BackgroundThe goal of the Fifth Annual Baylor College of Medicine & DNAnexus Structural Variation Hackathon was to push forward the research on structural variants (SVs) by rapidly developing and deploying open-source software. The event took place in-person and virtually in August 2023, when 49 scientists from 14 countries and 8 U.S. states collaboratively worked on projects to address critic

Despite a strong emphasis that individual support services should be provided according to needs, the Swedish welfare system often use age to organize support. A change in the Social Service Act in 2018 allows municipalities to provide home care for people above a decided age without individual any assessment of needs. Political parties and pensioners’ organizations’ have proposed for the introduc

A generalized approach derived from Bloch's equation of motion of nuclear magnetic moments is presented to model the frequency, magnetic field, spin density, and temperature dependencies in the electromagnetic permeability tensor for materials with magnetic resonances. The resulting tensor model predicts characteristic polarization signatures which can be observed, for example, in Mueller matrix e

Mary Shelley’s Frankenstein (1818) has been scrutinised in a large variety of fields and from a wide variety of perspectives. Yet, each new published article proves there is more to be uncovered of the novel and its characters. Still, there exists a discrepancy in the attention afforded to its narrators, as the character of Victor Frankenstein is overshadowed by that of the Creature. This phenomen

I den här avhandlingen, syftar jag till att utforska kopplingarna mellan natur, konflikt och fred som bygger på litteratur från freds- och konflikstudier och miljöfredsbyggande. Jag hävdar att miljöfrågor, särskilt relaterade till fördelningen av naturresurser, är centrala för att förstå strukturella förhållanden möjliggör både konflikt och fred. För att svara på förskningsfrågan utforskar jag hurIn this dissertation, I aim to explore the links between nature, conflict, and peace building on literature from peace and conflict studies and environmental peacebuilding. I argue that environmental issues, especially related to the distribution of natural resources, are central to understanding structural conditions allowing for both conflict and peace. In order to answer the research question,

Purpose of ReviewThis review aims to summarize the evolution and recent developments in the classification of ANCA associated vasculitis (AAV) and to summarize evaluations of the 2022 ACR/EULAR classification criteria of AAV in several cohorts.Recent FindingsThe classification of AAV has been a field of controversy for some time. The parallel existence of classification criteria and disease defini

The question of discretion in law is often framed as a technical question of correctly applying the rules to the situation at hand. This article questions that framing of discretion and argues that, in a democracy, the exercise of legal discretion is not a technical, but a political question. It a communicative practice, involving the giving and taking of reasons by persons oriented by communicati

Läsarsvar om den amerikanske generalen Joseph Stilwells verksamt i Kina före och under andra världskriget.

When starting and running a new business, entrepreneurs often face stressors and sleep turbulence such as insomnia that disrupt their daily activities. These challenges frequently result in increased exhaustion, which negatively affects cognitive functioning and entrepreneurial performance. Drawing on existing research, I introduce a conceptual framework to gain valuable understanding into the int

Purpose – This paper aims to extend insights about the relationship between inter-organizational collaboration and approaches to control from the perspective of decision-makers. We investigate the relationship between approaches to control and intended forms of integration between actors responsible for solving the complex problem of integrated person-centered care for elderly with diverse and sig

Thomas Mathiesen has been a source of inspiration for research in critical sociology, criminology, and the sociology of law for many decades. Mathiesen’s impact extends far beyond the academic realm, as his action research lives on. This intervention discusses the ongoing influence of Mathiesen’s action research approach, which integrates research, education, and societal impact. This is illustrat

This study reports on the effects of conformationally controlled amphiphilicity of antimicrobial peptides (AMPs) on their ability to coat TiO2 nanoparticles (NPs) and boost the photocatalytic antimicrobial effects of such NPs. For this, TiO2 NPs were combined with AMP EFK17 (EFKRIVQRIKDFLRNLV), displaying a disordered conformation in aqueous solution but helix formation on interaction with bacteri

This study aims to gain qualitative insights about and compare public responses to COVID-19 crisis management during the different pandemic phases and across three countries—Norway, Sweden and Italy. To do so, we have carried out a qualitative content analysis of a selection of 2606 tweets containing the term ‘face mask’ in Italian, Norwegian, and Swedish published between March 1, 2020 and June 3

Bladder cancer is a heterogenous disease, and molecular subtyping is a promising method to capture this variability. Currently, the immune compartment in relation to subtypes is poorly characterized. Here, we analyzed the immune compartment in bladder tumors and normal bladder urothelium with a focus on T cell subpopulations using flow cytometry and RNA sequencing. The results were investigated in

Climate may regulate dissolved organic carbon (DOC) composition across the peat-water interface, but experimental evidence is scarce. We manipulated the climate in peatland and recipient surface water mesocosms to reflect four different climate warming scenarios. In half of the mesocosms, the water level was managed to avoid drought, after which responses were recorded during two annual cycles. It

Cortical arealization arises during neurodevelopment from the confluence of molecular gradients representing patterned expression of morphogens and transcription factors. However, whether similar gradients are maintained in the adult brain remains unknown. Here, we uncover three axes of topographic variation in gene expression in the adult human brain that specifically capture previously identifie

Introduction: FLASH radiotherapy (RT) has emerged as a promising modality, demonstrating both a normal tissue sparing effect and anticancer efficacy. We have previously reported on the safety and efficacy of single fraction FLASH RT in the treatment of oral tumors in canine cancer patients, showing tumor response but also a risk of radiation-induced severe late adverse effects (osteoradionecrosis)