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Purpose – This paper aims to contribute to the tactical and operational decision making of manufacturing and logistics operations by providing novel insights into modelling and simulation, based on complex adaptive systems (CAS). Design/methodology/approach – The research approach is theoretically based on CAS with agent-based modelling (ABM) as the implementation method. A case study is presented

Although very often used, the concept of sustainable development has not yet been perceived pragmatically. Due to its process nature, in this paper, we argue that sustainable development is a process in which the essential feedback loops, or Viability Loops as we name them, in the system in question are kept healthy and functional. This process deals with evolutionary changes with the end point no

The dry reaction between SO2 and limestone has been investigated at low temperatures. The study was focused on the wet-dry scrubbing application. Parameters investigated included: temperature: 313–353 K, SO2 concentration: 50–4000 ppm, oxygen concentration: 0–9 percent, carbon dioxide concentration: 0–10 percent, relative humidity 0–92 percent, limestone panicle diameter: 4–100 microns, and limest

In this paper, the transversal diffusion coefficient D of CO2 dissolved molecules through the wall of a hydrated cellulose fiber was approached, from the liquid bulk diffusion coefficient of CO2 dissolved molecules modified by an obstruction factor. The porous network between the cellulose microfibrils of the fiber wall was assumed being saturated with liquid. We retrieved information from previou

Two-particle correlations of direct photons were measured in central (208Pb+208Pb collisions at 158A GeV. The invariant interferometric radii were extracted for 100

All guidelines recommend short-acting inhaled beta 2-adrenoceptor agonists as the first-line drugs in acute asthma attacks and inhaled corticosteroids as the drugs of choice when regular daily treatment is needed. Short-acting inhaled beta 2-adrenoceptor agonists are not effective in reducing nocturnal awakenings because of their short duration of action. In addition there has been an intense deba

The post-burn immune dysfunction predisposes patients to sepsis and multiple organ failure leading to increased mortality. HIV infection also results in a depressed immune response. The combination of burn injury and HIV might therefore lead to an increased morbidity and mortality as compared to non-HIV infected burn patients. Twenty burn patients and 10 healthy volunteers were included in a prosp

Today embedded control systems are created using tools that give insufficient support for rapid prototyping and code reuse. New tools for the implementation of embedded controllers are necessary. This paper presents the experimental software framework Palsjo, and the language PAL. The Palsjo system is a rapid prototyping environment designed to support on-line system reconfigurations and code reus

Single-channel currents were activated by THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) in cell-attached patches on CA1 pyramidal neurons in the rat hippocampal slice preparation. THIP activated GABA(A) channels after a delay that was concentration-dependent and decreased by 1 muM diazepam. The currents showed outward rectification. Channels activated at depolarized 40 mV relative to the c

Asthma is an increasingly common disorder, affecting 5-10% of the population. It involves a dysregulated immune function, which may predispose to subsequent cancer. We examined cancer risk among Swedish subjects who had hospital admission once or multiple times for asthma. An asthma research database was created by identifying asthma patients from the Swedish Hospital Discharge Register and by lin

Objectives This study assessed paternal occupational exposure to di(2-ethylhexyl)phthalate (DEHP) in association with reduced fertility. Methods Men working in three plants with DEHP exposure were studied retrospectively. Male and female employees and their partners were invited to participate if they had reported a pregnancy or an attempt to achieve a pregnancy. Postal questionnaires and telephon

Production of high-amylose potato lines can be achieved by inhibition of two genes coding for starch branching enzymes. The use of antisense technology for gene inhibition have yielded a low frequency of high-amylose lines that mostly was correlated with high numbers of integrated T-DNA copies. To investigate whether the production of high-amylose lines could be improved, RNA interference was used

Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily affecting cartilaginous joints but also extra-articular tissues such as the nose and upper respiratory tract. We have investigated extra-articular cartilage involvement in two commonly used animal models for RA, collagen-induced and pristane-induced arthritis, by immunizing rats with different susceptibility to disease (LEW.1 A,

The complementary employment of two separation techniques, one analytical-scale, the other preparative-scale, i.e. the lift-hyperlayer asymmetrical flow field-flow fractionation (AsyFIFFF) and the split flow-thin cell (SPLITT) is presented for the first time as a methodology to size-separate and rapidly characterize starch granules of different botanical origins. Very rapid separation and size cha

The effect of the application of pulsed electric fields to potato tissue on the diffusion of the fluorescent dye FMI-43 through the cell wall was studied. Potato tissue was subjected to field strengths ranging from 30 to 500 V/cm, with one 1 ms rectangular pulse, before application of FM1-43 and microscopic examination. Our results show a slower diffusion of FM1-43 in the electropulsed tissue when