Parkinson’s disease (PD) is the most common neurodegenerative disorder, characterized by slow progressive loss of dopamine (DA) neurons in the substantia nigra, located in the ventral midbrain. Although the relatively focal degeneration in PD makes it a good candidate for cell-based therapies, obtaining cell source on large scale clinical application remains a challenge. It has now been shown that

Enhancing Therapeutic Genes to cure Neurodegenerative diseases Alzheimer’s and Parkinson’s are the leading cause of neurodegenerative disease around the world. Research so far has only progressed towards reducing the symptoms linked with these diseases with no cure having been developed. Alzheimer’s and Parkinson’s share similar pathology in the way that they develop and form protein clumps which

Syftet med denna studie är att undersöka hur professionella musiker reflekterar över sin identitet, yrkesidentitet och passion i sken av coronapandemin som präglat 2020 och 2021. Vi vill se hur de tänker kring dessa teman då allt kulturliv helt stängdes ner hösten 2020 och ingen verksamhet kunde bedrivas. Vi har genomfört 10 kvalitativa intervjuer med individer som helt eller delvis försörjer sig

The flesh-eating bacterium and inflammation run amok Streptococcus pyogenes is a bacterium that can infect humans and cause a wide range of symptoms, from the common strep throat to life-threatening infections. In rare cases, when this bacterium pushes its way down into our deeper skin layers, like in necrotizing skin and soft-tissue infection (NSTI), the destruction of the local tissue sometimes

Methicillin-resistant Staphylococcus aureus (MRSA) colonises up to 30% of the population and is responsible for diseases ranging from mild skin infections to endocarditis, some of which result in death. This is due to the resistance of MRSA to several commonly used as well as last line antibiotics, complicating treatment further. This study examines clinical MRSA isolates with inactivating mutatio

Bakgrund: I takt med att allt fler barn med lägre födelsevikt och kortare graviditetslängd kan räddas kommer barn och deras familjer i kontakt med avancerad sjukvård under en längre tid i början av barnets liv. NIDCAP är en modell som utvecklades med utgångspunkt hos det för tidigt födda barnets behov genom kunskap om barnets beteende och familjens särskilda vårdbehov. Från NIDCAP har FINE utveckl

Green prescribing, the referral of patients to nature-based activities, has potential to bring co- benefits for psychological and physiological public health and for environmental health. Literature considers a major limitation to its effective implementation as a holistic, transectoral practice to be lack of a common language and tendency of actors involved to work within their respective paradig

This paper investigates the impact of financial development as a bi-dimensional concept on inequality in a regional comparison of Asian as well as Latin American countries. The policy has previously been explicitly proposed for middle-income economies to boost growth and overall prosperity. While allowing for nonlinearities, this paper exploits both static, fixed effects as well as dynamic GMM est

Följande studie strävar efter att sammanställa uppfattningar och insikter hos erfarna pianolärare på gymnasium i frågor kring gehör och notläsning. Samtliga informanter undervisar främst i gehörsmusik som jazz och rock/pop. Studien använder sig av kvalitativa intervjuer Målet är att ta reda på lärares syn på nyttan deras gymnasieelever har i ett starkt gehör och i notläsningskunskaper. Studien undThe study aims at compiling the views of experienced piano teachers at gymnasium in matters of playing music, hearing based and/or by reading music. All participants in the study teach mainly in hearing-based genres such as jazz and rock/pop. The study is using qualitative interviews. The aim is to find out the teachers views about which use their students may have of hearing based compared to not

Estimating depth from an image is an ill-fitted problem, since we project a three-dimensional space to a two-dimensional image. However, human can estimate a plausible depth from only a single eye and often are we relaying on this for quick estimation of moving objects. Although machine learning has shown to be powerful in computer vision tasks, the process of constructing deep learning models is

Electric cars are by many considered a sustainable solution to the ever-growing demand for road vehicles and fuel. The transportation sector is responsible for almost a third of the total greenhouse gas emissions globally and approximately 80% of these emissions can be attributed to road vehicles. Thus, there is an urgent need for a shift away from fossil fuels in the sector. While the consumer in

Abstract Title: Which accounting principle will the Swedish insurance industry choose? A qualitative study of factors that affect unlisted insurance companies' choice of accounting principle. Seminar date: 2 June 2021. Course: FEKH69 Degree Project Undergraduate level, Business Administration, 15 University Credit Points. Authors: Emil Adméus, Petronella Sandberg, William Rönnlund. Advi

Titel: Regulated Booked Values or Macroeconomics? Seminariedatum: 02/06/2021 Kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, Företagsekonomi, 15 högskolepoäng Författare: Nikolaos Karabelas, Tim Vindehall, Simon Wallin Handledare: Karin Jonnergård Nyckelord: Värderelevans, IFRS, OMXS30, Bokförda värden, Ohlson-modellen Frågeställning: Vilka faktorer har haft en effekt på marknadsvärdetTitle: Regulated Booked Values or Macroeconomics? Seminar date: 02/06/2021 Course: FEKH69, Degree Project Undergraduate Level, Business Administration, 15 University Credits Points (UPC) Authors: Nikolaos Karabelas, Tim Vindehall, Simon Wallin Supervisor: Karin Jonnergård Key words: Value Relevance, IFRS, OMXS30, Booked Values, Ohlson model Research question: Which factors had an effect on the ma

In this thesis, dynamically controlled machine learning algorithms running on state of the art Arm microNPUs, with an attached Cortex-M CPU, were investigated. The machine learning framework used was Tensorflow and different subsets of it, such as Tensorflow Lite micro. Compiling the network to run on the microNPU was done with the use of an open-source compiler called, Vela. In order to investiga

Since the beginning of wireless communication, one of the central problems has been resource management and maximization of network throughput. Solving these recurring issues is an important topic in the field of wireless communication to increase application options and the user experience. The existing methods for solving the issue of inter cell interference by maximizing the network capacity ar

HBTQIA+ personer i Sverige är relativt jämställda med heterosexuella cis-personer i jämförelse med andra länder men det finns tidigare forskning som visar på att det finns informella processer som förhindrar den jämställdheten. Syftet med studien är därför att belysa dessa processer och se hur de påverkar homosexuella personer i Sverige för att synliggöra eventuella problem. Studien avgränsar sig

Laser induced shockwaves have previously been shown to prompt structural changes in germanium. Similar experiments have now been performed in InSb, with powder diffraction patterns displaying a peak at 2.3Å indicating the formation of an unknown structure. In this work, large scale molecular dynamics simulations of shockwave propagation in germanium and InSb are presented. The results are in excel

Aviation is known to be safe, partly due to highly specialized pilots who undergo extensive training to fulfill and maintain their function at the sharp end. More demands are placed on the pilots as complexity continues to grow in aviation. This is due to more technology, more rules of compliance, more diversity in operations, and less time to do it all in the aggressive competitive world of avia

The aim of this paper is to examine how the covid-19 pandemic and the restrictions around have effected domestic violence against women in Sweden. The year 2020 has been affected hard by the coronavirus spreading throughout the world. Alot of nations applied a lockdown strategy to fight the spread of the virus. Sweden choosed to handle things differently and let the government give out recommendat

The momentum effect is a persistent and stable phenomenon, achieving very high abnormal returns, which could not yet be explained by conventional pricing models. However, this very high returns are punctuated by extreme strategy crashes leading to high losses, for which investors need decades to recover from. This makes momentum less attractive for risk-averse investors and motivates an appropriat