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BEER-The Beamline for European Materials Engineering Research at the ESS

The Beamline for European Materials Engineering Research (BEER) will be built at the European Spallation Source (ESS). The diffractometer utilizes the high brilliance of the long-pulse neutron source and offers high instrument flexibility. It includes a novel chopper technique that extracts several short pulses out of the long pulse, leading to substantial intensity gain of up to an order of magni

Neutron guide shielding for the BIFROST spectrometer at ESS

We report on the study of fast-neutron background for the BIFROST spectrometer at ESS. We investigate the effect of background radiation induced by the interaction of fast neutrons from the source with the material of the neutron guide and devise a reasonable fast, thermal/cold neutron shielding solution for the current guide geometry using McStas and MCNPX. We investigate the effectiveness of the

Evaluation of data mining tools for telecommunication monitoring data using design of experiment

Telecommunication monitoring data requires the automation of data analysis workflows. A data mining tool provides data workflow management systems to process and perform analysis tasks. This paper presents an evaluation of two example data mining tools following the principles of design of experiment (DOE) to run forecasting and clustering workflows for telecom monitoring data. We conduct both qua

Systematic assessment of pharmaceutical prescriptions in association with cancer risk : a method to conduct a population-wide medication-wide longitudinal study

It is a public health priority to identify the adverse and non-adverse associations between pharmaceutical medications and cancer. We search for and evaluate associations between all prescribed medications and longitudinal cancer risk in participants of the Swedish Cancer Register (N = 9,014,975). We associated 552 different medications with incident cancer risk (any, breast, colon, and prostate)

Associations between neurodevelopmental disorders and factors related to school, health, and social interaction in schoolchildren : Results from a Swedish population-based survey

Background Children and adolescents with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are more likely to be surrounded by different risk factors. In order to work preventively with decreasing ADHD and ASD symptoms, there is a need of more knowledge concerning risk factors. Objective This study aimed to investigate school, health, lifestyle and social interactio

Peripheral sensory neurons expressing melanopsin respond to light

The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to mediate light-induced pain but recent evidence raises the possibility of an alternative light responsive pathwa

Drive-characteristic design for dual-input Doherty power amplifiers

Doherty power amplifiers (PAs) can achieve high efficiency with modulated signals since they exhibit an efficiency-peak in backoff that can, in theory, reach full-scale efficiency. Unfortunately, the backoff efficiency of real Doherty PAs is lowered by unavoidable losses. The purpose of this work is to study the potential of re-gaining some of this efficiency loss through nonlinear drive-curve des

Multi-Grid boron-10 detector for time-of-flight spectrometers in neutron scattering science

The Multi-Grid (MG) detector has been introduced at ILL and developed by a collaboration between ILL, ESS and Linkoping University. This detector design addresses the severely decreased availability of He3, in particular for neutron scattering instruments with large-area detectors, such as time-of-flight neutron spectrometers at ESS and other facilities. The MG detector is based on thin converter

Attending physicians believe that hospitalized patients are treated at the appropriate level of care : A qualitative study

The purpose of this paper is to investigate the appropriateness of hospitalized patients’ level of care as assessed by their treating physicians. The study was conducted as a qualitative study, based on a questionnaire. The study suggests that physicians generally believe that patients who occupy in-hospital beds are cared for at the appropriate level of care. It is worth to note that a relatively

Establishment of an international database for genetic variants in esophageal cancer

The establishment of a database has been suggested in order to collect, organize, and distribute genetic information about esophageal cancer. The World Organization for Specialized Studies on Diseases of the Esophagus and the Human Variome Project will be in charge of a central database of information about esophageal cancer–related variations from publications, databases, and laboratories; in add

Filling the Gap – Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient : A European Consensus View

Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group. Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general p