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Structure and magnetism of ultrathin epitaxial Fe on Ag(100)

We have made in-situ investigations of ultrathin films of Fe grown on a Ag(100) single crystal. This system is known to exhibit a reorientation of the magnetization, dependent on both Fe thickness and temperature. X-ray absorption fine structure has been recorded for samples prepared in-situ, both in the near edge and in the extended x-ray absorption fine structure (EXAFS) region. Using x-ray magn

Cytoskeletal Regulation During Embryonic Development in Drosophila melanogaster

The development of multicellular organisms is associated with extensive rearrangements of cells and tissues. The driving force for these rearrangements is generated by the cell's actin cytoskeleton. During many morphogenetic processes dynamic rearrangement of the actin cytoskeleton is regulated by small GTPases of the Rho-family. These GTPases are highly conserved throughout the animal kingdom and

How do Swedish paediatric clinics diagnose coeliac disease? Results of a nationwide questionnaire study

Background and aim: Diagnosis of coeliac disease is based on the demonstration of enteropathy in a small bowel biopsy. Correct diagnosis is of utmost importance, since the need for dietary management is life long, and inadequate treatment may lead to potentially serious complications. The Swedish Working Group for Paediatric Coeliac Disease has published guidelines for the diagnosis of childhood c

Transforming growth factor-beta induces selective increase of proteoglycan production and changes in the copolymeric structure of dermatan sulphate in human skin fibroblasts

Human embryonic skin fibroblasts were pretreated with transforming growth factor-beta (TGF-beta) for 6 h and then labeled with [35S]sulphate and [3H]leucine for 24 h. Radiolabeled proteoglycans from the culture medium and the cell layer were isolated and separated by isopycnic density-gradient centrifugation, followed by gel, ion-exchange and hydrophobic-interaction chromatography. The major prote

Decision Making in Fire Risk Management

Various normative decision theories are discussed in the context of fire risk management. A method suitable for practical decision making in respect to fire safety investments is presented and exemplified. The method involves the use of second-order probabilities to represent uncertainty regarding probability values. A discussion on the use of Bayes theorem in combination with decision analysis is

SF-36 scores in degenerative lumbar spine disorders: Analysis of prospective data from 451 patients.

Background When using Health-Related Quality of Life (HRQoL) in assessing outcomes of treatment, normative data for different diagnoses are needed to allow cross-comparisons of existing and future studies. We determined the SF-36 scores in patients with surgical lumbar spine problems. Methods This is a prospective observational study of consecutive surgical patients in one institution. In additi

How representative are clinical study patients with asthma or COPD for a larger "real life" population of patients with obstructive lung disease?

Evidence-based medicine is a corner stone in treatment decision making and large randomised, clinical trials are usually designed in order-to provide highly significant results. This study was conducted in order to find out to what extend a "real life" patient population with obstructive lung disease could fit into criteria commonly used in clinical research trials. As a secondary aim of the study

Observation of vestibular asymmetry in a majority of patients over 50 years with fall-related wrist fractures

Previously [The abstract has been shortened somewhat, and the headings removed, in order to conform to journal style], we have observed vestibular asymmetry in about one-third of healthy senior citizens and in about two-thirds of subjects with previous hip fractures and no other significant ailments. Wrist fractures are considered a harbinger of hip fractures. If vestibular asymmetry is correlated

Structural and Functional Studies of Gas6

The vitamin K-dependent and ubiquitously expressed 82 kDa glycoprotein product of the growth-arrest-specific-gene 6, Gas6, shows 44% sequence identity to the anticoagulant protein, protein S. Both proteins share further the same domain organization. A short loop region, 4 epidermal growth factor-like modules and an SHBG-like region follow the N-terminal Gla-domain, which confers membrane-binding c

Prostate specific antigen based biennial screening is sufficient to detect almost all prostate cancers while still curable

PURPOSE: We evaluated whether biennial screening with prostate specific antigen (PSA) only is sufficient to detect prostate cancer while still curable. MATERIALS AND METHODS: In Goteborg, Sweden 9,972 men 50 to 65 years old were randomized to PSA screening. During 1995 and 1996 these men were invited for a first PSA screening and invited during 1997 and 1998 for a second screening. The screening p

Morphogenesis in the nematode-trapping fungus Arthrobotrys oligospora - an extensive plasticity of infection structures

st nematode-trapping fungi are dependent on specific hyphal structures on or in which nematodes can be trapped mechanically or by adhesion. These structures are a prerequisite for the ability of the fungus to invade a host and are thus crucial for survival as well as virulence. The diversity of trapping structures is large and highly dependent on the environment of the fungus. Within one single sp

Shaping variables in service level agreements at application level

In a web service environment, such as Parlay X, contracts are agreed between the involved participants to guarantee a reasonable measure of Quality of Service (QoS). A common policy adopted is for contracts to involve only one parameter which places a limit on the number of incoming operation calls. This constraint is expressed as the maximum number of operation calls per second that a source is a

Abnormal uterine Doppler is related to vasculopathy in pregestational diabetes mellitus

Background - The aim of the study was to evaluate the relation between maternal placental Doppler velocimetry, levels of the maternal glucose, and clinical signs of vasculopathy in pregnancy complicated by pregestational diabetes mellitus. Methods and Results - A retrospective study of 155 pregestational diabetic women between the 22nd and 40th weeks of pregnancy, categorized in White classificati

Cardiotonic bipyridine amrinone slows myosin-induced actin filament sliding at saturating [MgATP]

Previously reported effects of amrinone on skeletal muscle function suggest that the drug reduces the rate constant of myosin cross-bridge dissociation. We have used the in vitro motility assay to further elucidate the mechanism underlying this effect and to aid these studies a new, improved,. lament tracking software was developed in the Matlab(TM) environment. The experiments were carried out at