Genome-wide regulatory deterioration impedes adaptive responses to stress in inbred populations of Drosophila melanogaster : inbreeding under stress assessed by RNAseq
Inbreeding depression is often intensified under environmental stress (i.e., inbreeding–stress interaction). Although the fitnessconsequences of this phenomenon are well-described, underlying mechanisms such as an increased expression of deleterious allelesunder stress, or a lower capacity for adaptive responses to stress with inbreeding, have rarely been investigated. We investigated afitness compon