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Accelerometer derived physical activity and subclinical coronary and carotid atherosclerosis : cross-sectional analyses in 22 703 middle-aged men and women in the SCAPIS study

OBJECTIVES: The aim included investigation of the associations between sedentary (SED), low-intensity physical activity (LIPA), moderate-to-vigorous intensity PA (MVPA) and the prevalence of subclinical atherosclerosis in both coronaries and carotids and the estimated difference in prevalence by theoretical reallocation of time in different PA behaviours.DESIGN: Cross-sectional.SETTING: Multisite

Evaluation of recombinant human IGF‑1/IGFBP‑3 on intraventricular hemorrhage prevention and survival in the preterm rabbit pup model

Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates processesof vascular maturation. The pathogenesis of intraventricular hemorrhage (IVH) relates to the fragilityof the immature capillaries in the germinal matrix, and its inability to resist fluctuations in cerebralblood flow. In this work, using different experimental setups, we aimed to (i) establish an

Psychosocial study environment characteristics associated with exposure to sexual harassment at a large public university in southern Sweden : a cross-sectional study

BACKGROUND: Universities can be understood as work-like environments for students, with similar risks and expectations regarding psychosocial environment. Limited research has examined this study environment from a Demand-Control-Support perspective with regard to sexual harassment. Understanding this environment is key to designing protective measures. This study aimed to examine the association

Dilemmas on emicizumab in children with haemophilia A : A survey of strategies from PedNet centres

Introduction: Haemophilia A care has changed with the introduction of emicizumab. Experience on the youngest children is still scarce and clinical practice varies between haemophilia treatment centres. Aim: We aimed to assess the current clinical practice on emicizumab prophylaxis within PedNet, a collaborative research platform for paediatricians treating children with haemophilia. Methods: An el

Evacuation training as a part of fire strategies for timber buildings

With biobased buildings making the transition into mainstream construction, the safety of their occupants needs to be adequately ensured, since the introduction of combustible building materials is bearing fundamental ramifications for fire safety strategies of such buildings. The present work introduces a research project on safe evacuation of timber buildings. More specifically, it targets to in

Learning-Based Dimensionality Reduction for Computing Compact and Effective Local Feature Descriptors

A distinctive representation of image patches in form of features is a key component of many computer vision and robotics tasks, such as image matching, image retrieval, and visual localization. State-of-the-art descriptors, from hand-crafted descriptors such as SIFT to learned ones such as HardNet, are usually high-dimensional; 128 dimensions or even more. The higher the dimensionality, the large

Experimental study on effects of ammonia enrichment on the thermoacoustic instability of lean premixed swirling methane flames

Ammonia (NH3) has recently emerged as a promising carbon-free energy carrier. Further development and application of NH3 as fuel in the gas turbine industry can significantly reduce the emissions of carbon dioxide (CO2) and contribute to the achievement of a carbon–neutral society. This study experimentally examined the thermoacoustic instability characteristics of a laboratory-scaled lean premixe

Neuromas cause severe residual problems at long-term despite surgery

Pain, and disabilities after neuroma surgery, using patient reported outcome measurements (PROMs), were evaluated by QuickDASH and a specific Hand Questionnaire (HQ-8). The 69 responding individuals (response rate 61%; 59% women; 41% men; median follow up 51 months) reported high QuickDASH score, pain on load, cold sensitivity, ability to perform daily activities and sleeping difficulties. Individ

Seasonal variation and importance of catchment area composition for transport of bioavailable carbon to the Baltic Sea

Transport of terrestrial carbon through riverine systems to coastal water has a negative impact on oxygen concentration in coastal areas. However, information on seasonal variation and the impact of catchment composition on the bioavailability of allochthonous carbon is lacking. In this project we address this knowledge gap by investigating the reactivity of dissolved organic carbon (DOC) at river

White paper on psychodermatology in Europe : A position paper from the EADV Psychodermatology Task Force and the European Society for Dermatology and Psychiatry (ESDaP)

Psychodermatology is a subspecialty of dermatology that is of increasing interest to dermatologists and patients. The case for the provision of at least regional psychodermatology services across Europe is robust. Psychodermatology services have been shown to have better, quicker and more cost-efficient clinical outcomes for patients with psychodermatological conditions. Despite this, psychodermat

Long-term outcomes of an internet-delivered cognitive enhancement intervention targeting residual cognitive deficits after major depressive disorder : a 2-year follow-up of an open trial

Background: Cognitive deficits are common and disabling residual symptoms following major depressive disorder (MDD) and are related to increased risk of relapse. Residual cognitive deficits should thus be considered an important target for treatment. However, few have reported long-term outcomes of interventions targeting residual cognitive deficits. Objective: This study aimed to (1) investigate

Bioenergy crops, biodiversity and ecosystem services in temperate agricultural landscapes—A review of synergies and trade-offs

The Paris agreement on climate change requires rapid reductions in greenhouse gas emissions. One important mitigation strategy, at least in the intermediate future, is the substitution of fossil fuels with bioenergy. However, using agriculture- and forest-derived biomass for energy has sparked controversy regarding both the climate mitigation potential and conflicts with biodiversity conservation.

Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons

Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content. The MHC genes have expanded in passerine birds, resulting in numerous MHC paralogs, with relatively high sequence similarity, making the assembly of the MHC reg

Gender Smart Mobility : Concepts, Methods, and Practices

This book presents gender and diversity in smart transport as a cutting-edge issue in urban contexts around the globe. It addresses new challenges and possibilities related to the smart transport sector. It demonstrates how gender and diversity are entangled in concepts and various forms of current smart mobility practices in policy, planning, and innovation. Gender Smart Mobility is presented as

Visual acuity in patients with non-functioning pituitary adenoma : Prognostic factors and long-term outcome after surgery

Background: Visual acuity (VA) and visual field defects (VF) are evaluated in the preoperative management of non-functioning pituitary adenoma (NFPA). The former is less studied than the latter. Research question: To analyze preoperative factors, including adenoma volumetry, associated with reduced VA and postoperative improvement of VA over five years after surgery. Methods: Eighty-seven patients

Hypertension management in primary health care : a survey in eight regions of Sweden

Purpose: To explore hypertension management in primary healthcare (PHC). Design: Structured interviews of randomly selected PHC centres (PHCCs) from December 2019 to January 2021. Setting: Seventy-six PHCCs in eight regions of Sweden. Main outcome measures: Staffing and organization of hypertension care. Methods of measuring blood pressure (BP), laboratory tests, registration of co-morbidities and

Realizing the AF4-UV-SAXS on-line coupling on protein and antibodies using high flux synchrotron radiation at the CoSAXS beamline, MAX IV

In this paper, we demonstrate the coupling of synchrotron small angle X-ray scattering (SAXS) to asymmetrical flow-field flow fractionation (AF4) for protein characterization. To the best of our knowledge, this is the first time AF4 is successfully coupled to a synchrotron for on-line measurements on proteins. This coupling has potentially high impact, as it opens the possibility to characterize i