The work described in this thesis represents a biophysical approach, mainly using nuclear magnetic resonance (NMR) spectroscopy, to investigate the impact of magnesium ions on the EF-hand calcium-binding proteins calmodulin and calbindin D9k, as well as the dynamics of these proteins at low calcium levels. The x-ray structure of magnesium-saturated calbindin D9k shows a magnesium ion in only one o

Kort framställning av en forskningsbaserad bild av den historiske Jesus i lärobok på akademisk basnivå

Popular Abstract in Swedish Ändamålet med studien var att identifiera prognostiska och etiologiska riskfaktorer för melanom och dess relation till histopatologi. Studie 1-3 innefattade 711 patienter från 1965-1989. Vi fann en mediantjocklek som varierade mellan 1,1 och 1,4 mm, utan något statistiskt förändring genom åren och en ökning av andelen tunna tumörer (The purpose was to study the prognostic and aetiologic risk factors for melanoma in correlation to histopathology. Paper 1-3: Thin tumours (

Glimtvis har vårt släkte kunnat fånga kärnan: ”… vad livet är och var hitom tanken och bortom samhället: i det tankfulla betraktandet av en bergart som är vackrare än allt vi lyckats producera eller i förnimmelsen av en liljas doft som ger oss mer än alla visa böcker eller i den tålamodsmättade, lugna och ömsesidigt förlåtande blinkning man ibland i plötsligt samförstånd kan växla med en katt” (Cl

To improve gas turbine performance, the operating temperature has been increased continuously. However, the heat transferred to the turbine blade is substantially increased as the turbine inlet temperature is increased. Cooling methods are therefore needed for the turbine blades to ensure a long durability and safe operation. The blade tip region is exposed to the hot gas flow and is difficult to

Popular Abstract in Swedish Zeoliter är en grupp av kisel-aluminium-föreningar, med karaktäristiska kanalsystem inuti strukturen, som har fått stor användning inom många områden inom teknik och vetenskap. Zeoliternas viktigaste användningsområden är som torkmedel, som molekylsiktar, som jonbytare och som katalysatorer. Användningen av naturligt förekommande zeoliter är relativt liten jämfört med aA highly dealuminated form of zeolite FAU, ultra-stable zeolite Y (USY), was used as an adsorbent matrix in the purification of proteins. Undesired proteins were removed from a crude preparation by adsorption on USY, increasing the purity of an unadsorbed protein (horse radish peroxidase), or the protein of interest was adsorbed on the zeolite and subsequently eluted through changes in the solutio

The aim was to study and prospectively follow symptoms and sensitisation of laboratory animal workers with laboratory animal allergy (LAA) and workers at risk for development of LAA in terms of latency time, incidence, prevalence and possible health selection. Furthermore, the impact of animal positive skin prick tests (SPT) on lung function and individual risk factors for development of LAA was s

History plays an important role in the philosophy of human rights, more so than in philosophical discussions on related concepts, such as justice. History tends to be used in order to make it credible that there is a tradition of rights as a moral idea, or an ethical ideal, that transcends national boundaries. In the example that I investigate in this chapter, this moral idea is tightly spun aroun

The main objective of this paper is to develop a proven model which allows the study of the non-stationary effects in district heating systems, which are associated with time lag, between heat generation and the final consumption of the heat. A finite element model was developed which incorporates one-dimensional fluid elements together with thermal elements sets. This enables a description of the

In this thesis, two questions are answered: What is burnout?, and What causes burnout? Essentialist conceptions of burnout are criticized and burnout is regarded as a syndrome in the sense of a practice concept, not possible to delineate exactly. Practice concepts are compared to social constructions. From the syndrome idea, the Maslach Burnout Inventory (MBI), is chosen as an operationalization o