The cannabinoid 1 receptor (CB1R) has a well-established role in appetite regulation. Central CB1R antagonists, notably rimonabant, induced weight loss and improved the metabolic profile in obese individuals, but were discontinued due to psychiatric side-effects. The CB1R is also expressed peripherally, where its effects include promotion of liver fat accumulation, which consumes ATP. Type 2 diabe

I Skåne kan klimatförändringarna förbättra förutsättningarna för produktion av grödor och annan biomassa via förlängd växtsäsong och ökad tillväxt. Samtidigt ökar dock risker för skador, sjukdomar och insektsangrepp. En intensifiering av jordbruk för att ta vara på ökad produktionspotential och för att möta ett ökat behov av biomassa riskerar att förvärra problem som redan finns när det gäller fö

One major problem for integrating study results into a common body of knowledge is the heterogeneity of reporting styles: (1) It is difficult to locate relevant information and (2) important information is often missing. Reporting guidelines are expected to support a systematic, standardized presentation of empirical research, thus improving reporting in order to support readers in (1) finding the

Popular Abstract in Swedish Avhandlingens syfte är att analysera den akademiska debatten kring positiv särbehandling i USA med speciell tonvikt på de svarta amerikanernas historiska och aktuella förhållanden.Affirmative action is a contested policy in both political and academic debates in the United States. It is a policy that has been in place for over three decades and it is now seen as well entrenched in various settings of society, especially in educational and professional areas. However, in recent years affirmative action has been the target for more negative reactions, and many people are expe

Because of deflections under load, contacts on tooth flanks can occur outside the theoretical plane of action between non-conjugated profiles especially when tooth modifications are not appropriate. The main objective of the present paper is to introduce an original model of the dynamic behavior of spur gears when submitted to these particular meshing conditions. The pinion and the gear of the pai

Large-scale star formation in disk galaxies is hypothesized to be driven by global gravitational instability. The observed gas surface density is commonly used to compute the strength of gravitational instability, but according to this criterion, star formation often appears to occur in gravitationally stable regions. One possible reason is that the stellar contribution to the instability has been

Using longitudinal data, this paper investigates the penalty for excess weight in the Swedish labor market, distinguishing between the productivity and the discrimination hypotheses. We analyze employment, income, and sickness absence , using the latter as a direct measure of productivity. We find that excess weight women, but not men, experience a significant employment penalty. Both genders expe

In order to adapt to new conditions that increasing air traffic volumes bring forward, the Swedish Air Navigation Services (ANS) is going through a process of change. In order to meet the new conditions it will be necessary to be more efficient in the work of handling the air traffic. New conditions bring forward new demands, not only on technology and methods used, but also on organizational stru