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Bispecifika antikroppar bygger broar mellan immunförsvaret och cancerceller – potentiell ny cancerbehandlingsform Prekliniska försök av en ny bispecifik antikropp aktiverar en av immunförsvarets nyckelspelare mot cancerceller från matstrups- och magsäckscancer. Kroppen är utrustad med sitt eget superförsvar, immunsystemet, som varje dag röjer undan olika hot i vår kropp. Det är ett välutvecklaImmune check inhibitors (ICI) are promising tools in the fight against cancer, increasing the effect of Cytotoxic T Lymphocytes (CTL). However, their efficacy can be limited in tumors with poor CTL infiltration or priming, and strategies enhancing this is of great interest. Dual targeting of CD40 on APCs, and a tumor associated antigen (TAA), is one possible approach, promoting tumor-specific CTL

This thesis explores the architectural potential of compressed wool as a natural material capable of forming complex structures. From the beginning, the project combined two main directions: first, the exploration of natural, growth-based patterns such as differential growth and hyperbolic surfaces, and second, the investigation of material behavior through direct experimentation. These two paths

Mer data och tydligare svar: Avancerad ultraljudsteknik med magnetism för bättre cancerdiagnostik Rektalcancer är ett vanligt förekommande problem som ökar i samhället. För att minska lidande för patienter och eventuell överbehandling finns det vinning i att snabbt och effektivt kunna kartlägga spridningen. Detta arbete har undersökt metoder för att snabbare skapa tydliga bilder av spridningen tiRectal cancer is a common type of cancer, and the escalating prevalence is correlated to the western lifestyle. Most patients will undergo surgery, where the extent of the surgery correlates with the tumor stage. Determining the spread to neighboring lymph nodes is challenging, as certain evaluation requires biopsy of the resected tissue. Therefore, NanoEcho is currently developing a diagnostic to

The recent developments in stochastic and quantum thermodynamics has laid the foundation for developing highly efficient devices that utilizes quantum effects. One such device is a quantum dot heat engine, that consists of one or more quantum dots tunnel coupled to two leads. By tuning the energy levels of the quantum dots appropriately one can obtain a flow of electrons through the quantum dot sy

metamorphic /ˌmet.əˈmɔː.fɪk/ n. (of rock) changed into a new form and structure by very great heat and pressure. - Cambridge University Press. n.d. Metamorphic. In Cambridge Dictionary. The Ba Son complex was originally a shipyard built for constructing warships during the Nguyen Dynasty in the 1800s. Over time, it has undergone countless changes while witnessing significant historical events. O

Oat grains contain high levels of phytic acid, an anti-nutritional compound that reduces nutrient bioavailability, along with notably low phytase activity, the enzymatic mechanism responsible for phytic acid degradation. Malting of oats prior to human consumption is a recognized method to reduce phytic acid content by inducing phytase expression, thereby enhancing the nutritional value of oats. Th

En av de viktigaste molekylerna för levande organismer är vatten, och det är ingen slump att det är just vatten som efterlyses när astronomer letar efter planeter som kan innehålla liv. En sådan viktig molekyl måste kunna transporteras in och ut ur våra celler på ett pålitligt sätt. Detta görs av proteiner som fungerar som kanaler för vatten i våra cellmembran: så kallade aquaporiner. Det finns måAquaporin 2 (AQP2) is a membrane channel protein that is in humans most importantly found at the end of the renal collecting duct. A lack of AQP2 in the apical membrane can lead to diabetes insipidus (DI), characterized by dehydration and dilute urine, making protein-protein interactions between AQP2 and other proteins an important field of study. In this study, the interaction between an AQP2 con

This paper examines the economic consequences of financial crises and the determinants of recovery duration through a structural-institutionalist perspective. Drawing on cross-country data from 160 countries (1950–2019) and using updated classifications of crisis episodes, it explores two central questions: how do different types of crises affect GDP per capita? and what factors explain variation

Battery Electric Vehicles (BEVs) are increasingly adopted as sustainable alternatives to shift fossil fuel reliance. However, because of battery dependence, their heating systems face significant efficiency losses due to frost formation on heat exchangers in cold climates. This study investigates a capacitance-based sensing approach to detect ice buildup on automotive heat exchangers, aiming to op

