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Water is the matrix of life, and its confinement in nanocavities is a central topic from geophysics to nanotribology. Phyllosilicate layered minerals provide natural nanocavities for water due to their capacity to hydrate by confining water molecules in the interlamellar space. However, the hydration of phyllosilicates at the nanoscale is not a fully understood process and depends on the geologica
Ultrasound Optical Tomography (UOT) combines the high-resolution imaging capability of ultrasound with measurements of light absorption and scattering properties of human tissue. This non-invasive technique could distinguish between cancerous and non-cancerous lesions inside the breast tissue, follow tumor shrinkage during preoperative treatment, or provide information on blood oxygenation levels.
Optical imaging utilize light to analyze biological tissues in detail, non-invasively and without harmful radiation. Examples include ultrasound optical tomography and photoacoustic imaging; both use a limited number of wavelengths. Diffuse reflectance spectroscopy, another optical technique, covers a continuous wavelength range, but without generating an image. This study focuses on extended-wave
OBJECTIVE: The availability of tissue-mimicking materials (TMMs) for manufacturing high-quality phantoms is crucial for standardization, evaluating novel quantitative approaches, and clinically translating new imaging modalities, such as photoacoustic imaging (PAI). Recently, a gel comprising the copolymer styrene-ethylene/butylene-styrene (SEBS) in mineral oil has shown significant potential as T
Review of Klas Gustafson's biography of Swedish singer Monica Zetterlund, "Enkel, vacker, öm".
Background: Associations between subjective sleep quality and stage-specific heart rate (HR) may have important clinical relevance when aiming to optimize sleep and overall health. The majority of previously studies have been performed during short periods under laboratory-based conditions. The aim of this study was to investigate the associations of subjective sleep quality with heart rate during
It is not acceptable that a judge because of ‘fear’ hands down a wrongful judgment. This was mentioned already by Isidore of Seville in his Sententiae and is part of the oaths of judges in many jurisdictions, from the 1230s onwards until this day. The ‘fear’ that is relevant could relate to one of the parties but also other persons in power. Thus, it relates not only to impartiality but – above alIt is not acceptable that a judge because of ‘fear’ hands down a wrongful judgment. This was mentioned already by Isidore of Seville in his Sententiae and is part of the oaths of judges in many jurisdictions, from the 1230s onwards until this day. The ‘fear’ that is relevant could relate to one of the parties but also other persons in power. Thus, it relates not only to impartiality but – above al
In this paper, we present two new provable nonce-misuseresistantAEAD modes based on tweakable block ciphers and universalhash functions. These new modes target equipping high-speed applicationswith nonce-misuse-resistant AEAD (MRAE). The first mode, LowLatency Synthetic IV (LLSIV), targets similar performance on single-coreplatforms to SCT-2, while eliminating the bottlenecks that make SCT-2not fu
Regulatory authorities must balance ensuring evidence of efficacy and safety of new drugs. Various regulatory pathways, such as the accelerated approval program in the United States (US), allow authorities to quickly approve drugs for severely ill patients by granting market authorization based on surrogate end points and pending confirmatory trials. In this cross-sectional study, we considered 23
The latest Novo Nordisk revelations provide the strongest argument yet for a Sunshine Act for drug and medical device companies operating in the UK
The relationship between bibliography and book history is discussed in three cases based on the the national bibliography of Denmark: The system of book formats as a system of communication. The bibliographical development of chap books in the eighteenth and nineteenth century, and the bibliographical change in the author function in the eighteenth century.
HuvudbudskapDialektisk beteendeterapi för ungdomar (DBT-A) förebygger återfall i självskadebeteende. Internetförmedlad känsloregleringsterapi (IERITA) kan förebygga nya episoder av icke-suicidalt självskadebeteende.SlutsatserEfter att ha granskat den vetenskapliga litteraturen har SBU dragit följande slutsatser:DBT-A minskar antalet ungdomar med självskadebeteende som får ett återfall. Behandlinge
Protein-ligand complex formation is fundamental to biological function. A central question is whether proteins spontaneously adopt binding-competent conformations to which ligands bind conformational selection (CS) or whether ligands induce the binding-competent conformation induced fit (IF). Here, we resolve the CS and IF binding pathways by characterizing protein conformational dynamics over a w
