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Biological tissue consists of populations of cells exhibiting different responses to pharmacological stimuli. To probe the heterogeneity of cell function, we propose a multiplexed approach based on real-time imaging of the secondary messenger levels within each cell of the tissue, followed by extraction of the changes of single-cell fluorescence over time. By utilizing a piecewise baseline correct
Background and purpose — Reported revision rates due to dislocation after hemiarthroplasty span a wide range. Dislocations treated with closed reduction are rarely reported despite the fact that they can be expected to constitute most of the dislocations that occur. We aimed to describe the total dislocation rate on the national level, and to identify risk factors for dislocation. Patients and met
Biomass, as a renewable energy source, is available worldwide, is carbon neutral, and can be converted to various types of products depending on the market and on the specific applications. Among different technologies of biomass utilization, thermochemical conversion of biomass is the most efficient method with the shortest time scale of the process. Thermochemical conversion can be used to produ
Constraining the climate impact of particulate brown carbon (BrC) will require identification of formation mechanisms and isolation of its different components to allow for source apportionment. For fresh combustion aerosols, the light absorption characteristics and the Absorption Ångstrom Exponent (AAE) are principally controlled by the combustion conditions in which the particles formed and evol
The aim of this study is to explore how academic teachers view and experience challenges in teaching communication. During a teacher training course 92 STEM teachers developed, implemented, evaluated and reported on altogether 44 authentic communication elements. Content analysis was used for analysing teachers’ written answers to questions before the course, and reports after the course. The resu
In the late stage of Parkinson's disease (PD), there is an increasing disease burden not only for the patients but also for their informal caregivers and the health and social services systems. The aim of this study was to explore experiences of late-stage PD patients' and their informal caregivers' satisfaction with care and support, in order to better understand how they perceive the treatment a
Background: Occupational therapists are an essential healthcare profession and play a vital role in rehabilitating patients in the activities of daily life. Nevertheless, many occupational therapists in Sweden are leaving the profession and this jeopardises occupational therapy services. Objective: To explore factors that cause occupational therapists to seriously consider leaving their profession
As the literature on entrepreneurship education grows, the issue of equality in entrepreneurship education has been raised; i.e., whether students are educated to become entrepreneurs equally. This article provides a critical and thought-provoking analysis of a portfolio of practices that, on the surface, appear to be successful in training entrepreneurs. To this purpose, we initiate a debate on w
Importance: Preterm birth has been associated with increased risk of heart failure (HF) early in life, but its association with new-onset HF in adulthood appears to be unknown. Objective: To determine whether preterm birth is associated with increased risk of HF from childhood into mid-adulthood in a large population-based cohort. Design, Setting, and Participants: This national cohort study was c
The majority of LGBT research in schools has focused almost exclusively on sexuality diversity, leaving the experiences of transgender and gender diverse youth a much neglected area of scholarly inquiry. Using qualitative in‐depth interviews, we explore the schooling experiences of transgender and non-binary youth in South Africa. Our findings highlight that transgender and non-binary youth face h
Background: Ambulatory blood pressure monitoring (ABPM) is increasingly recommended for clinical use, but more knowledge about the prevalence and variability in ABPM-derived phenotypes in the general population is needed. We describe these parameters in the community-based Swedish CArdioPulmonary bioImage Study (SCAPIS) cohort. Methods: We examined 5881 men and women aged 50–64 with 24-hour ABPM r
Autonomous vehicles allow utilisation of new optimal driving approaches that increase vehicle safety by combining optimal all-wheel braking and steering even at the limit of tyre–road friction. One important case is an avoidance manoeuvre that, in previous research, for example, has been approached by different optimisation formulations. An avoidance manoeuvre is typically composed of an evasive p
Detta dokument är framtaget som en intern rapport inom MerSam – Meritvärde av samverkansskicklighet, vars projekttid löpt under 2017 – 2020. MerSam är ett av Vinnovas 17 finansierade K3-projekt. Rapporten utgör en sammanställning av insamlad information från dokument, dialoger, workshoppar, intervjuer och enkäter. Rapporten visar på användning av begrepp och tolkning av begrepp. Syftet är att besk
Rapport som sammanfattar utvärderingen av den första generationen av tematiska samverkansinitiativ vid Lunds universitet 2017-2019.
Samverkansuppgiften har gradvis fått en tydligare roll sedan mitten av 1990-talet och är idag en nödvändig och central uppgift för högskolor och universitet i Sverige, inte minst för att hantera vår tids samhällsutmaningar. Det finns få tecken på att denna utveckling kommer att vända och det är därför viktigt att vi inom sektorn för en dialog kring hur vi tar oss an och värderar det arbete som ske
This article connects to the discussion on skills and knowledge during the early industrialisation. It focuses on how two out of four technical secondary schools in Sweden (Malmö and Borås) lived up to their aims communicated by politicians and other stakeholders: to provide emerging industries and crafts in their regions with technicians and to prepare for studies at the Technological Institute.
A major function of the kidney is to, by glomerular filtration, maintain the overall steady-state of 5–30 kDa proteins, many of which are signalling molecules. This function of the kidney has been overlooked, since predominantly low-molecular-mass substances <1 kDa have been used to measure or estimate glomerular filtration rate (GFR). The use of cystatin C (13 kDa) as a marker of GFR has allowed
The human-driven loss of biodiversity has numerous ecological, social, and economic impacts at the local and global levels, threatening important ecological functions and jeopardizing human well-being. In this perspective, we present an overview of how tropical defaunation—defined as the disappearance of fauna as a result of anthropogenic drivers such as hunting and habitat alteration in tropical
