One of the most widely used tools for assessing and communicating scienti c uncertainty is Grading of Recommendations Assessment, Development, and Evaluation (GRADE), a system for rating the quality of evidence and grading strength of recommendations in healthcare. More than 100 organisations around the world—WHO included1— are using GRADE or have endorsed it.In GRADE, a quantitative assessment of

The impedance matching concept is employed in this paper to select the optimum gain of a VSC-HVDC damping controller. The damping controller of the DC link is based on control of active power in proportion to the difference in local frequency at the VSC-HVDC converter stations. To explain impedance matching, the small-disturbance electro-mechanical dynamics of a power system is transformed to an e

Morphological and optical properties were studied and also evolutionary changes of the eye lenses of some species of terrestrial gastropod pulmonate molluscs were traced. It was demonstrated that all examined properties of the lenses are typical for terrestrial pulmonates. In the course of evolution due to habitat shift by mollusks the lenses were changed only slightly.

Peak matched multiple windows are found as the Karhunen-Loeve basis functions of a predefined peaked spectrum. With a penalty function, an optimization procedure can be constrained with resulting control of sidelobes. Weighting factors, included in the averaging of the periodograms, can be designed to fulfill certain constraints. Desirable properties are low variance and small bias. This paper pre

Many analyses and debates developed in the last decades around trade unions’ revitalisation, pointing to different national traditions in the varieties of capitalism. Gender equality adds a new perspective to these debates, showing that women can be a crucial test for, and an instrument of, trade union revitalisation. In the current situation in Italy, what are the main challenges facing working w

Background: Gender, possibly due to the influence of gonadal hormones, is presumed to play a role in the pathogenesis of multiple sclerosis (MS), but no studies have evaluated whether male infertility is associated with MS. Objective: To study the association between male factor infertility and prevalent as well as incident MS. Method: Our cohort was established by linkage of the Danish National i

The aim of this study is to explore the ethics of the Nag Hammadi text, The Tripartite Tractate. This text, the fifth tractate in Nag Hammadi Codex I, has received comparatively little attention, although it is the most detailed Valentinian treaty still extant. By investigating the ethics of The Tripartite Tractate, this study not only illuminates a previously unstudied aspect of this very interes

Type 1 diabetes, formerly known as juvenile diabetes or insulin-dependent diabetes, results from the specific autoimmune destruction of the pancreatic islet beta cells. The subsequent lack of insulin leads to increased blood and urine glucose. The classical symptoms are polyuria (frequent urination), polydipsia (increased thirst), polyphagia (increased hunger), and weight loss. The disease may be

Scattering of electromagnetic waves by discrete, randomly distributed objects inside a (finite or semi-infinite) slab is addressed. In general, the non-intersecting scattering objects can be of arbitrary form, material and shape with number density n0 (number of scatterers per volume). The main aim of this paper is to calculate the coherent reflection and transmission characteristics for this conf

We have calculated relative binding affinities for eight tetrafluorophenyl-triazole-thiogalactoside inhibitors of galectin-3 with the alchemical free-energy perturbation approach. We obtain a mean absolute deviation from experimental estimates of only 2–3 kJ/mol and a correlation coefficient (R2) of 0.5–0.8 for seven relative affinities spanning a range of up to 11 kJ/mol. We also studied the effe

Cross Laminated Timber (CLT) at in-plane beam loading conditions present a very complex stress state and many failure modes need to be considered in design. The work presented here aims at finding improvements of a specific analytical model for stress analysis and strength verification that has been suggested in literature and which is also suggested as a basis for design equations for the next ve

The latest discovery of microfossils from the lower Cambrian (Fortunian Stage) Zhangjiagou Lagerstätte in South China are presented. This lagerstätte is rich in exceptionally preserved microfossils, including embryos of Olivooides multisulcatus, Olivooides mirabilis, and Pseudooides prima; hatched stages of O. multisulcatus, O. mirabilis, Hexaconularia sichuanensis, and Quadrapyrgites quadratacris

A model for global supply of sand, gravel and cut stone for construction based on a system dynamics model was developed for inclusion in the WORLD6 model. The Sand-Gravel-Stone model simulates production and market supply, demand and price for natural sand and gravel, sand and gravel from crushed rock and cut stone. The model uses market mechanisms where the demand is depending on population size,

En hållbar omställning av transportsystemet kan komma att kräva olika typer av bränslen, tekniker och infrastrukturförändringar, och som ett möjligt alternativ finns biodrivmedel. En potentiell resurs för biodrivmedelsproduktion i Sverige är svartlut, en ligninrik biprodukt från pappers- och massaindustrin, som kan förgasas och omvandlas till metanol. Mängden svartlut som finns tillgänglig begräns

Radar signature measurements of targets with or without camouflage in different backgrounds using airborne SAR are complex and expensive. Measurements at many orientations as well as illumination angles have to be performed for each target for completeness. A more efficient solution is to use ground based ISAR measurements of the desired targets and then blend these images into measured SAR scenes

Objective: Retrograde open mesenteric stenting (ROMS) through laparotomy was introduced as an alternative to surgical bypass in patients with acute mesenteric ischemia (AMI). The purpose of this study was to evaluate the indications and outcomes of ROMS for treatment of AMI and chronic mesenteric ischemia. Methods: We reviewed the clinical data and outcomes of all consecutive patients treated by R