Nowadays, superparamagnetic iron oxide nanoparticles (SPIONs) have a dominant role in many subfields of biomedicine. Owing to their peculiar properties, they can be employed for magnetic separation, drug delivery, diagnostics, and hyperthermia treatments. However, these magnetic nanoparticles (NPs) suffer from low unit magnetization due to size constraints (up to 20-30 nm) to exhibit superparamagn

Leishmaniasis is considered one of the most untreated tropical diseases in the world. In this study, we investigated the in vitro leishmanicidal activity and cytotoxicity of various isolated lichen substances, including atranorin (1), usnic acid (2), gyrophoric acid (3), salazinic acid (4), galbinic acid (5), and parietin (6), and some semi-synthetic imine derivatives of usnic acid (7, 8, 9) and a

Background: Mild traumatic brain injury (mTBI) is a common cause for seeking care. Previous studies have shown considerable variations in TBI management. New guidelines may have influenced management routines. Methods: This is a descriptive cross-sectional study, collecting data through structured questionnaires. All Swedish emergency hospitals that manage and treat adult patients with mTBI (React

Purpose: To illustrate the technique of antegrade in situ laser fenestration (ISLF) on a predesign custom-manufactured stent-graft with single reinforced fenestration for use in emergency endovascular repair of complex abdominal aortic aneurysms (AAAs). Technique: A short custom-made device (CMD) fenestrated graft was predesigned with a single preloaded 8 mm strut-free fenestration at 12 o’clock p

Glacio-hydrological modeling is a key task for assessing the influence of snow and glaciers on water resources, essential for water resources management. The present study aims to enhance a conceptual hydrological model (namely Glacial Snow Melt (GSM)) by data-driven and swarm computing for enhancing the accuracy of rainfall runoff prediction. The proposed framework combines the conceptual hydrolo

The majority of activated B cells differentiate into IgA plasma cells, with the gut being the largest producer of immunoglobulin in the body. Secretory IgA antibodies have numerous critical functions of which protection against infections and the role for establishing a healthy microbiota appear most important. Expanding our knowledge of the regulation of IgA B-cell responses and how effective muc

Following antigen encounter, two distinct processes modify immunoglobulin genes. The variable region is diversified by somatic hypermutation while the constant region may be changed by class-switch recombination. Although both genetic events can occur concurrently within germinal centre B cells, there are examples of each occurring independently of the other. Here we compare the contributions of c

Self-assembly gold nanostructured membranes are created to mechanically stabilize the catalyst movement during metal assisted chemical etching. This results in an improved vertical control of the etching profile for high aspect ratio silicon microstructures. The new method is a robust and cheap microfabrication for dense micro-patterns on a large area, such as diffraction gratings for hard X-ray p

SAP is required for proper T cell help in germinal centers (GCs). Biram et al. show that SAP-independent GCs are formed within Peyer's patches. These GCs host highly diversified clones that are subjected to mild selection forces, demonstrating that clonal diversification can be uncoupled from clonal selection in chronic GCs.

We conducted a multi-ancestry genome-wide association study of prostate-specific antigen (PSA) levels in 296,754 men (211,342 European ancestry; 58,236 African ancestry; 23,546 Hispanic/Latino; 3,630 Asian ancestry; 96.5% of participants were from the Million Veteran Program). We identified 318 independent genome-wide significant (p≤5e-8) variants, 184 of which were novel. Most demonstrated eviden

Existing studies demonstrate that although peace and conflict studies (PCS) emerged from a deep connection between political activism and research, the field has increasingly moved toward promoting liberal ideals of peace that sustain the status quo. Amidst this trend, many scholars have pushed research and education programs to explore beyond a hegemonic liberal peace, for example by diversifying

What should count as legitimate forms of reasoning in public deliberation is a contested issue. Democratic theorists have argued that storytelling may offer a more accessible form of deliberation for marginalised citizens than ‘rational argumentation’. We investigate the empirical support for this claim by examining Swedish citizens’ use of storytelling in written communication with the political

Uppsatsen undersöker religiösa aktörers sociala insatser under mottagningskrisen i Sverige 2015 och 2016. Under mottagningen av 160 000 personer på flykt behövde myndigheterna ta stöd i civilsamhällesorganisationer, varav många religiösa aktörer engagerade sig i mottagningsarbete på olika sätt. Uppsatsen syftar till att skapa förståelse för hur och varför religiösa aktörer bedriver sociala insatseThe essay examines the social work of religious actors during the reception crisis in Sweden in 2015 and 2016. During the reception of 160,000 refugees, the authorities needed support from civil society organizations, many of which involved religious actors in the reception work in various ways. The essay aims to create an understanding of how and why religious actors carry out social work in the

Accurately categorizing home furnishing items into interior design style groups plays a crucial role in delivering personalized recommendations that align with customers' design style preferences. However, manually labeling items by experts is a costly and resource-intensive task. To address this challenge, deep learning methods are used to automate the manual labeling of IKEA home furnishing