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Background Laser capture microdissection (LCM) can be applied to tissues where cells of interest are distinguishable from surrounding cell populations. Here, we have optimized LCM for fresh frozen normal breast tissue where large amounts of fat can cause problems during microdissection. Since the amount of DNA needed for genome wide analyses, such as single nucleotide polymorphism (SNP) arrays, is

Critical infrastructures provide essential services for the functioning of the society, and disruption of these services can lead to large-scale consequences. Hence, it is of utmost importance to analyze the vulnerability of critical infrastructures and use the results to guide decisions of improving their robustness towards strains. Since real-life critical infrastructures can be regarded as comp

The gene for the human glandular kallikrein, prostate-specific antigen, has been cloned. The sequence of 7130 nucleotides encompassing the gene and 633 bp of 5' and 639 bp of 3' flanking DNA has been determined. The translation initiation site was slightly heterogeneous, yielding 5' non-translated leader sequences of 41 and 35 bp. The gene is divided into five exons, with introns located at positi

A general theory for plastic loading at corners is presented that includes Koiter's theory as a special case. This theory is derived within a thermodynamic framework and includes non-associated as well as associated theory. The non-associated theory even allows the number of potential functions to differ from the number of yield functions. The properties of the matrix of plastic moduli as well as

n this paper a constrained system of linear equations is considered. These equations do, for instance, appear as a result of finite element formulations of static equilibrium problem for solids. Two classical methods for the solution of the equations are discussed; the method using elimination of constrained coordinates and a method using Lagrangian multipliers. The relation to the minimization of

En delrapport från forskningsprojektet "Omstrukturering av sjukvårdsutbudet inom ett sjukvårdsområde"

From a combination of radiative lifetime measurements, performed with a time-resolved laser-induced fluorescence technique, for nine odd-parity levels of Ir I and four odd-parity levels of Ir II and branching fraction calculations, extended sets of transition probabilities have been derived for transitions of astrophysical interest. The new results are compared with the few experimental data avail

We study the extension of what class of linear time invariantplants may be transformed into SPR systems introducingan observer. It is shown that for the open loopstable systems a cascaded observer achieves the result.For the open loop unstable systems an observer-basedfeedback is required to success. In general any system stabilizableand observable may be transformed into an SPRsystem. This overco

Streptococcus pyogenes (group A streptococci, GAS) is a potent human pathogen known to express a number of cell surface associated virulence factors. It is an established fact that these different surface proteins play an important role during infection. Thus, M family proteins interact with host immune system components allowing streptococci to evade phagocytosis. Another important group of bacte

Usually the mel-frequency cepstral coefficients (MFCCs) are derived via Hamming windowed DFT spectrum. In this paper, we advocate to use a so-called multitaper method instead. Multitaper methods form a spectrum estimate using multiple window functions and frequency-domain averaging. Multitapers provide a robust spectrum estimate but have not received much attention in speech processing. Our speake

A new method using Hamming codes to construct base matrices of (J, K)-regular LDPC convolutional codes with large free distance is presented. By proper labeling the corresponding base matrices and tailbiting these parent convolutional codes to given lengths, a large set of quasi-cyclic (QC) (J, K)-regular LDPC block codes with large minimum distance is obtained. The corresponding Tanner graphs hav

Popular Abstract in English Microorganisms can be used for production of pharmaceutical substances. With the introduction of gene technology, it is possible to transfer information from one organism to the other, thereby making the receiving organism capable of producing substances that it did not so before. This development is very important for e.g. production of therapeutic proteins However, whMicroorganisms can be used for production of pharmaceutical substances. With the introduction of gene technology, it is possible to transfer information from one organism to the other, thereby making the receiving organism capable of producing substances that it did not so before. This development is very important for e.g. production of therapeutic proteins However, when using living organisms fo