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Experiences of activity monitoring and perceptions of digital support among working individuals with hip and knee osteoarthritis – a focus group study

Background: Mobile health (mHealth), wearable activity trackers (WATs) and other digital solutions could support physical activity (PA) in individuals with hip and knee osteoarthritis (OA), but little is described regarding experiences and perceptions of digital support and the use of WAT to self-monitor PA. Thus, the aim of this study was to explore the experiences of using a WAT to monitor PA an

A novel Bayesian approach for disentangling solar and geomagnetic field influences on the radionuclide production rates

Cosmogenic radionuclide records (e.g., 10Be and 14C) contain information on past geomagnetic dipole moment and solar activity changes. Disentangling these signals is challenging, but can be achieved by using independent reconstructions of the geomagnetic dipole moment. Consequently, solar activity reconstructions are directly influenced by the dipole moment uncertainties. Alternatively, the known

Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice

Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isoforms, and due to the limited channel surface areas that permit inhibitor binding. The few AQP9 inhibitor molecules described to date were not suitable

Semiconductor-ferromagnet-superconductor planar heterostructures for 1D topological superconductivity

Hybrid structures of semiconducting (SM) nanowires, epitaxially grown superconductors (SC), and ferromagnetic-insulator (FI) layers have been explored experimentally and theoretically as alternative platforms for topological superconductivity at zero magnetic field. Here, we analyze a tripartite SM/FI/SC heterostructure but realized in a planar stacking geometry, where the thin FI layer acts as a

Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading

In Alzheimer’s disease (AD), younger symptom onset is associated with accelerated disease progression and tau spreading, yet the mechanisms underlying faster disease manifestation are unknown. To address this, we combined resting-state fMRI and longitudinal tau-PET in two independent samples of controls and biomarker-confirmed AD patients (ADNI/BioFINDER, n = 240/57). Consistent across both sample

Bias correction of GPM IMERG Early Run daily precipitation product using near real-time CPC global measurements

This study focused on improving the performance of the near real-time Integrated Multi-satellitE Retrievals for Global Precipitation Measurement (IMERG) Early Run (IMERG-E) product based on a newly developed bias-correction scheme, LSCDF. The LSCDF was established by integrating the mean-based Linear Scaling (LS) and quantile-mapping Cumulative Distribution Function (CDF) matching approaches. The

A case survey of offshoring–backshoring cases : The influence of contingency factors

This study aims at investigating the influence of contingency factors on the drivers of offshoring and backshoring decision processes. A case survey of existing case studies on backshoring was performed with qualitative comparative analysis (QCA). In total, 43 cases from 16 research papers were analyzed. The results showed that many factors act as contingencies for the backshoring decision, namely

The 2030 Agenda for Sustainable Development : Transformative Change through the Sustainable Development Goals?

The 2030 Agenda of the United Nations comprises 17 Sustainable Development Goals (SDGs) and 169 sub-targets which serve as a global reference point for the transition to sustainability. The agenda acknowledges that different issues such as poverty, hunger, health, education, gender equality, environmental degradation, among others, are intertwined and can therefore only be addressed together. Impl

High diversity of arthropod colour vision : from genes to ecology

Colour vision allows animals to use the information contained in the spectrum of light to control important behavioural decisions such as selection of habitats, food or mates. Among arthropods, the largest animal phylum, we find completely colour-blind species as well as species with up to 40 different opsin genes or more than 10 spectral types of photoreceptors, we find a large diversity of optic

Colour vision in thrips (Thysanoptera)

Insects are an astonishingly successful and diverse group, occupying the gamut of habitats and lifestyle niches. They represent the vast majority of described species and total terrestrial animal biomass on the planet. Their success is in part owed to their sophisticated visual systems, including colour vision, which drive a variety of complex behaviours. However, the majority of research on insec

Colour vision in nocturnal insects

The ability to see colour at night is known only from a handful of animals. First discovered in the elephant hawk moth Deilephila elpenor, nocturnal colour vision is now known from two other species of hawk moths, a single species of carpenter bee, a nocturnal gecko and two species of anurans. The reason for this rarity - particularly in vertebrates - is the immense challenge of achieving a suffic

The Effects of Transnational Municipal Networks on Urban Climate Politics in the Global South

Transnational municipal networks (TMNs) have emerged as important actors in the global response to climate change. Environmentalists both within and outside governments have placed great expectations and hopes on these networks. Through their novel form of agency, TMNs are expected to provide cities with a form of ‘extra-legem’ empowerment in their responses to climate change. This empowerment is

Global Political Economy and Development

This chapter introduces four different approaches that have tackled this issue: Environmental Economics, International Political Economy and Development Studies, Global Environmental Governance and Earth System Governance, as well as Political Ecology. It also introduces these perspectives and highlights their maincontributions to the literature in their historical context. The chapter discusses d

Mechanisms of spectral orientation in a diurnal dung beetle

Ball rolling dung beetles use a wide range of cues to steer themselves along a fixed bearing, including the spectral gradient of scattered skylight that spans the sky. Here, we define the spectral sensitivity of the diurnal dung beetle Kheper lamarcki and use the information to explore the orientation performance under a range of spectral light combinations. We find that, when presented with spect

Conclusion : Towards a ‘Deep Debate’ on the Anthropocene

In this edited volume, we explored the contributions that political science as a discipline can offer to the evolving Anthropocene debate. The term Anthropocene denotes a new geological epoch in the Earth’s history in which humans have become the main drivers of planetary-wide changes. Some authors interpret this as good news, pointing to progress as a result of human ingenuity and the endless pos

Colour vision in ants (Formicidae, Hymenoptera)

Ants are ecologically one of the most important groups of insects and exhibit impressive capabilities for visual learning and orientation. Studies on numerous ant species demonstrate that ants can learn to discriminate between different colours irrespective of light intensity and modify their behaviour accordingly. However, the findings across species are variable and inconsistent, suggesting that

The anthropocene debate and political science

Anthropocene has become an environmental buzzword. It denotes a new geological epoch that is human-dominated. As mounting scientific evidence reveals, humankind has fundamentally altered atmospheric, geological, hydrological, biospheric, and other Earth system processes to an extent that the risk of an irreversible system change emerges. Human societies must therefore change direction and navigate

Introduction : A Political Science Perspective on the Anthropocene

Over the past decades, it has become more and more obvious that ongoing globalisation processes have substantial impacts on the natural environment. Studies reveal that intensified global economic relations have caused or accelerated dramatic changes in the Earth system, defined as the sum of our planet’s interacting physical, chemical, biological and human processes (Schellnhuber et al. 2004). Cl

Molecular advances to study the function, evolution and spectral tuning of arthropod visual opsins

Visual opsins of vertebrates and invertebrates diversified independently and converged to detect ultraviolet to long wavelengths (LW) of green or red light. In both groups, colour vision largely derives from opsin number, expression patterns and changes in amino acids interacting with the chromophore. Functional insights regarding invertebrate opsin evolution have lagged behind those for vertebrat

Colour vision in stomatopod crustaceans

The stomatopod crustaceans, or mantis shrimps, are colourful marine invertebrate predators. Their unusual compound eyes have dorsal and ventral regions resembling typical crustacean apposition designs separated by a unique region called the midband that consists of from two to six parallel rows of ommatidia. In species with six-row midbands, the dorsal four rows are themselves uniquely specialized