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Membrane-active peptides (MAPs) are able to induce pores in cell membranes via molecular mechanisms, which are still subject to ongoing research. In this work, we present molecular dynamics simulations that suggest a precursor membrane defect plays an important role in the pore-inducing activity of the prototypical antimicrobial peptide melittin. The simulations reveal that the hydrophobic N-termi

Nutrients constrain the soil carbon cycle in tropical forests, but we lack knowledge on how these constraints vary within the soil microbial community. Here, we used in situ fertilization in a montane tropical forest and in two lowland tropical forests on contrasting soil types to test the principal hypothesis that there are different nutrient constraints to different groups of microorganisms duri

Horseflies (Tabanidae) are polarotactic, being attracted to linearly polarized light when searching for water or host animals. Although it is well known that horseflies prefer sunlit dark and strongly polarizing hosts, the reason for this preference is unknown. According to our hypothesis, horseflies use their polarization sensitivity to look for targets with higher degrees of polarization in thei

Svenska Dagbladet 19/11 2017, understreckare med anledning av att antologin "Tre sekler av svenska pekoral" är under utgivning.

Having multiple control tasks concurrently running on a single computing platform increases the processor utilization but degrades the control performance due to delay and jitter. In scheduling and control codesign, the objective is to optimize the combined performance of all the controllers, subject to a schedulability constraint. The codesign procedure consists of selecting task parameters, e.g.

Oxylipins, or fatty aldehydes, are a class of molecules produced from membrane lipids as a result of oxidative stress or enzyme-mediated peroxidation. Here we report the effects of two biologically important fatty aldehydes, trans,trans-2,4-decanedienal (DD) and cis-11-hexadecenal (HD), on the phase behavior of the lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) in water. We compare the

Funerary poems on animals form a subgenre of the standard epitaph written to commemorate a deceased person. The poet who created the conditions necessary for the establishment of this kind of poetry in Sweden was the queen dowager Hedvig Eleonora’s court poet Erik Lindschöld (1634–1690); his poems mourning the death of the queen’s bitches were presumably composed in the 1670s. These poems constitu

Seed orchards function as the primary source of high-quality seeds for reforestation in many European countries, but their seed yields can be severely reduced due to seed- and cone-feeding insects. We evaluated various parameters of pheromone-based mating disruption for control of the moths Cydia strobilella and Dioryctria abietella, which are major pests in European Picea abies seed orchards. We

Hypoxia (i.e., low oxygen levels) is a known feature of aggressive tumors. Cells, including tumor cells, respond to conditions of insufficient oxygen by activating a transcriptional program mainly driven by hypoxia-inducible factors (HIF)-1 and HIF-2. Both HIF-1α and HIF-2α expression levels have been shown to correlate to patient outcome in various tumor forms and in neuroblastoma, a solid childh

The BLAS2T (bilingual aphasia in stroke-study team) initiative has been a multi-center attempt to investigate longitudinal changes in language function in a cohort of stroke subjects. This report discusses linguistic performance in four cases from the BLAS2T database who demonstrated coprolalia as an irresistible urge to say obscene words. Coprolalia was found to partly resolve in a 30-day follow-

Background: Relapse from drug abuse (DA) is common, but has rarely been studied in general population samples using a wide range of objective predictors. Method: Using nationwide registries, we ascertained 44 523 subjects first registered for DA between the ages of 15 and 40 in 1998 to 2004 and followed for 8 years. We predicted relapse in subjects defined as a second DA registration. We also pred

Forskningen i denna avhandling handlar i hög grad om att försöka härma kemin i jordens atmosfär. Den sista mätningen till denna avhandling gjordes för bara några veckor sedan, under ett fruktmellanmål tillsammans med mina barn. Jag bestämde mig för att testa ett otroligt påstående som säger att om jorden krymptes ihop till ett äpple är atmosfären lika tunn som äpplets skal. D.v.s.:tjocklek(äppleskApart from gases, the air we breath consist of tiny, so called, aerosol particles. A cubic metre of air in a relatively clean environment can consist of several billion aerosol particles. The impact of these particles on human health and on climate is significant. According to WHO, particles affect more humans than any other pollutant, and is closely related to mortality and morbidity. Further, it

The Coulomb explosion of the hydrogen molecule, after absorption of a 76eV photon, has been studied by momentum imaging the two electrons and the two protons. Absolute fully differential cross sections of high statistical quality are obtained. A subset of the overall data, namely, equal electron-energy sharing, is used to investigate the effects of molecular orientation on the photoelectron angula

2-color Xe photo-double-ionization is investigated after absorption of one XUV high order harmonic photon and few infrared Ti:Sapphire laser photons. Double ionization is found to happen predominantly step wise via intermediate excited Xe+ states.

Two-colour experiments combining synchrotron radiation and light pulses from a synchronized linear dye laser have been performed to investigate even-parity Xe* 5p5 (2P1/2) np′ and nf′ resonances of atomic xenon. These autoionization states have been reached through a double-resonant excitation scheme including the short-lived intermediate states Xe* 5p5(2P3/2) 5d and 6d. Our theoretical results re