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Optimizing Monochromatic Focusing on ThALES

Neutron ray-tracing simulations have been done in order to study the interplay between an elliptically shaped guide end with two double focusing monochromators - pyrolytic graphite PG002 and bent Si111. The primary aim of these calculations has been the optimisation of the neutron optics of the new cold triple-axis spectrometer ThALES, the successor of the IN14 spectrometer at the Institut Laue-La

Sub-adult Ravens Synchronize their Play : A Case of Emotional Contagion?

Emotional contagion – the alignment of emotions between individuals through behavioral synchronization – is proposed as a key, basic component of human social cognition and empathy. In the field of cognitive zoology, contagious behaviors have also received attention. Several such behaviors have been documented in various species. Nevertheless, emotional and behavioral contagion differ. Emotional c

Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood-brain barrier.

Calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated anti-migraine efficacy. One remaining question is where do these blockers act? We hypothesized that the trigeminal ganglion could be one possible site. We examined the binding sites of a CGRP receptor antagonist (MK-3207) and related this to the expression of CGRP and its receptor in rhesus trigeminal ganglion. Pituitary

Biogeophysical feedbacks enhance the Arctic terrestrial carbon sink in regional Earth system dynamics

Continued warming of the Arctic will likely accelerate terrestrial carbon (C) cycling by increasing both uptake and release of C. Yet, there are still large uncertainties in modelling Arctic terrestrial ecosystems as a source or sink of C. Most modelling studies assessing or projecting the future fate of C exchange with the atmosphere are based on either stand-alone process-based models or coupled

Thermomechanical optimization of lightweight thermal protection system under aerodynamic heating

An optimization procedure has been established aiming to design an integrated thermal protection system (ITPS) with minimum weight. The objective of this research is to establish the procedure and ensure its effectiveness. A corrugated sandwich panel has been chosen as the optimization problem. The ITPS geometric dimensions are considered as the design variables. The objective function is the mass

Consumption of predefined 'Nordic' dietary items in ten European countries - an investigation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Health-beneficial effects of adhering to a healthy Nordic diet index have been suggested. However, it has not been examined to what extent the included dietary components are exclusively related to the Nordic countries or if they are part of other European diets as well, suggesting a broader preventive potential. The present study describes the intake of seven a priori defined healthy food items (

Leading edge vortices in lesser long-nosed bats occurring at slow but not fast flight speeds.

Slow and hovering animal flight creates high demands on the lift production of animal wings. Steady state aerodynamics is unable to explain the forces required and the most commonly used mechanism to enhance the lift production is a leading edge vortex (LEV). Although LEVs increase the lift, they come at the cost of high drag. Here we determine the flow above the wing of lesser long-nosed bats at

Geographical variation and systematics of the tetraploid marsh orchid Dactylorhiza majalis subsp sphagnicola (Orchidaceae) and closely related taxa

Dactylorhiza majalis subsp. sphagnicola is an allotetraploid marsh orchid derived from parents closely similar to present-day D. incarnata and the western European form of D. maculata subsp. maculata, suggesting that it has a postglacial origin. It extends from northwestern continental Europe into areas formerly covered by the Weichselian ice sheet in mid-Scandinavia. Here, we studied the variatio

Cooperativity, Local-Nonlocal Coupling, and Nonnative Interactions: Principles of Protein Folding from Coarse-Grained Models

Coarse-grained, self-contained polymer models are powerful tools in the study of protein folding. They are also essential to assess predictions from less rigorous theoretical approaches that lack an explicit-chain representation. Here we review advances in coarse-grained modeling of cooperative protein folding, noting in particular that the Levinthal paradox was raised in response to the experimen

The drumlin field and the geomorphology of the Mulajokull surge-type glacier, central Iceland

Here we present a new geomorphological map of the active drumlin field and the forefield of Millajokull, a surgetype outlet glacier, Iceland. The map is based on aerial photographs taken in 1995 and LiDAR data recorded in 2008. Mapping was done using ArcGIS 10 software on orthorectified imagery, LiDAR data and digital elevation models. The mapped landforms were initially identified on the aerial i

[F-18]Fluorodeoxyglucose - positron emission tomography/computed tomography improves staging in patients with high-risk muscle-invasive bladder cancer scheduled for radical cystectomy

Objective. The aim of this study was to evaluate the clinical use of [F-18]-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in addition to conventional preoperative radiological investigations in a defined group of patients with high-risk muscle-invasive bladder cancer. Materials and methods. In total, 103 patients with high-risk muscle-invasive bladder cancer defi

Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis

Background: Interactions between Th1 and Th2 immune responses are of importance to the onset and development of allergic disorders. A Toll-like receptor 7 agonist such as AZD8848 may have potential as a treatment for allergic airway disease by skewing the immune system away from a Th2 profile. Objective: To evaluate the efficacy and safety of intranasal AZD8848. Methods: In a placebo-controlled si

Properties of jets measured from tracks in proton-proton collisions at center-of-mass energy root s=7 TeV with the ATLAS detector

Jets are identified and their properties studied in center-of-mass energy root s = 7 TeV proton-proton collisions at the Large Hadron Collider using charged particles measured by the ATLAS inner detector. Events are selected using a minimum bias trigger, allowing jets at very low transverse momentum to be observed and their characteristics in the transition to high-momentum fully perturbative jets

Slide-based ergometer rowing: Effects on force production and neuromuscular activity.

Force production profile and neuromuscular activity during slide-based and stationary ergometer rowing at standardized submaximal power output were compared in 14 male and 8 female National Team rowers. Surface electromyography (EMG) was obtained in selected thoracic and leg muscles along with synchronous measurement of handle force and rate of force development (RFD). Compared to stationary condi

Corroboration of computational models for mechanoregulated stem cell differentiation

Do computational models contribute to progress in mechanobiology? Jacobs and Kelly (in Advances on Modelling in Tissue Engineering, p. 1–14, 2011) suggest that they do, but at the same time propose a limitation in the form of the ‘paradox of validation’, whereby the information needed to validate mechanoregulation theories obviates the need for them in the first place. In this article, the corrobo

Nature of flocculation and tactoid formation in montmorillonite: the role of pH.

The dissolution and swelling properties of montmorillonite at different pH have been studied, using small angle X-ray scattering (SAXS), imaging and osmotic stress methods combined with Monte Carlo simulations. The acidity of montmorillonite dispersions has been varied as well as the counterions to the net negatively charged platelets. At low pH, Na montmorillonite dissolves and among other specie

Atrial aspiration from pulmonary and caval veins is caused by ventricular contraction and secures 70% of the total stroke volume independent of resting heart rate and heart size.

Whereas ventricular filling has been extensively studied and debated, atrial filling is less well characterized. Therefore, the aim of this study was to quantify atrial filling secured during ventricular diastole and systole, and to investigate whether atrial filling depends on heart rate (HR) and total heart volume (THV).

Full Spectrum of Psychiatric Disorders Related to Foreign Migration A Danish Population-Based Cohort Study

Importance: Although increased risk for schizophrenia among immigrants is well established, knowledge of the broader spectrum of psychiatric disorders associated with a foreign migration background is lacking. Objective: To examine the full range of psychiatric disorders associated with any type of foreign migration background among persons residing in Denmark, including foreign-born adoptees, fir