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Chalk Laboratory I : SMASH ensemble: Ramon Lazkano

I became acquainted with the music of Ramon Lazkano in 2001 through his guitar pieces. I was immediately fascinated with his ideas and his sound palette; somehow, I associated his music to a range of color between white and gray. His is a musical language where harmonics work as shadows and offer glimpses of a music that lives within a very personal and unique instrumental treatment.Later, togethe

MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1

De novo lipogenesis, a hallmark for cancers is required for cellular transformation. Further it is believed that resistance to apoptosis and epithelial-to-mesenchymal-transition(EMT) facilitates metastasis via over-expression of anti-apoptotic Bcl-2. Previously we demonstrated that hsa-miR-195 targets BCL2, induces apoptosis and augmented the effect of etoposide in breast cancer cells. However, th

A sprinkling of gold dust : Pine pollen as a carbon source in Baltic Sea coastal food webs

Allochthonous subsidies to marine ecosystems have mainly focused on biogeochemical cycles, but there has also been recent interest in how terrestrial carbon (C) influences marine food webs. In the Baltic Sea, pine (Pinus sylvestris) pollen is found in large amounts in shallow bays in early summer. Pollen is a significant C-source in freshwater ecosystems and may also be important in coastal food w

Chlorophenol stress affects aromatic amino acid biosynthesis-a genome-wide study

Chlorophenols are a class of chemicals commonly used in preservatives, disinfectants, algaecides, herbicides and pesticides. However, there is a growing evidence that these compounds are a threat to human health. This is alarming as many chlorophenols are common pollutants found in the global environment at potentially biohazardous levels. Despite chlorophenols being abundant, widely used and pois

The changing face of AU Mic b: Stellar spots, spin-orbit commensurability, and transit timing variations as seen by CHEOPS and TESS

AU Mic is a young planetary system with a resolved debris disc showing signs of planet formation and two transiting warm Neptunes near mean-motion resonances. Here we analyse three transits of AU Mic b observed with the CHaracterising ExOPlanet Satellite (CHEOPS), supplemented with sector 1 and 27 Transiting Exoplanet Survey Satellite (TESS) photometry, and the All-Sky Automated Survey from the gr

Adolescents’ Use of Pornography : Trends over a Ten-year Period in Sweden

Using survey data from three nationally representative surveys in 2004, 2009, and 2014 among senior high school students in Sweden, this study investigates trends in adolescents’ lifetime prevalence of pornography use, frequency of pornography use, and type of pornography used over time. While almost all boys and a considerable proportion of girls used pornography across the three waves, the lifet

CO2 emission impacts of introducing heavier and longer trucks in the Swedish transport system

In recent years the possibility to increase maximum length and weight of heavy goods vehicles to allow for High Capacity Vehicles (HCVs) has been debated in Sweden. Proposals to increase maximum weight to 74 tonnes, and length to 34m have caused controversy. Key arguments among proponents are that HCVs will bring about benefits, such as: increasing energy efficiency and decreasing CO 2 emissions,

Production of muons from heavy-flavour hadron decays in pp collisions at √s = 5.02 TeV

Production cross sections of muons from semi-leptonic decays of charm and beauty hadrons were measured at forward rapidity (2.5 < y < 4) in proton-proton (pp) collisions at a centre-of-mass energy s = 5.02 TeV with the ALICE detector at the CERN LHC. The results were obtained in an extended transverse momentum interval, 2 < pT< 20 GeV/c, and with an improved precision compared to previous measurem

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment

How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated with a worse prognosis independently of known clinicopathological features. Furth

Boosting Prosocial Career Aspirations : Loving-Kindness Meditation Relates to Higher Communal Career Goals in Youth

Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increase interest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage. Research has yet to find ways to increase communal career goals. In this study, we test the novel Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increaseinterest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage.Research has yet to find ways to increase communal career goals. In this study, we test the novel hy

Indigestible fraction of guava fruit : Phenolic profile, colonic fermentation and effect on HT-29 cells

Guava fruit is rich in phenolic compounds (PCs), whose metabolic fate has not been explored. Non-digestible carbohydrates and PCs in whole guava (WG) and seedless guava (SG) were submitted to an in vitro colonic fermentation, followed by evaluation of the anti-proliferative activity of the fermentation extracts in HT-29 cancer cell lines. The main PCs in both samples were (+)-gallocatechin and gal