Search results

Filter

Filetype

Your search for "*" yielded 540009 hits

The impact of smoking on inhaled insulin.

OBJECTIVE—This study, one of the first to address issues of pulmonary insulin delivery in smokers, compared pharmacokinetics of inhaled insulin delivered via the AERx insulin Diabetes Management System (iDMS) in nondiabetic cigarette smokers and nonsmokers. RESEARCH DESIGN AND METHODS—In this randomized two-period crossover efficacy and safety trial in 27 nondiabetic smokers and 16 nonsmokers (18

Adding realism to simulated measurements and actuators

In this paper, we propose a statistical theoretical framework for incorporation of sensor and actuator faults in dynamic simulations of wastewater treatment operation. Sensor and actuator faults and failures are often neglected in simulations for control strategy development and testing, although it is well known that they represent a significant obstacle for realising control at full-scale facili

Sampling rate and the estimation of ensamble variability for repetive signals

The measurement of ensemble variability in time-aligned event signals is studied in relation to sampling rate requirements. The theoretical analysis is based on statistical modelling of time misalignment in which the time resolution is limited by the length of the sampling interval. For different signal-to-noise ratios (SNRs), the sampling rate is derived which limits the misalignment effect to le

Antibody orientation at bacterial surfaces is related to invasive infection.

Several of the most significant bacterial pathogens in humans, including Streptococcus pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable (Fc) region, and the dogma is that this protects the bacteria against phagocytic killing in blood. However, analysis of samples from a patient with invasive S. pyogenes infection revealed dramatic differences in the pre

The experience of empowerment in the patient-staff encounter: the patient's perspective.

Aim and objective. The aim was to explore empowerment within the patient-staff encounter as experienced by out-patients with chronic kidney disease. Background. Empowerment has an important role to play in the patient-staff relationship in the case of patients with a chronic disease. When it comes to patients with chronic kidney disease, there has been little research on empowerment, for which rea

Hoarseness as a Sign of Possible Nonspecific Mucosal Hyperreactivity in Vocal Tract.

The aim of the present paper was to evaluate the possible impact of methacholine challenge on the voice and vocal tract in 10 patients reporting hoarseness due to presumable hyperreactivity to some environmental factors. Ten age and gender-matched healthy subjects served as controls. Methacholine was used for hypersensitivity challenge and saline solution (0.9% NaCl) as control substance. Subjects

Structural Retrofitting of Reinforced Concrete Beams using Carbon Fibre Reinforced Polymer

This thesis details experimental work and finite element simulations of reinforced concrete beams retrofitted with carbon fibre reinforced polymer (CFRP). The objectives of this study were to investigate the behaviour of retrofitted beams experimentally, develop a finite element model describing the beams, verifying the finite element model against the experimental results and finally investigatin

Combustion Chamber Wall Temperature Measurement and Modeling During Transient HCCI Operation

In this paper the combustion chamber wall temperature was measured by the use of thermographic phosphor. The temperature was monitored over a large time window covering a load transient. Wall temperature measurement provide helpful information in all engines. This temperature is for example needed when calculating heat losses to the walls. Most important is however the effect of the wall tempera

Rho-kinase signalling regulates trypsinogen activation and tissue damage in severe acute pancreatitis.

Background and purpose: Severe acute pancreatitis (SAP) is characterized by trypsinogen activation, infiltration of leucocytes and tissue necrosis but the intracellular signalling mechanisms regulating organ injury in the pancreas remain elusive. Rho-kinase is a potent regulator of specific cellular processes effecting several pro-inflammatory activities. Herein, we examined the role of Rho-kinase