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DNA ploidy analysis in breast carcinoma. Comparison of unfixed and fixed tissue analyzed by image and flow cytometry

OBJECTIVE: To form a methodologic basis for DNA analysis of ductal carcinoma in situ (DCIS) and invasive carcinoma (IC) of the breast, including very small lesions, by comparison of flow cytometric (FCM) and image cytometric (ICM) methods for DNA quantitation. STUDY DESIGN: The material consisted of 41 DCIS lesions and 26 ICs. FCM DNA analysis of unfixed, frozen samples were compared to (1) FCM of

Individual and contextual determinants of self-reported poor psychological health: A population-based multilevel analysis in southern Sweden.

Objective: To investigate the influence of contextual and individual factors on self-reported psychological health. Design/setting/participants/measurements: The 2000 public health survey in Scania is a cross-sectional postal questionnaire study with a 59% participation rate. A total of 13,715 persons aged 18-80 answered the questionnaire. A multilevel logistic regression model, with individuals a

Nodule detection in digital chest radiography: Introduction to the radius chest trial

Most digital radiographic systems of today have wide latitude and are hence able to provide images with a small constraint on dose level. This opens up for an unprejudiced dose optimisation. However, in order to succeed in the optimisation task, good knowledge of the imaging and detection processes is needed. As a part of the European-wide research project 'unification of physical and clinical req

Fuktsäkerhet i byggnader : generell metod för fuktdimensionering av byggnader

Två tillämpningsexempel visar att den beskrivna fuktdimensioneringsmetoden är praktiskt genomförbar både när det gäller övergripande anvisningar (s k generella checklistor) för olika byggnadsdelar och för exakt definierade kontrollpunkter för en enskild byggnadsdelar (s k projekteringschecklista som redovisar ett oventilerat varmtak med papp eller dukar av gummi eller plast). De anvisningar som fi

Pain and quality of life among older people with rheumatoid arthritis and/or osteoarthritis: a literature review.

The aim of this study was to review the research literature on pain and quality of life (QoL) and the relationship between these variables among people aged 75 years and above with rheumatoid arthritis and/or osteoarthritis. A Medline and CINAHL search was carried out using MeSH terms rheumatoid arthritis, osteoarthritis, QoL and pain in various combinations. Seventeen articles were identified tha

Rigidity of the Doubly-Magic 100Sn Core

The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei are by themselves ver

Modelling the fate of ultrafine particles from exhaust pipe to rural background: an analysis of time scales for dilution, coagulation and deposition

We investigate the time scales of various dynamic processes during the evolution of the particle size distribution from its emission from a vehicle exhaust pipe through its dilution at kerbside and urban level. In addition, the situation in a road tunnel or near a highway is discussed. The derived formula framework allows the estimation of approximated time scales based on a given particle size di

Activities of daily living decrease similarly in hospital-treated patients with a hip fracture or a vertebral fracture: a one-year prospective study in 151 patients

Aims: A hip fracture is commonly regarded as the most devastating fragility fracture, as regards both morbidity and mortality, while a vertebral fracture is usually regarded as having lower general morbidity. The purpose of this study was to investigate whether hospitalized patients with a hip or a vertebral fracture experience similar functional deterioration following the fracture as regards act

Effect of a conjugated carbonyl group on the photophysical properties of carotenoids

Effects of introducing a carbonyl group into the conjugation system of carotenoids were studied for four naturally occurring carotenoids: peridinin, fucoxanthin, siphonaxanthin and spheroidenone. The conjugated carbonyl group affects energetics and dynamics of all these carotenoids in a similar way, although the magnitude of the changes depends strongly on the carotenoid structure. Firstly, presen

Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis

Background-Accumulation and oxidation of LDL are believed to be important initiating factors in atherosclerosis. Oxidized LDL is recognized by the immune system, and animal studies have suggested that these immune responses have a protective effect against atherosclerosis. Aldehyde-modified peptide sequences in apolipoprotein B-100 (apoB-100) are major targets for these immune responses. Methods a

Regular Grobner bases

In this paper we introduce the concept of bi-automaton algebras, generalizing the automaton algebras previously defined by Ufnarovski. A bi-automaton algebra is a quotient of the free algebra, defined by a binomial ideal admitting a Grobner basis which can be encoded as a regular set; we call such a Grobner basis regular. We give several examples of bi-automaton algebras, and show how automata con

Beräkning av brandmotståndet för avskiljande konstruktioner med luftspalt

I allt fler länder börjar en brandteknisk klassificering av byggnadsdelar tillåtas som bygger på en analytisk behandlning i stället för på resultat av ugnprovningar enligt ISO834. I Sverige godtas sedan lång tid en analytisk brandteknisk dimensionering av bärande och avskiljande konstruktioner som ett alternativ till standardiserad termisk påverkan enligt ISO 834. En väsentlig förutsättning för en

Blood lead concentration after a shotgun accident.

In an accidental shooting, a man in his late forties was hit in his left shoulder region by about 60 lead pellets from a shotgun. He had injuries to the vessels, the clavicle, muscles, and nerves, with total paralysis of the left arm due to axonal injury. After several surgical revisions and temporary cover with split skin, reconstructive surgery was carried out 54 days after the accident. The bra