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Educational Psychology in Europe

Today, Russia is a member of the European Federation of Psychological Associations (EFPA) and in the summer 2019 the Russian Psychologi- cal Society was the host to the 16th European Congress of Psychology (ECP) in Moscow, gathering psychologists from all over the world. In connection with the 2019 ECP, this special edition has been compiled by members of EFPA’s Standing Committee on Psychology in

Toward a Reasons-First View of Normative Background Conditions

Background conditions are thought to explain how objects can have value in virtue of certain features and how reasons can consist in certain facts. The following paper provides an account of what background conditions are and what effect they have on normative features. It defends the idea that if values depend on reasons, then there is nothing really surprising or mysterious about the presence of

Hierarchies and entrepreneurship

We establish a correlation between the hierarchical structure of a firm and the likelihood of business creation among its former employees, using a sample of 16 million observations of Swedish workers and a novel proxy for hierarchies based on occupation data. Conditional on firm size and many other variables, employees in firms with more layers are less likely to enter entrepreneurship, to become

The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products

Precise regulation of dNTPs within the cellular nucleotide pool is essential for high accuracy of DNA replication and is critical for retaining the genomic integrity. Recently, human dCTPase (deoxycytidine triphosphatase), also known as DCTPP1 (human all-alpha dCTP pyrophosphatase 1) has been revealed to be a key player in the balance of pyrimidine nucleotide concentrations within cells, with DCTP

Quality Improvement Initiatives in Fragility Fracture Care and Prevention

Purpose of Review: This review sought to describe quality improvement initiatives in fragility fracture care and prevention. Recent Findings: A major care gap persists throughout the world in the secondary prevention of fragility fractures. Systematic reviews have confirmed that the Fracture Liaison Service (FLS) model of care is associated with significant improvements in rates of bone mineral de

Understanding and Modulating Immunity With Cell Reprogramming

Cell reprogramming concepts have been classically developed in the fields of developmental and stem cell biology and are currently being explored for regenerative medicine, given its potential to generate desired cell types for replacement therapy. Cell fate can be experimentally reversed or modified by enforced expression of lineage specific transcription factors leading to pluripotency or attain

Water channel pore size determines exclusion properties but not solute selectivity

Aquaporins (AQPs) are a ubiquitous family of transmembrane water channel proteins. A subgroup of AQP water channels also facilitates transmembrane diffusion of small, polar solutes. A constriction within the pore, the aromatic/arginine (ar/R) selectivity filter, is thought to control solute permeability: previous studies on single representative water channel proteins suggest narrow channels condu

Political connection and disconnection : Still a success factor for Chinese Entrepreneurs

Political connection in China is often tested for correlation with business success and government support under a suspicion that connected entrepreneurs enjoy special favors and protection. Research evidence is mixed. In revisiting the debate on political capital in China, we apply a socially embedded perspective on political connection. To this end we introduce two methodological innovations: (a

Inhomogeneous potentials, Hausdorff dimension and shrinking targets

Generalising a construction of Falconer, we consider classes of 𝐺𝛿-subsets of ℝ𝑑 with the property that sets belonging to the class have large Hausdorff dimension and the class is closed under countable intersections. We relate these classes to some inhomogeneous potentials and energies, thereby providing some useful tools to determine if a set belongs to one of the classes

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

Lysine methylation is abundant on histone proteins, representing a dynamic regulator of chromatin state and gene activity, but is also frequent on many non-histone proteins, including eukaryotic elongation factor 1 alpha (eEF1A). However, the functional significance of eEF1A methylation remains obscure and it has remained unclear whether eEF1A methylation is dynamic and subject to active regulatio

Determinants of Wealth Inequality and Mobility in General Equilibrium

What determines inequality and mobility of wealth? This paper quantifies in closed form both the bottom and the top (Pareto) tail of the distribution for a rich continuous-time model. The distribution is especially shaped by bequest motives, demographics, and the asset portfolio composition under idiosyncratic wealth risk. Factors that increase inequality also reduce mobility. The model - enriched

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and International Lung Cancer Consortium (29,266 cases, 56,450 controls) shows that lung cancer is genetically correlated with reduced forced expiratory volume in one second (FEV1: r

Auralization as a tool of historic reconstruction of Vadstena Abbey church

Throughout human history, there have been locations used for performance of speech and music. Many of these locations are considered part of our common cultural heritage, and more and more of them can be visited virtually as technology advances to produce better and better reconstructions. However, the technological capabilities are not the only limitations when it comes to historical reconstructi