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Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity

ATP-sensitive K(+) channels (K(ATP) channels) of pancreatic beta-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and decrease channel sensitivity to ATP inhibition; as such, they have been postulated as critical regulat

Amplitude-integrated encephalography in pyridoxine-dependent seizures and pyridoxine-responsive seizures.

Pyridoxine-dependent seizures are rare in newborn infants, although recent data suggest that the prevalence probably is underestimated. In all newborn infants with recurrent epileptic seizures the general recommendation is to administer pyridoxine and simultaneously record an electroencephalogram (EEG). Conclusion: One infant with pyridoxine-responsive seizures and another with pyridoxine-dependen

Modelling the vegetation of China using the process-based equilibrium terrestrial biosphere model BIOME3

1 We model the potential vegetation and annual net primary production (NPP) of China on a 10' grid under the present climate using the processed-based equilibrium terrestrial biosphere model BIOME3. The simulated distribution of the vegetation was in general in good agreement with the potential natural vegetation based on a numerical comparison between the two maps using the DeltaV statistic (Delt

Ballaststudier

Innehåll: Forskningsbehov inom ballastområdet; Lättballast ; Ballastens funktion i betong ; Testmetoder och kvalitetskriterier för ballast till betong

Numerisk simulering av detektionsmiljö med fältmodeller

För att kunna beräkna tiden till aktivering av en rökdetektor krävs en beskrivning av strömnings- och temperaturförhallandena samt röktätheten i detektorns omgivning. Den transienta utvecklingen av strömnings-, temperatur- och koncentrationsförhållandena i ett rum med en brandkälla och av godtycklig geometri kan simuleras med hjälp av sk fältmodeller. I denna rapport presenteras resultaten fran en

The interaction between PEO-PPO-PEO triblock copolymers and ionic surfactants in aqueous solution studied using light scattering and calorimetry

Properties of nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (EOnPOmEOn) in aqueous solution and their interaction with the ionic surfactants sodium dodecyl sulfate and hexadecyltrimethylammonium chloride have been investigated by static and dynamic light scattering, high sensitivity differential scanning, and isothermal titration calorimetry. The studie

Police Persuasion: Making Battered Women File a Complaint

A common theme in sociological literature on "domestic violence" is that police officers view such cases as private problems and not as objects for proper policework. Thus, it is argued that police officers interactionally discourage arrest in domestic disturbance cases. In an etnographic study of Swedish police officers, however, police officers, instead of discouraging arrest or filing of compl

Abnormal retinal vascular morphology in young adults following intrauterine growth restriction

Objective. Intrauterine growth restriction ( IUGR) resulting in low birth weight for gestational age may predispose one to development of cardiovascular disease later in life. Abnormal fetal blood flow in the presence of fetal growth restriction helps to distinguish infants with true fetal growth impairment from small but normal infants. Our goal was to investigate associations between IUGR with a

Osmotic-treatment-induced cell death and osmotic processing kinetics of apples with characterised raw material properties

Three apple varieties cultivated in southern Sweden namely Jonagold, Kim and Mutsu were subjected to osmotic treatment at 5, 20 and 40 degreesC with a 50% sucrose solution. The evaluation of cell viability after osmotic processing, was carried out in Granny Smith apples from Argentina. The processing conditions were 50% sucrose solution at 20 degreesC and the viability assay used was based on the