important natural factors-solar forcing. Prior to the period of direct solar observations, radionuclide abundances in natural archives provide the best-known proxies for changes in solar activity. Here we present two independent reconstructions of changes in solar activity during the last 1000 yr, wh

Dinophysis blooms in the deep euphotic zone of the Baltic Sea: do they grow in the dark?

In situ growth rates of the toxin-producing dinoflagellate Dinophysis norvegica collected in the central Baltic Sea were estimated during the summers of 1998 and 1999. Flow cytometric measurements of the DNA cell cycle of D. norvegica yielded specific growth rates (μ) ranging between 0.1 and 0.4 per day, with the highest growth rates in stratified populations situated at 15–20 m depth. Carbon upta