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Measurement of the parity-violating asymmetry parameter ab and the helicity amplitudes for the decay Lambda(0)(b) -> J/psi Lambda(0) with the ATLAS detector

A measurement of the parity-violating decay asymmetry parameter, ab, and the helicity amplitudes for the decay.Lambda(0)(b) -> J/psi(mu(+) mu(-)) Lambda(0)(p pi(-)) is reported. The analysis is based on 1400 Lambda(0)(b)and (Lambda) over bar (0)(b) baryons selected in 4.6 fb(-1) of proton-proton collision data with a center-of-mass energy of 7 TeV recorded by the ATLAS experiment at the LHC. By co

Gap metrics for time-varying linear systems in a continuous-time setting

A recently proposed time-varying generalisation of Vinnicombe's v-gap is shown to have the properties of a metric on a class of causal linear continuous-time systems that admit normalised strong graph representations. An alternative time-varying gap metric is then defined in more general terms and a corresponding robust stability result is derived for linear feedback interconnections. Finally, it

Topical non-peptide antagonists of sensory neurotransmitters substance P and CGRP do not modify patch test and prick test reactions: a vehicle-controlled, double-blind pilot study.

Immunologic responses in the skin can be modulated by such neurotransmitters of sensory nerve fibers as substance P (SP) and calcitonin gene-related peptide (CGRP). The first-generation receptor antagonists were peptides with large molecules and had to be injected intracutaneously. The aim of this study was to examine the topical effects of non-peptide antagonists to substance P (aprepitant) and C

Multiplexed MALDI-MS arrays for screening of MIP solid phase extraction materials.

Technology that facilitates rapid investigation of solid phase extraction protocols using very small amounts of sorbent can save both time and money. The microfabricated ISET (Integrated Selective Enrichment Target) interfaced with MALDI mass spectrometry is able to provide an efficient, economic and generic optimization process for SPE sample preparation. The SPE is performed in a rapid and paral

Solitary living in Alzheimer's disease over 3 years: association between cognitive and functional impairment and community-based services.

Introduction: Many individuals with Alzheimer’s disease (AD) live alone, and this figure is expected to increase. This study aimed to describe the cognitive and functional abilities of solitary-living AD patients, and the potential predictors of their usage of community-based services. Methods: This 3-year, prospective, multicenter study included 1,021 participants with mild-to-moderate AD (Mini-M

Viewing child pornography: Prevalence and correlates in a representative community sample of young Swedish men

Most research on child pornography use has been basedonselected clinical or criminal justice samples;riskfactors for child pornography use in the general population remain largely unexplored. In this study, we examined prevalence, risk factors,andcorrelates of viewingdepictions of adult–child sex in a population-representative sample of 1,978 young Swedish men(17–20 years,Mdn=18 years, overall res

Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer.

Toll-like receptors (TLRs) are a family of pattern recognition receptors that are expressed on cells of the innate immune system. The ligands can be pathogen derived (pathogen associated molecular patterns; PAMPs) or endogenous (damage associated molecular patters; DAMPs) that when bound induces activation of nuclear factor kappa B (NF-κB) and transcription of pro-inflammatory genes. TLRs have als

Changes in bleeding patterns in von Willebrand disease after institution of long-term replacement therapy: results from the von Willebrand Disease Prophylaxis Network.

Clinically, the leading symptom in von Willebrand disease (VWD) is bleeding, chiefly of mucosal type, for example, epistaxis, gingival, or gastrointestinal bleeding, and menorrhagia. In severe forms of VWD with secondary deficiency of factor VIII, spontaneous joint bleeding, resembling that observed in severe haemophilia A, may also be observed. The bleeding patterns of VWD can affect quality of l

Measurement of transverse single-spin asymmetries for J/psi production in polarized p plus p collisions at root s=200 GeV

We report the first measurement of transverse single-spin asymmetries in J/psi production from transversely polarized p + p collisions at root s = 200 GeV with data taken by the PHENIX experiment in 2006 and 2008. The measurement was performed over the rapidity ranges 1.2 < vertical bar y vertical bar < 2.2 and vertical bar y vertical bar < 0.35 for transverse momenta up to 6 GeV/c. J/psi producti

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.

