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Pleural mesothelioma in Sweden: an analysis of the incidence according to the use of asbestos
OBJECTIVE: To investigate if the preventive measures taken to reduce the occupational exposure to asbestos have resulted in a decreased incidence of pleural mesothelioma in Sweden. METHODS: The incidence of pleural mesothelioma between 1958 and 1995 for birth cohorts born between 1885 and 1964 was investigated. The cases of pleural mesothelioma were identified through the Swedish Cancer Register.
From probabilistics to determinism: an essay on risk assessment and decisionmaking in sociotechnical systems
Probabilistic analysis is the usual starting point for sociotechnical risk assessments aimed at deciding whether or not a particular risk is acceptable. However, the available probabilistic evidence is usually insufficient as a basis for such decisions, and so the assessment has to be supplemented by a judgemental process of a more deterministic nature. This concluding phase in decisionmaking is e
Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor
1 We studied the effects of a thromboxane A2 receptor (TP receptor) antagonist, ICI-192,605 (0.5mgkg-', i.v.) and a selective thromboxane (Tx) synthetase inhibitor, OKY-046 (30mgkg-1, i.v.), on airway responses induced by leukotriene D4 (LTD4; 0.2 nmol) or prostaglandin F2a, (PGF2,; 20 nmol) instilled via the airways route to anaesthetized guinea-pigs. For a comparison, airway responses to a TxA2-
Introducing biological phosphorus removal in an alternating plant by means of control: a full scale study
In this paper, a control strategy for introducing enhanced biological phosphorus removal (EBPR) in an alternating plant designed for enhanced biological nitrogen removal (EBNR) is presented. Alternating aerobic and anaerobic conditions to promote EBPR are provided by controlling the phases of the operational cycle, instead of a separate anaerobic volume. By utilising the control schemes already bu
Simultaneous quantification of human glandular kallikrein 2 and prostate-specific antigen mRNAs in peripheral blood from prostate cancer patients
We present a multiplexed and internally calibrated quantitative reverse transcription-PCR (QRT-PCR) assay to detect human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) transcripts in blood samples from healthy subjects and prostate cancer (PC) patients. The assay detected 50 copies of hK2 and PSA mRNA, and 1 PSA- and 10 hK2-expressing LNCaP cells in the presence of 2.5 x 10(6) P
Effects of pH on Helicobacter pylori binding to human gastric mucins: Identification of binding to non-MUC5AC mucins
Helicobacter pylori causes gastritis, peptic ulcer disease and gastric cancer. The microbe is found in the gastric mucus layer where a pH gradient ranging from acidic in the lumen to neutral at the cell surface is maintained. The aim of the present study was to investigate the effects of pH on H. pylori binding to gastric mucins from healthy individuals. At pH 3, all strains bound to the most char
Common principles of sensory encoding in spinal reflex modules and cerebellar climbing fibres.
An important step towards understanding the function of olivo-cerebellar climbing fibres must be to clarify what they signal. We suggest that climbing fibres projecting to paravermal cerebellum mediate highly integrated sensorimotor information derived from activity in spinal withdrawal reflex modules acting on single forelimb muscles. To test this hypothesis, cutaneous nociceptive receptive field
Risk och historia : sex uppsatser om katastrofer och livets vanskligheter
Bilden av Fakiren
Genomgång av illustrationer till Axel Wallengrens "fakiriska" verk och hur dessa förhåller sig dels till själva texterna och dels till dessas upphovsman.
Transmission of BSA during Cross-flow Microfiltration: Influence of pH and Salt Concentration
In many downstream processes microfiltration (MF) is used as the first step to separate the micro-organisms from the product-containing broth. The transmission of proteins through these MF membranes is of great importance, especially when a protein is the desired product. Usually, the largest fraction of the proteins retained in the membrane during the separation of micro-organisms is retained in
Grundvattenvärme : kvarteret Tärnan i Landskrona
Rapporten redovisar fältförsök, uppföljning och termohydraulisk utvärdering av en experimentbyggnadsanläggning i kvarteret Tärnan i Landskrona. En låg energiförbrukning eftersträvas genom överglasad gata m.m.
Progression of retinopathy after improved metabolic control in type 2 diabetic patients. Relation to IGF-1 and hemostatic variables
OBJECTIVE: To determine the impact of improved glycemic control on the development and progression of retinopathy after the institution of insulin therapy in patients with type 2 diabetes and to assess the relation to IGF-1 and hemostatic variables. RESEARCH DESIGN AND METHODS: In a prospective observational study, 45 type 2 diabetic patients were examined at baseline and 1, 3, 6, 12, and 24 month
Bet v 1 homologues in strawberry identified as IgE-binding proteins and presumptive allergens
Background: No strawberry allergen has so far been identified and characterized. Methods: Serum samples were collected from patients with a suggestive case history of adverse reactions to strawberry and other fruits. Extracts from fresh and frozen strawberries were analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Western blotting and mass spectrometry. Patient blo
Vegetation history and lake-level changes from the Younger Dryas to the present in Eastern Pyrenees (France): pollen, plant macrofossils and lithostratigraphy from Lake Racou (2000 m a.s.l.)
A multi-proxy palaeoecological investigation including pollen, plant macrofossil, radiocarbon and sedimentological analyses, was performed on a small mountain lake in the Eastern Pyrenees. This has allowed the reconstruction of: ( 1) the vegetation history of the area based on five pollen diagrams and eight AMS(14)C dates and ( 2) the past lake-level changes, based on plant macrofossil, lithologic
Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation.
Reason and nature: Essays in the theory of rationality
Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005 - Data from the national prostate cancer register in Sweden
Objective. The incidence of prostate cancer is rising rapidly in Sweden and there is a need to better understand the pattern of diagnosis, tumor characteristics and treatment. Material and methods. Between 1996 and 2005, all new cases of adenocarcinoma of the prostate gland were intended to be registered in the National Prostate Cancer Register (NPCR). This register contains information on diagnos
Ska generna styra vad vi äter?
This article gives an overview of some ethical problems raised in connection to nutritional genomics, especially the use of knowledge from nutrigenomics as a basis for personalised nutrition after a genetic test.