This thesis explores how gamification affects respondent engagement and data quality in online surveys. A between-subjects experiment with 203 participants compared a gamified survey featuring progress bars, rewards, feedback, and a storyline with a non-gamified version. The study was guided by the Technology Acceptance Model 2, Self-Determination Theory, and Flow Theory. Results showed that gamif

Kan spelardetektion på en plan förbättras genom att öka antalet kameror som används för detektionen? Med utvecklingen av artificiell intelligens (AI) och maskininlärning har möjligheterna inom en rad områden ökat markant, exempelvis sportteknologi. Där används AI för att automatiskt detektera spelare på en plan med hjälp av kamerabilder. I det här arbetet undersöks hur en AI-modell kan förbättra dAccurate detection of player positions is essential for sports analysis. Traditional single-camera methods generally suffer from occlusion and diminishing resolution far away. This work proposes using multi-camera Bird's Eye View (BEV) detection to overcome these issues. Synthetically generated data was used to train and test the detection model, which uses images from six cameras placed aroun

This project explores how a beginner friendly music production device can lower the threshold for engaging with sound creation and rhythm making. Many existing tools rely on prior knowledge or technical skill, which discourages new users from experimenting in creative ways. This project instead focuses on quick feedback, clear interaction and a tactile experience that invites curiosity and play. T

I Lund pågår byggandet av det nordsydliga cykelstråket. På de centralare delarna av detta stråk varierar utformningen av cykelinfrastrukturen och på några av delar med smala vägprofiler har det valts att utforma cykelfält. Denna rapport ämnar att redogöra hur ofta cykelfälten blockeras och undersöka om den nuvarande lösningen ger en god säkerhet och framkomlighet för cyklister. För detta har videIn Lund, construction is underway on the north-south cycling route. In the more central parts of this route, the design of the cycling infrastructure varies, and in some sections with narrow road profiles, bike lanes have been chosen as the design solution. This report aims to describe how often the bike lanes are obstructed and to examine whether the current solution provides good safety and acc

This thesis addresses the challenge of strategic inventory positioning faced by a focal firm that lacks visibility and control over its supply chain and therefore depends on integration with external suppliers to enable inventory positioning. Furthermore, due to the resources required for integration, the thesis rests on the premise that a focal firm has to prioritize which suppliers to integrate

This thesis investigates the climate impact of a newly constructed residential complex in Oceanhamnen, Helsingborg, through an extended life cycle assessment (LCA) covering both building and non-building elements such as road infrastructure, inner courtyards, external installations, that area often overlooked in conventional assessments. The aim is to develop a replicable method to quantify the gl

This essay examines the Hungarian Prime Minister Viktor Orbán's rhetoric on Russia's war in Ukraine, how it constructs Hungary's national identity and its implication for Hungary's foreign policy. The analysis is based on a Critical Discourse Analysis, which serves to critically analyse Orbán's statements in interviews, speeches and social media, among others. By analyzing Orbá

Detta examensarbete handlar om att beskriva hur kreativa processer såsom flow kan se ut i en musikers vardag. Vidare berör arbetet hur musiker kan berika sin kreativitet och konstnärlighet genom att kombinera musikaliska aktiviteter med teoretiska resonemang och problemlösning. Arbetet lyfter fram att grundläggande faktorer som kost, sömn, återhämtning och trygghet är avgörande för ett hållbart muThis thesis explores how creative processes take shape in the everyday lives of musicians and how they can be enriched through a combination of practical musicianship and theoretical reflection. Through semi-structured interviews with musicians, along with personal reflections, the thesis highlights how creativity and artistic expression can be strengthened by conscious problem-solving and critica

Traditionally rooted in a linear economy model, the European food industry is now rapidly shifting towards circular supply chain systems. Compared to the previous model, this approach offers significant environmental and socio-economic benefits, including greater resource efficiency, waste reduction, and increased market competitiveness. Despite a clear theoretical framework based on the principle

In recent years, discussions regarding problematic school absenteeism have increased in research and media. The Swedish National Agency for Education (Skolverket) observed an increase in both valid and invalid absences among students attending compulsory school in 2023, compared to previous years. Using Michael Lipsky's theory of street-level bureaucrats, which encompasses alienation, discreti