Ebf1 is a transcription factor with documented dose dependent functions in normal and malignant B-lymphocyte development. To understand more about the roles of Ebf1 in malignant transformation, we investigated the impact of reduced functional Ebf1 dosage on mouse B-cell progenitors. Gene expression analysis suggested that Ebf1 was involved in the regulation of genes important for DNA repair as wel

Exposure to peer deviance during childhood and risk for drug abuse: a Swedish national co-relative control study.

Background. Peer deviance (PD) is associated with risk for drug abuse (DA). Is this association causal? Method. DA was recorded in official records. PD was defined as the percentage of peers residing in small communities with future DA registrations. We examined offspring in families whose community PD changed when the offspring was 0-15 years of age and then examined families where cousins or sib

Semiconductor-Oxide Heterostructured Nanowires Using Postgrowth Oxidation.

Semiconductor-oxide heterointerfaces have several electron volts high-charge carrier potential barriers, which may enable devices utilizing quantum confinement at room temperature. While a single heterointerface is easily formed by oxide deposition on a crystalline semiconductor, as in MOS transistors, the amorphous structure of most oxides inhibits epitaxy of a second semiconductor layer. Here, w

Sex differences in telomere selection in the wild

Telomere length is restored primarily through the action of the reverse transcriptase telomerase, which may contribute to a prolonged lifespan in some but not all species and may result in longer telomeres in one sex than the other. To what extent this is an effect of proximate mechanisms (e.g. higher stress in males, higher oestradiol/oestrogen levels in females), or is an evolved adaptation (str

Effect of direction of approach of test temperature on fracture toughness of Zr-2.5Nb pressure tube material

Previous work by one of the authors reported the stress-field for a fully-constrained hydride embedded in matrix computed using finite element method to develop an understanding of the temperature dependence of susceptibility of Zr-alloys to hydride embrittlement. It was observed that the nature and magnitude of stress field in the matrix and hydride depended on whether the hydride is expanding (e

Relocating the owl of wisdom : Encyclopaedias in a life-historical perspective

Artikeln undersöker människors förhållningssätt till uppslagsverk och encyklopedier i ett livshistoriskt perspektiv under en period när encyklopedier har genomgått dramatiska förändringar. En frågelista som skickats till fasta så kallade meddelare knutna till Folklivsarkivet i Lund har använts som metod. Svaren har analyserats med hjälp av posthumanistisk teori. Analysen visar de sätt som tryckta Encyclopaedias are artefacts that both define and are defined by the culture in which they are produced and used. Encyclopaedias mirror the time of their creation, at the same time as understanding and use of encyclopaedias is tied to both time and space. From the 19th century until the present day encyclopaedias have changed from exclusive and costly Collections of books kept mainly in libraries

In Vitro Blood-Brain Barrier Models-An Overview of Established Models and New Microfluidic Approaches.

The societal need for new central nervous system (CNS) medicines is substantial, because of the global increase in life expectancy and the accompanying increase in age-related CNS diseases. Low blood-brain barrier (BBB) permeability has been one of the major causes of failure for new CNS drug candidates. There has therefore been a great interest in cell models, which mimic BBB permeation propertie

Costs and quality of life in multiple sclerosis patients with spasticity.

BACKGROUND: The resource use and health-related quality of life (HRQoL) of patients with multiple sclerosis (MS) spasticity are not well known. The purpose of this study was to obtain estimates of resource utilization, costs, and HRQoL, for patients with different levels of MS spasticity in southern Sweden. MATERIAL AND METHODS: Cross-sectional data on spasticity severity (using a Numerical Rating