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An examination of the effect of different methods of scoring pain after a total knee replacement on the number of patients who report unchanged or worse pain.

We identified a group of patients from the Swedish Arthroplasty Register who reported no relief of pain or worse pain one year after a total knee replacement (TKR). A total of two different patient-reported pain scores were used during this process. We then evaluated how the instruments used to measure pain affected the number of patients who reported no relief of pain or worse pain, and the relat

Factors affecting recall rate and false positive fraction in breast cancer screening with breast tomosynthesis - A statistical approach.

In this study, we investigate which factors affect the false positive fraction (FPF) for digital breast tomosynthesis (DBT) compared to digital mammography (DM) in a screening population by using classification and regression trees (C&RT) and binary marginal generalized linear models. The data was obtained from the Malmö Breast Tomosynthesis Screening Trial, which aimed to compare the performa

Doomed to be Entrepreneurial: Institutional Transformation or Institutional Lock-Ins of 'New' Universities?

Universities worldwide are facing enormous strains as a result of increased external expectations where global visibility should be mixed with local and regional utility. In debates on the future of higher education, becoming an entrepreneurial university has been highlighted as a novel - although perhaps a more hybrid - way to deal with this challenge. However, while the label entrepreneurial poi

Accuracy of four-dimensional phase-contrast velocity mapping for blood flow visualizations: a phantom study.

BackgroundTime-resolved three-dimensional, three-directional phase-contrast magnetic resonance velocity mapping (4D PC-MRI) is a powerful technique to depict dynamic blood flow patterns in the human body. However, the impact of phase background effects on flow visualizations has not been thoroughly studied previously, and it has not yet been experimentally demonstrated to what degree phase offsets

Fairness is intuitive

In this paper we provide new evidence showing that fair behavior is intuitive to most people. We find a strong association between a short response time and fair behavior in the dictator game. This association is robust to controls that take account of the fact that response time might be affected by the decision-maker’s cognitive ability and swiftness. The experiment was conducted with a large an

Factors governing human fear of brown bear and wolf

This article analyzes people's subjectively experienced fear in areas with presence of brown bear or wolf. Departing from the Human-Environment Interaction Model (Küller, R. 1991) a hypothetical model of environmental and individual antecedents of fear was tested using structural equation modeling of survey data (n = 391). In the model of fear of brown bear, the main predictor was the appraisal of

Self-doubters, strugglers, storytellers, surfers and others: Images of self-identities in organization studies

This article provides an overview of the key images of identity in organizations found in the research literature. Image refers to the overall idea or conceptualization, capturing how researchers relate to - and shape - a phenomenon. Seven images are suggested: self-doubters, strugglers, surfers, storytellers, strategists, stencils and soldiers. These refer to how the individual is metaphorically

Vicariance divergence and gene flow among islet populations of an endemic lizard.

Allopatry and allopatric speciation can arise through two different mechanisms: vicariance or colonization through dispersal. Distinguishing between these different allopatric mechanisms is difficult and one of the major challenges in biogeographical research. Here, we address whether allopatric isolation in an endemic island lizard is the result of vicariance or dispersal. We estimated the amount

Comparing knowledge bases: on the geography and organization of knowledge sourcing in the regional innovation system of Scania, Sweden

This paper deals with knowledge flows and collaboration between firms in the regional innovation system of southern Sweden. The aim is to analyse how the functional and spatial organization of knowledge interdependencies among firms and other actors varies between different types of industries that draw on different types of knowledge bases. We use data from three case studies of firm clusters in

Exposure determinants of phthalates, parabens, bisphenol A and triclosan in Swedish mothers and their children.

Chemicals such as phthalates, parabens, bisphenol A (BPA) and triclosan (TCS), used in a wide variety of consumer products, are suspected endocrine disrupters although their level of toxicity is thought to be low. Combined exposure may occur through ingestion, inhalation and dermal exposure, and their toxic as well as combined effects are poorly understood. The objective of the study was to estima

Why do seals have cones? Behavioural evidence for colour-blindness in harbour seals.

All seals and cetaceans have lost at least one of two ancestral cone classes and should therefore be colour-blind. Nevertheless, earlier studies showed that these marine mammals can discriminate colours and a colour vision mechanism has been proposed which contrasts signals from cones and rods. However, these earlier studies underestimated the brightness discrimination abilities of these animals,

Cerebrospinal Fluid Levels of Heart Fatty Acid Binding Protein are Elevated Prodromally in Alzheimer's Disease and Vascular Dementia

Heart fatty acid binding protein (HFABP) is expressed in the brain and is elevated in cerebrospinal fluid (CSF) from patients with several forms of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease with dementia, Lewy body dementia, vascular dementia (VaD), and Creutzfeldt-Jakob disease. However, whether HFABP in CSF is a stable biomarker or if it can help predict co

Usage Tests of Oak Moss Absolutes Containing High and Low Levels of Atranol and Chloroatranol.

Atranol and chloroatranol are strong contact allergens in oak moss absolute, a lichen extract used in perfumery. Fifteen subjects with contact allergy to oak moss absolute underwent a repeated open application test (ROAT) using solutions of an untreated oak moss absolute (sample A) and an oak moss absolute with reduced content of atranol and chloroatranol (sample B). All subjects were in addition

Fibroblast growth factor 21 prevents glycemic deterioration in insulin deficient mouse models of diabetes.

In type 1 diabetes, there is a rapid loss of glycemic control immediately after onset of the disease. We aimed to determine if the deterioration of glycemic control that occurs early after the onset of insulin-deficient diabetes could be blunted by treatment with recombinant fibroblast growth factor 21 (FGF21). Normal C57BL/6J mice made diabetic by a single high dose injection of streptozotocin (S

Decomposing color structure into multiplet bases

We illustrate how QCD color structure elegantly can be decomposed into orthogonal multiplet bases corresponding to irreducible representations of SU(N-c) with the aid of Wigner 3j and 6j coefficients. We also show how to calculate the relevant 3j and 6j coefficients using multiplet bases and birdtrack techniques and argue that only a relatively small number of Wigner 3j and 6j coefficients are req

Transient studies on InAs/HfO2 nanowire capacitors

Single-shot transients and deep-level transient spectroscopy are used to investigate the origins of capacitance hysteresis in n-doped InAs nanowire/HfO2 capacitors. Capacitance transients with a characteristic time in the order of 100 mu s are attributed to emission from electron traps, located in the oxide film. The trap energy is determined to be in the range from 0.12 to 0.17 eV with capture cr

HIF-2α Expression Is Suppressed in SCLC Cells, Which Survive in Moderate and Severe Hypoxia When HIF-1α Is Repressed.

Small cell lung carcinoma (SCLC) is extremely aggressive and frequently metastasizes widely in its early stage. Because tumor hypoxia is related to aggressive tumor behavior and the hypoxic adaptation of SCLC is poorly documented, we stained SCLC tumors arranged in a tissue microarray for hypoxia-inducible factor (HIF)-1α and HIF-2α proteins. We found an overall lack of HIF-2α protein expression,

Apolipoprotein B100 autoimmunity and atherosclerosis - disease mechanisms and therapeutic potential.

PURPOSE OF REVIEW: Adaptive immune responses have been shown to play an important role in the atherosclerotic disease process and both pathogenic and protective immunity has been identified. Apolipoprotein (apo) B100 appears to be a key antigen and novel therapies modulating immune responses against apo B100 have shown promising results in experimental models. This review will discuss recent deve