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Chronic inflammation in the etiology of disease across the life span

Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and lifestyle factors can promote systemic chronic inflammation (SCI) that can, in turn, lead to several diseases that collectively represent the leading causes of disability and mortality worldwide, such as cardiovascular d

The evolutionary ecology of plant reproductive diversity and floral signals : Mating system and floral scent in Arabis alpina

Flowering plants display an extraordinary floral- and reproductive diversity. Variation in the size, shape, colour and scent of flowers, and in systems and strategies of mating, is ubiquitous in comparisons of different species, but also exists among different conspecific populations. Diversity in these characters is central to the evolution of flowering plants and the formation of new species. In

Successful aging : Insights from proteome analyses of healthy centenarians

Healthy aging depends on a complex gene-environment network that is ultimately reflected in the expression of different proteins. We aimed to perform a comparative analysis of the plasma proteome of healthy centenarians (n=9, 5 women, age range 100-103 years) with a notably preserved ambulatory capacity (as a paradigm of 'successful' aging), and control individuals who died from a major age-relate

Who chooses to enroll in a new national gambling self-exclusion system? A general population survey in Sweden

Background: Self-exclusion from gambling is a common method for prevention and harm reduction in hazardous gambling. However, few national self-exclusion programs, involving a large number of gambling operators and activities in a country, have been assessed scientifically. This study aimed to examine characteristics of individuals who chose to enroll in a recently introduced (January, 2019) natio

Gambling During the COVID-19 Crisis - A Cause for Concern

: The COVID-19 pandemic has the potential to worsen mental health problems in the general population, including increasing engagement in addictive behaviors. Here, we describe observations suggesting that the current crisis and its sequelae may worsen problem gambling. The current pandemic may impact financial and psychological well-being due to social isolation during spatial distancing, and thes

Changes in gambling behavior during the COVID-19 pandemic—A web survey study in Sweden

The COVID-19 pandemic has dramatically changed everyday life, and policy makers have raised concerns about possible changes in gambling patterns during the pandemic. This study aimed to examine whether self-reported gambling has increased during the pandemic, and to examine potential correlates of such a change. This general population survey study in Sweden collected self-report data from 2016 we

Protocol for a multi-site study of the effects of overdose prevention education with naloxone distribution program in Skåne County, Sweden

Background: Continuously high rates of overdose deaths in Sweden led to the decision by the Skåne County to initiate the first regional take-home naloxone program in Sweden. The project aims to study the effect of overdose prevention education and naloxone distribution on overdose mortality in Skåne County. Secondary outcome measures include non-fatal overdoses and overdose-related harm in the gen

The general population’s view on where to seek treatment for gambling disorder – a general population survey

Background: More remains to be understood about attitudes towards treatment for gambling disorder and where to seek treatment. Given the low degree of treatment seeking behaviour in this condition, it may be of interest to study people’s perception about where to seek help in case of problem gambling. From a study originally aiming to address health correlates of problem gambling, the present sub-

Self-Limiting Polymer Exposure for Vertical Processing of Semiconductor Nanowire-Based Flexible Electronics

In this work, we demonstrate a vertical processing method to fabricate nanowire (NW)-based devices. This method combines the strong light absorption ability caused by the NW geometry and exposure to dose-dependent clearance properties of a photo-sensitive polymer. By embedding NW arrays in a polymer, the NW light absorption leads to self-limited exposure and selective removal of the polymer. This

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Anthropogenic pressure and global change are favouring the increase of infectious diseases not only in humans but also in wildlife. The negative effects of pathogens can be devastating, affecting natural populations and even causing the extinction of species. Therefore, it is fundamental to understand the mechanisms and strategies that these agents develop during their life cycle, as well as the i

Reliability and construct validity of five life domains in the adolescent drug abuse diagnosis instrument in a sample of Swedish adolescent girls in special residential care

Aim: This cross-sectional study investigates the psychometric properties of the Swedish edition of the Adolescent Drug Abuse Diagnosis (ADAD), and specifically examines the internal consistency and construct validity of five life domains reported by female adolescents in special residential care in Sweden (N = 780; Mage = 16 years old). Methods: Principal component analysis and entropy-based analy

Gaia and Hubble Unveil the Kinematics of Stellar Populations in the Type II Globular Clusters ? Centauri and M22

The origin of multiple stellar populations in globular clusters (GCs) is one of the greatest mysteries of modern stellar astrophysics. N-body simulations suggest that the present-day dynamics of GC stars can constrain the events that occurred at high redshift and led to the formation of multiple populations. Here, we combine multiband photometry from the Hubble Space Telescope (HST) and ground-bas

Testing and Improving the IntCal20 Calibration Curve with Independent Records

Connecting calendar ages to radiocarbon (C) ages, i.e. constructing a calibration curve, requires C samples that represent, or are closely connected to, atmospheric C values and that can also be independently dated. In addition to these data, there is information that can serve as independent tests of the calibration curve. For example, information from ice core radionuclide data cannot be directl

Decay studies of the long-lived states in Tl 186

Decay spectroscopy of the long-lived states in Tl186 has been performed at the ISOLDE Decay Station at ISOLDE, CERN. The α decay from the low-spin (2-) state in Tl186 was observed for the first time and a half-life of 3.4-0.4+0.5 s was determined. Based on the α-decay energy, the relative positions of the long-lived states were fixed, with the (2-) state as the ground state, the 7(+) state at 77(5

Chemical absorption of carbon dioxide in non-aqueous systems using the amine 2-amino-2-methyl-1-propanol in dimethyl sulfoxide and N-methyl-2-pyrrolidone

Non-aqueous amine systems have been suggested as energy-efficient alternatives to conventional aqueous amine systems in post-combustion carbon capture, as low regeneration temperatures can be achieved. The solubility of CO2 and heat of absorption in non-aqueous systems were studied using the sterically hindered amine 2-amino-2-methyl-1-propnaol (AMP) in the organic solvent dimethyl sulfoxide (DMSO

On the topology of vortex structures and heat transfer of a gas turbine blade internal tip with different arrangement of delta-winglet vortex generators

This paper aims to provide a novel enhanced heat transfer method for the internal tip surface of a U bend channel of relevance for a gas turbine rotor blade. The DWVGs (delta-winglet vortex generators) pair is arranged at multiple locations on the tip surface. Two types of vortex generators are studied, including common-flow-up and common-flow-down configurations. The inlet channel Reynolds number

Analysis of spatial co-occurrence between cancer and cardiovascular disease mortality and its spatial variation among the Swedish elderly (2010–2015)

CVD and cancer are the two leading causes of death worldwide. Improvement in cancer early detection and treatment has resulted in an increased number of cancer survivors. However, many of the survivors tend to develop CVD often leading to their demise. Conversely, people with pre-existing CVD conditions, especially the elderly, have increased chances of developing cancer and dying from the same. T