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Antibiotic prescribing in relation to diagnoses and consultation rates in Belgium, the Netherlands and Sweden : use of European quality indicators

Objective: To assess the quality of antibiotic prescribing in primary care in Belgium, the Netherlands and Sweden using European disease-specific antibiotic prescribing quality indicators (APQI) and taking into account the threshold to consult and national guidelines. Design: A retrospective observational database study. Setting: Routine primary health care registration networks in Belgium, the Ne

How does a physical activity programme in elementary school affect fracture risk? : A prospective controlled intervention study in Malmo, Sweden

Objectives: Recent evidence from the 7-year followup of the Pediatric Osteoporosis Prevention (POP) study indicates an inverse correlation between years of participation in a physical activity (PA) intervention and fracture risk in children. However, we could not see a statistically significant reduction in fracture risk, which urged for an extension of the intervention. Setting: The study was con

Pluralism in Search of Sustainability: Ethics, Knowledge and Methdology in Sustainability Science

Sustainability Science is an emerging, transdisciplinary academic field that aims to help build a sustainable global society by drawing on and integrating research from the humanities and the social, natural, medical and engineering sciences. Academic knowledge is combined with that from relevant actors from outside academia, such as policy-makers, businesses, social organizations and citizens. Th

On Heat Transfer Issues for Wind Energy Systems

Control of heat transfer is important in wind power systems. In cold climate, the problems of icing and de-icing of the turbine blades need to be handled by efficient heat transfer technologies. Heat-generating components like electric generator, gear box, and frequency converters usually need cooling under operation by various cooling solutions such as air cooling, liquid cooling, and evaporative

Treatment of contaminated greywater using pelletised mine water sludge

Precipitated sludge (ochre) obtained from a mine water treatment plant was considered as an adsorbent substance for pollutants, since ochre is relatively free from problematic levels of toxic elements, which could impair on the quality of water to be treated. Artificially created ochre pellets from mixing Portland cement with raw ochre sludge were utilised to remediate either high (HC) or low (LC)

Model of nearshore random wave transformation : validation against laboratory and field data

This paper presents a two-dimensional numerical model of nearshore random wave transformation with a focus on model calibration and verification with both laboratory and field data. The model is based on the energy balance equation including diffraction and dissipation terms (Mase, 2001). The energy dissipation is determined based on the formulation by Dally et al. (1985), with new expressions for

Improving enzymatic activities and thermostability of a tri-functional enzyme with SOD, catalase and cell-permeable activities

Synergistic action of major antioxidant enzymes, e.g., superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) is known to be more effective than the action of any single enzyme. Recently, we have engineered a tri-functional enzyme, 6His-MnSOD-TAT/CAT-MnSOD (M-TAT/CM), with SOD, CAT and cell-permeable activities. The protein actively internalized into the cells and showed super

Terrestrial support of lake food webs: Synthesis reveals controls over cross-ecosystem resource use

Widespread evidence that organic matter exported from terrestrial into aquatic ecosystems supports recipient food webs remains controversial. A pressing question is not only whether high terrestrial support is possible but also what the general conditions are under which it arises. We assemble the largest data set, to date, of the isotopic composition (d2H, d13C, and d15N) of lake zooplankton and

Real-time in situ analysis of biocorona formation and evolution on silica nanoparticles in defined and complex biological environments

Biomolecules such as proteins immediately adsorb on the surface of nanoparticles upon their exposure to a biological environment. The formed adlayer is commonly referred to as biomolecule corona (biocorona) and defines the biological activity and toxicity of the nanoparticle. Therefore, it is essential to understand in detail the biocorona formation process, and how it is governed by parameters li

Tight global linear convergence rate bounds for Douglas–Rachford splitting

Recently, several authors have shown local and global convergence rate results for Douglas–Rachford splitting under strong monotonicity, Lipschitz continuity, and cocoercivity assumptions. Most of these focus on the convex optimization setting. In the more general monotone inclusion setting, Lions and Mercier showed a linear convergence rate bound under the assumption that one of the two operators

Realizing the energy potential of forest biomass in Sweden – How much is environmentally sustainable?

Harvesting of wood for bioenergy purpose will probably increase in importance in the future, in order to replace fossil fuel. However, the environmental impact of increased harvesting might be considerable, e.g. on soil and water chemistry, biodiversity and long-term productivity, and in this study we investigate thresholds for sustainable harvesting volumes. The study is based on scientific revie

Conversion of lignin model compounds by Pseudomonas putida KT2440 and isolates from compost

Starting from mature vegetable compost, four bacterial strains were selected using a lignin-rich medium. 16S ribosomal RNA identification of the isolates showed high score similarity with Pseudomonas spp. for three out of four isolates. Further characterization of growth on mixtures of six selected lignin model compounds (vanillin, vanillate, 4-hydroxybenzoate, p-coumarate, benzoate, and ferulate)

Self-reported exposure to severe events on the labour ward among Swedish midwives and obstetricians : A cross-sectional retrospective study

Background The process of delivery entails potentially traumatic events in which the mother or child becomes injured or dies. Midwives and obstetricians are sometimes responsible for these events and can be negatively affected by them as well as by the resulting investigation or complaints procedure (clinical negligence). Objective To assess the self-reported exposure rate of severe events among m

Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery

Following stroke, complete cellular death in the ischemic brain area may ensue, with remaining brain areas undergoing tissue remodelling to various degrees. Experience-dependent brain plasticity exerted through an enriched environment (EE) promotes remodelling after central nervous system injury, such as stroke. Post-stroke tissue reorganization is modulated by growth inhibitory molecules differen

Radial tunnel diodes based on InP/InGaAs core-shell nanowires

We report on the fabrication and characterization of radial tunnel diodes based on InP(n+)/InGaAs(p+) core-shell nanowires, where the effect of Zn-dopant precursor flow on the electrical properties of the devices is evaluated. Selective and local etching of the InGaAs shell is employed to access the nanowire core in the contact process. Devices with an n+-p doping profile show normal diode rectifi

Cross-border mergers & acquisitions with financially constrained owners

Mergers give acquirers control over the assets of the merged entity and give sellers control over financial assets. We propose a cross-border merger model with home biased financially constrained owners in which the subsequent investments of the buyer and the seller can be determined. We show that policies blocking foreign acquisitions to protect the domestic industry can be counterproductive. For

Global stroke statistics

Background: Up to date data on incidence, mortality, and case-fatality for stroke are important for setting the agenda for prevention and healthcare. Aims and/or hypothesis: We aim to update the most current incidence and mortality data on stroke available by country, and to expand the scope to case-fatality and explore how registry data might be complementary. Methods: Data were compiled using tw