Objective: The aim of the study was to determine survival outcome in patients with serous cancer in the ovary, fallopian tube, peritoneum and of undesignated origin. Methods: Nation-wide population-based study of women. ≥. 18. years with histologically verified non-uterine serous cancer, included in the Swedish Quality Registry for primary cancer of the ovary, fallopian tube and peritoneum diagnos

Psoriasis (PSO) and psoriatic arthritis (PsA) are two related chronic inflammatory diseases. A proportion of people with PSO also develop PsA. PSO and PsA seem to have multiple impacts; from the health and well-being of the individual; to the need for healthcare resources for disease management; to the loss of productivity. Compared with other chronic diseases, such as heart disease and diabetes,

The relay autotuner provides a simple way offinding PID controllers of sufficient performance. By usingan asymmetric relay function the excitation of the process isimproved. This gives better models, and hence a better tuning,without increasing the time consumption or complexity of theexperiment. Some processes demand more accurate modelingand tuning to obtain controllers of sufficient performanceThe relay autotuner provides a simple way offinding PID controllers of sufficient performance. By usingan asymmetric relay function the excitation of the process isimproved. This gives better models, and hence a better tuning,without increasing the time consumption or complexity of theexperiment. Some processes demand more accurate modelingand tuning to obtain controllers of sufficient performance

Background: There is a lack of understanding of the factors that influence independent mobility and participation in meaningful activities. The purpose of this study was to analyse physical factors influencing independent use of manual and power wheelchairs in a total population of children with cerebral palsy (CP). Methods: A cross-sectional study based on the most recent examination of all child

Det är inte alla teknologer som antas till en civilingenjörsutbildning som verkligen tar examen. Vid LTH har, till exempel, bara var tionde teknolog tagit examen inom den nominella tiden 4.5 år. Inte förrän efter 6 år har hälften tagit examen och efter 15 år är det fortfarande en tredjedel av dem som en gång antogs som saknar examen. Inspirationen till denna studie var behovet att försöka hitta nåDet är inte alla teknologer som antas till en civilingenjörsutbildning som verkligen tar examen. Vid LTH har, till exempel, bara var tionde teknolog tagit examen inom den nominella tiden 4.5 år. Inte förrän efter 6 år har hälften tagit examen och efter 15 år är det fortfarande en tredjedel av dem som en gång antogs som saknar examen. Inspirationen till denna studie var behovet att försöka hitta nå

Interferon regulatory factor-8 (IRF8) has been proposed to be essential for development of monocytes, plasmacytoid dendritic cells (pDCs) and type 1 conventional dendritic cells (cDC1s) and remains highly expressed in differentiated DCs. Transcription factors that are required to maintain the identity of terminally differentiated cells are designated “terminal selectors.” Using BM chimeras, condit

NADPH-DIAPHORASE (NADPHd) is known to be identical to nitric oxide (NO) synthase in the mammalian nervous system, and is therefore used as a marker of NO-producing neurones. Using the histochemical reaction for NADPHd, we searched for such neurones in a selection of invertebrates. Special emphasis was given to molluscs. No selective neuronal staining was found in representatives of coelenterates,

Platelets contribute to inflammation however, the role of platelet activation during the pathophysiological response to invasive bacterial infection and sepsis is not clear. Herein, we have investigated platelet activation in a mouse model of invasive Streptococcus pyogenes infection at 5,12, and 18 hours post infection and correlated this to parameters of infection. The platelet population in ex-

Background: WNT5A (-/-) mammary tissue has been shown to exhibit increased ductal elongation, suggesting elevated mammary cell migration. Increased epithelial cell migration/invasion has often but not always been linked to the epithelial-mesenchymal transition (EMT). In the current study, we investigated the loss of WNT5A in HB2 human mammary epithelial cells and hypothesized that this loss increa

Background: The St Gallen surrogate definition of the intrinsic subtypes of breast cancer consist of five subgroups based on estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor type 2 (HER2), and Ki-67. PgR and Ki-67 are used for discriminating between the ‘Luminal A-like’ and ‘Luminal B-like (HER2-negative)’ subtypes. Histological grade (G) has prognostic v

Objective: To test whether plasma tau is altered in Alzheimer disease (AD) and whether it is related to changes in cognition, CSF biomarkers of AD pathology (including β-amyloid [Aβ] and tau), brain atrophy, and brain metabolism. Methods: This was a study of plasma tau in prospectively followed patients with AD (n 179), patients with mild cognitive impairment (n 195), and cognitive healthy control

BACKGROUND: Malignant pediatric brain tumors constitute a heterogeneic group of central nervous system tumors, and general markers of diagnosis and prognosis are not available. Recently, a panel of CD markers (CD15, CD24, CD29) was used to define increasing neural differentiation of embryonic stem cells. Although these CD markers have been associated with worse prognosis due to presence of tumor p

AIMS: To evaluate the usefulness of the signed value of monophasic action potential duration difference in analysing the cause of dispersion of ventricular repolarization.METHODS AND RESULTS: Monophasic action potentials were simultaneously recorded from the right ventricular apex and outflow tract during programmed stimulation in 36 patients with ventricular arrhythmias. The time difference betwe

Background: Patients treated for Pediatric Brain Tumors (PBTs) often experience a decline/stagnation in their cognitive functioning.Anumber of potential risk factors for cognitive decline have been identified including gender (female), young age-at-diagnosis, higher baseline IQ, hydrocephalus at diagnosis, treatment with Whole Brain Radiation Therapy (WBRT), and larger radiation field and/or dose.

We show in this Letter a novel approach for high-contrast imaging through scattering media by combining structured illumination and Fourier filtering (SIF). To assess the image contrast enhancement at different image spatial frequencies, the modulation transfer function is calculated for four detection schemes: (1) no filtering, (2) Fourier filtering, (3) structured illumination, and (4) SIF filte