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Green chemistry in perspective - models for GC activities and GC policy and knowledge areas

This article presents two new models that give a perspective on green chemistry (GC). The first model is a classification model of different green chemistry activities, while the second model concerns green chemistry policy and knowledge areas (green chemistry principles, industrial biotechnology and "the green sector"). A broad view of green chemistry is used, where all activities with the aim of

CO2-free power generation in combined cycles - Integration of post-combustion separation of carbon dioxide in the steam cycle

Ever since the release of the Kyoto protocol the demand for CO2-free processes have been increasing. One of the most expanding sources of electric power in the industrialised world today is the gas-fired combined cycle, combining high efficiency and low investment cost. In this paper, the integration of a post-combustion CO2-separation unit into a combined cycle is studied from a thermodynamic and

Driving to learn: powered wheelchair training for those with cognitive disabilities

The Driving to Learn project was an exploration of how those with significant cognitive disabilities could benefit from training in a joystick-operated powered wheelchair. This study focuses on a particular part of the wider Driving to Learn project, mainly looking at the relationship between characteristics connected to powered wheelchair-use and the trainees' success or failure in developing a c

Love thy neighbour? Social nesting pattern, host mass and nest size affect ectoparasite intensity in Darwin’s tree finches

Social nesting behaviour is commonly associated with high prevalence and intensity of parasites in intraspecific comparisons. Little is known about the effects of interspecific host breeding density for parasite intensity in generalist host–parasite systems. Darwin’s small tree finch (Camarhynchus parvulus) on Santa Cruz Island, Galápagos Islands, nests in both heterospecific aggregations and at s

Total antioxidant capacity and content of flavonoids and other phenolic compounds in canihua (Chenopodium pallidicaule): An Andean pseudocereal

Total antioxidant capacity (TAC), total phenolic compounds (TPH), total flavonoids (TF) and individual phenolic compounds were determined in canihua collected at approx. 3850 in altitude. The TAC values varied among samples from 2.7 to 44.7 by the ferric reducing antioxidant power (FRAP) method and from 1.8 to 41 by the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) method expresse

The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer.

dentification and characterization of the genetic background in patients with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome is important since control programmes can in a cost-effective manner prevent cancer development in high-risk individuals. HNPCC is caused by germline mismatch repair (MMR) gene mutations and the genetic analysis of HNPCC therefore includes assessment of micro

Paperboard packages exposed to static loads–finite element modelling and ­experiments

The aim of this study was to analyse the mechanical behaviour of paperboard packages subjected to static compressive loads. The study was divided in three parts and experiments and finite element analysis conducted for each part. First, a panel of paperboard was subjected to edge compressive loading as a means of checking the material model. Second, the package was cut into segments and each segme

Methodology for close up studies - struggling with closeness and closure

The paper critically reviews some themes and methods within qualitative research and argues for self-ethnography as an approach to study universities and other settings which the researcher is highly familiar with, and has direct access to. Advantages and disadvantages are discussed. In particular the struggle between utilizing closeness to empirically rich situations and avoid the closure followi

In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner

IgG antibodies are potent inducers of proinflammatory responses. During autoimmune diseases such as arthritis and systemic lupus erythematosus, IgG autoantibodies are responsible for the chronic inflammation and destruction of healthy tissues by cross-linking Fc receptors on innate immune effector cells. The sugar moiety attached to the asparagine-297 residue in the constant domain of the antibody

Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United States

The age-adjusted incidence of multiple myeloma (MM) is 2-fold higher in African Americans than in whites. A few small studies have reported a higher prevalence of monoclonal gammopathy of undetermined significance (MGUS) in African Americans versus whites. Etiologic factors for MGUS and determinants for transformation of MGUS to MM are unknown. We quantified the prevalence of MGUS and subsequent r

Absence of phosphoglucose isomerase-1 in retinal photoreceptor, pigment epithelium and Muller cells

Macroarray analysis was used to compare equal amounts of cDNA from wild-type and rd/rd (retinal degeneration) mice, collected at P90 when photoreceptor degeneration is virtually complete. A stronger signal for the glycolytic enzyme phosphoglucose isomerase (Gpi1) was observed in the rd/rd sample. Extracellularly, Gpi1 may act as a cytokine, independently described as neuroleukin and autocrine moti

Structure of muramic acid TMS derivative mass spectrum's base ion (m/z=185) used for quantification of bacterial peptidoglycan.

The use of trimethylsilyl (TMS)-derivatisation for determining muramic acid in environmental and clinical samples by gas chromatography-mass spectrometry provides high detection sensitivity; however, questions have been raised as concerns the chemical structure of the entity giving the strong signal of m/z 185. In the present communication we present evidence that this entity results from the form

Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury.

Rho-kinase signaling regulates important features of inflammatory reactions. Herein, we investigated the effect and mechanisms of action of the Rho-kinase inhibitor fasudil in endotoxemic liver injury. C57/BL/6 mice were challenged with lipopolysaccharide (LPS) and D-galactosamine, with or without pretreatment with the Rho-kinase inhibitor fasudil. Six hours after endotoxin challenge, leukocyte-en

Understanding prediction systems for HLA-binding peptides and T-cell epitope identification

Peptide binding to HLA molecules is a critical step in induction and regulation of T-cell mediated immune responses. Because of combinatorial complexity of immune responses, systematic studies require combination of computational methods and experimentation. Most of available computational predictions are based on discriminating binders from non-binders based on use of suitable prediction threshol

Effect of propofol on isolated human omental arteries and veins

To elucidate the effect and mode of action of propofol on human vascular smooth muscle tension, we have investigated the effect of propofol alone and the effect of propofol on contractions induced by U46619, KCl and caffeine on isolated human omental vessels. Propofol 10(-3) mol litre-1 induced contractions in both arteries and veins attenuated the contraction elicited by U46619, KCl and caffeine

The gene encoding protein D (hpd) is highly conserved among Haemophilus influenzae type b and nontypeable strains

The molecular conservation of a surface-exposed lipoprotein, protein D, of Haemophilus influenzae was studied by cloning and sequencing of the gene encoding protein D from three encapsulated type b strains and three nontypeable strains of H. influenzae. These nucleotide sequences were analyzed with previously reported sequences from one type b strain and one nontypeable strain. The nucleotide sequ

Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination

Background. Several clinical studies have suggested possible increase in cardiovascular risk during and in the first weeks after an acute inflammatory disease. Using influenza vaccine as inflammatory stimulus, we investigated whether arterial endothelial dysfunction could persist beyond the inflammatory state, and whether amplified oxidative modification of low-density lipoprotein (LDL) accompanie

Fluctuations and Fermi-Dirac Correlations in e(+)e(-)-annihilation

In this talk I first present a short review of fluctuations in e (+) e(-) -annihilations. I then describe some new results on FD correlations. Experimental analyses of pp and Lambda Lambda correlations indicate a very small production radius. This result relies very strongly on comparisons with MC simulations. A study of the approximations and uncertainties in these simulations implies that it is