Protein G, the immunoglobin G-binding surface protein of group C and G streptococci, also binds serum albumin. The albumin-binding site on protein G is distinct from the immunoglobulin G-binding site. By mild acid hydrolysis of the papain-liberated protein G fragment (35 kDa), a 28-kDa fragment was produced which retained full immunoglobulin G-binding activity (determined by Scatchard plotting) bu

Proteins in solution move subject to a complex superposition of global translational and rotational diffusion as well as internal relaxations covering a wide range of time scales. With the advent of new high-flux neutron spectrometers in combination with enhanced analysis frameworks it has become possible to separate these different contributions. We discuss new approaches to the analysis by prese

Background: Macrophage migration inhibitory factor is a proinflammatory cytokine that has been associated with various psychiatric disorders. MicroRNA-451a can directly target macrophage migration inhibitory factor and downregulate its expression in cells. However, the role of macrophage migration inhibitory factor and microRNA-451a in psychiatric patients treated with psychotherapeutic interventi

In this study, the heat and mass transport characteristics of anode-supported solid oxide fuel cells (SOFCs) are numerically investigated by using a two-dimensional model. The mathematical model is validated by comparing the numerical results with experimental data found in the open literature. The species and temperature distributions of SOFCs at different cell voltages are presented and compared

Sepsis is associated with dysfunctional coagulation. Recent data suggest that platelets play a role in sepsis by promoting neutrophil accumulation. Herein, we show that cecal ligation and puncture (CLP) triggered systemic inflammation, which is characterized by formation of IL-6 and CXC chemokines as well as neutrophil accumulation in the lung. Platelet depletion decreased neutrophil accumulation,

Den sjungande trappuppgången är en TV-serie i sex avsnitt på SVT med start 6 februari 2012. Med inspiration från engelsk förlaga handlar serien om experimentet, att samla en större grupp människor med olika ålder och bakgrund, boende i samma förortsstadsdel utan större kontakt med sina grannar, och tillsammans bilda en sångkör med målet att uppträda vid offentliga konserter.

Traditionally, atherosclerosis has been evaluated macroscopically from the presence of fatty streaks (FS), fibrous plaques (FBP), and complicated lesions (CL). In this preliminary study, employing aortas from autopsied middle-aged or older persons we investigated the fatty raised lesion (FRL) to elucidate its significance and histological features. The FRL is determined macroscopically from its di

We investigate the propagation of electromagnetic waves in a cylindrical waveguide with an arbitrary cross section filled with a nonlinear material. The electromagnetic field is expanded in the usual eigenmodes of the waveguide, and the coupling between the modes is quantified. We derive the wave equations governing each mode with special emphasis on the situation with a dominant TE mode. The resu

Objective. To study the impact of the utilization of antibiotics in children at the population level on the frequency of penicillin-nonsusceptible pneumococci (PNSP). Design. Children ages 0 to 6 years with a nasopharyngeal culture of PNSP were registered on place of residency in the 20 municipalities of the former Malmohus County (since 1998 a part of Skane County). Where possible the total numbe

A search for singly produced vector-like quarks Q, where Q can be either a T quark with charge +2/3 or a Y quark with charge −4/3, is performed in proton–proton collision data at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 36.1 fb−1, recorded with the ATLAS detector at the LHC in 2015 and 2016. The analysis targets Q → Wb decays where the W boson decays leptonica

In this paper, we present a robust multipath-based localization and mapping framework that exploits the phases of specular multipath components (MPCs) using a massive multiple-input multipleoutput (MIMO) array at the base station. Utilizing the phase information related to the propagation distances of the MPCs enables the possibility of localization with extraordinary accuracy even with limited ba

The project How to think about a place not yet concerns the mechanisms and attitudes adopted by the professional designer in an urban design process – i.e. how intuitive and affective response in a design process delimit the range of plausible designs. The affordances of the environment are suited to the particular acting space of an individual and communicate the possibilities and capacities for

Institutional reworking, state-market-civil society synergy and participatory resettlement have created a spectacle for inclusive urban development with much celebrated academic focus on urban’s poor’s rights, entitlements and citizenship as approached through phenomenal ‘deepening of democracy’, ‘civic governmentality’ or ‘graduated urban citizenship’. At South Asia Across the Nordic Region 2019

The “wooded-meadows system” is a multifunctional use of vegetation resources widespread in Europesince the Neolithic, and well documented in the Ligurian Apennines (NW Italy) between the MiddleAges and the first half of the 19th century. The management of wooded-meadows included: collectionof fallen and dead branches in spring, later used for fuel; mowing and grazing in summer; collection ofsecond