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Lost and found: the enigmatic large-billed reed warbler Acrocephalus orinus rediscovered after 139 years

We present compelling evidence of the continued existence of the large-billed reed warbler Acrocephalus orinus, hitherto known only from the unique type specimen collected in NW India 139 years ago. Morphological and genetic analyses of an unusual Acrocephalus warbler mist-netted south-west of Bangkok, Thailand, on 27 March 2006, confirmed its identity as A. orinus, and revealed that it was hetero

The influence of RBE variations in a clinical proton treatment plan for a hypopharynx cancer

Currently, most clinical range-modulated proton beams are assumed to have a fixed overall relative biological effectiveness (RBE) of 1.1. However, it is well known that the RBE increases with depth in the spread-out Bragg peak (SOBP) and becomes about 10% higher than mid-SOBP RBE at 2 mm from the distal edge (Paganetti 2003 Technol. Cancer Res. Treat. 2 413-26) and can reach values of 1.3-1.4 in v

The influence of different kinds of pre-treatment on the performance of a polyamide nanofiltration membrane

Although pre-treatment of membranes is often used to ensure the reliability of experimental data, it also has the potential to improve many aspects of membrane performance. This study investigates the influence of chemical pre-treatment and wetting on membrane flux and retention. The results show that chemical pre-treatment, with either a phosphate buffer or alkaline cleaning agents, enhances the

Polyampholyte-induced repulsion between charged surfaces: Monte Carlo simulation studies

The force between two planar charged surfaces in the presence of polyampholytes (PAs) is investigated as a function of the surface separation. The model system contains PA molecules with zero net charge adsorbing onto the charged surfaces from a dilute surrounding solution without salt. We compare the results obtained on three levels of approximation: (i) polyampholytes moving in the mean field du

Biology

The hottest developments in the fields of cancer research, neuroscience, genomics and proteomics, anti-virals and more, with a pick of the key research papers in these areas.

Five-year follow-up of socket movements and loosening after revision with impacted morselized allograft bone and cement - A radiostereometric and radiographic analysis

In 1999, we reported on the 2-year results of a series of 21 first-time socket revisions using impacted morselized allograft bone. Seven still migrated between 1.5 and 2 years. Seventeen remained for the current 5-year follow-up. No socket had been rerevised. Five sockets showed signs of radiographic loosening. These 5 cases also exhibited radiographic signs of allograft resorption as well as high

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

X-linked agammaglobulinemia (XLA) is an immunodeficiency caused by mutations in the gene coding for Bruton's agammaglobulinemia tyrosine kinase (BTK). A database (BTKbase) of BTK mutations has been compiled and the recent update lists 368 entries from 318 unrelated families showing 228 unique molecular events. In addition to mutations the database lists also some polymorphisms and site-directed mu

Saving the woodpeckers: Social Capital, Governance, and Policy performance

This article investigates if higher levels of social capital, better governance structures, and a more ambitious conservation policy are positively linked to the ability of states to address biodiversity loss. Serving this purpose is a data set containing estimates of woodpecker diversity in 20 European countries. These data are argued to be a more valid indicator of biodiversity than most other a

HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine

The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day I and at 6-12 months intervals for up to 48 months, subjects underwent Papanicolaou and genital HPV testing. N

High tumor tissue concentration of plasminogen activator inhibitor 2 (PAI-2) is an independent marker for shorter progression-free survival in patients with early stage endometrial cancer.

Previous studies including various tumor types have shown different associations between tumor tissue levels of plasminogen activator inhibitor 2 (PAI-2) and patient survival. High tumor tissue concentrations of PAI-2 have been associated with good prognosis in patients with breast cancer, small cell lung cancer and ovarian cancer, but with poor histologic differentiation and poor prognosis in pat

Interactions between hairy rod anionic conjugated polyelectrolytes and nonionic alkyloxyethylene surfactants in aqueous solution: Observations from cloud point behaviour

The effect of three anionic, hairy-rod fluorene based conjugated polyelectrolytes on the cloud points of the alkyloxyethylene surfactants C10E3, C12E4, C12E5, and C12E6 has been studied in aqueous solution. Although the association behaviour of these rigid polymers with surfactants is different from that of more flexible polyelectrolytes, both types of polymers are seen to increase the cloud point

A geometric approach to Boolean matrix multiplication

For a Boolean matrix D, let r(D) be the minimum number of rectangles sufficient to cover exactly the rectilinear region formed by the 1-entries in D. Next, let m(D) be the minimum of the number of 0-entries and the number of 1-entries in D. Suppose that the rectilinear regions formed by the 1-entries in two n x n Boolean matrices A and B totally with q edges are given. We show that in time (O) ove

Can Phytophthora quercina have a negative impact on mature pedunculate oaks under field conditions?

Ten oak stands in southern Sweden were investigated to evaluate the impact of the root pathogen Phytophthora quercina on mature oaks under field conditions. Phytophthora quercina was present in five of the stands, while the other five stands were used as controls to verify the effect of the pathogen. In each stand, a healthy, a moderately declining and a severely declining tree were sampled. Fine-

Amniotic fluid S100B protein in mid-gestation and intrauterine fetal death

Fetal death in the mid-trimester of pregnancy is unexplained and no reliable markers are available to identify at-risk women. We aimed to assess use of a fetoprotein and S100B concentrations in amniotic fluid as markers. We did a case-control study in 758 healthy women undergoing amniocentesis at mid-gestation, of whom 12 had a spontaneous intrauterine fetal death before 28 weeks, and 746 matched

In the eye of both patient and spouse: memory is poor 1 to 2 years after coronary bypass and angioplasty.

BACKGROUND: The study aimed to investigate patient and spouse perception of cognitive functioning 1 to 2 years after coronary artery bypass grafting. METHODS: Seventy-six married patients who had undergone coronary artery bypass grafting were selected and sex- and age-matched with 75 concurrent married patients who had undergone percutaneous transluminal coronary angioplasty. Couples received a le

Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines

During complement activation the pro-inflammatory anaphylatoxins C3a and C5a are generated, which interact with the C3a receptor and C5a receptor (CD88), respectively. C5a and its degradation product C5a-des-Arg(74) also bind to the C5a receptor-like 2 (C5L2). C3a and C3a-des-Arg(77), also called acylation-stimulating protein, augment triglyceride synthesis and glucose uptake in adipocytes and ski