PURPOSE: Adjuvant chemotherapy versus observation and chemotherapy at progression was evaluated in 162 patients in a prospective randomized multicenter study. We also evaluated DNA-measurements as an additional prognostic factor.PATIENTS AND METHODS: Patients received adjuvant carboplatin AUC 7 every 28 days for six courses (n = 81) or no adjuvant treatment (n = 81). Eligibility included surgicall

This paper analyses the marriage patterns of multi-ethnic people–who have one native-born and one foreign-born parent–born in Sweden (multi-ethnic Swedes). Based on Swedish register data from the period 1997–2016 and multinomial regression analysis, this paper looks into the generational transmission of inter- and intra-marriage for multi-ethnic Swedes versus mono-ethnic individuals who have two n

Purpose: [18F]flortaucipir binds to paired helical filament tau and accurately identifies tau in Alzheimer’s disease (AD). However, “off-target” binding interferes with the quantification of [18F]flortaucipir in several brain regions. Recently, other tau PET tracers have been developed. Here, we compare [18F]flortaucipir with the novel tau tracer [18F]RO948 head-to-head in vivo. Methods: We includ

Romulus Bucur is a renowned writer and literary critic. He is also faculty member at Transylvania University of Brasov, institution well-known for its courses of creative writing and translation studies. "Glosses" is a nimbly written theoretical book wherein many topics are analyzed. One of the most important is the work of Alexandru Musina, editor, writer, professor, and mentor of the Group of Br

Family history (FH) of cancer is an important factor of increased risk of several cancers. Although the association between FH of cancer and concordant cancer risk has been reported in many previous epidemiological studies, no comprehensive prospective study with adjustment for lifestyle habits has evaluated the association of FH of cancer and concordant cancer risk. We investigated the associatio

Det finns en stark traditionalistisk rörelse inom katolska kyrkan. Bakgrunden är de reformer som genomfördes som ett resultat andra vatikankonciliet 1962-1965. Konciliet banade väg för en mer öppen form av katolicism, som av många konservativt sinnade katoliker uppfattades som ett avsteg från den katolska tron och traditionen. För att värna vad man uppfattar som den sanna katolicismen har dessa tr

A potential drop method, as used for estimations of crack lengths during three‐point‐beind experiments, is studied. The mechanical state is calculated using a finite element method. The deformed body obtained is used for a subsequent calculation of the electrostatic state. Calculations are performed for both two‐ and three‐dimensional models. The material is assumed to be elastic, linearly hardeni

Notions of research quality are contextual in many respects: they vary between fields of research, between review contexts and between policy contexts. Yet, the role of these co-existing notions in research, and in research policy, is poorly understood. In this paper we offer a novel framework to study and understand research quality across three key dimensions. First, we distinguish between quali

Objective: Survival in cervical cancer has improved little over the last decades. We aimed to elucidate primary treatment patterns and survival. Methods: Population-based study of patients included in the Swedish Quality Registry for Gynecologic Cancer diagnosed 2011–2015. Main outcome was 5-year relative survival (RS). Age-standardised RS (AS-RS) was estimated for the total cohort and for the poo

Our aim is to construct efficient preconditioners for high order discontinuous Galerkin (DG) methods. We consider the DG spectral element method with Gauss‐Lobatto‐Legendre nodes (DGSEM‐GL) for the 1D linear advection equation. It has been shown in [4] that DGSEM‐GL has the summation‐by‐parts (SBP) property and an equivalent finite volume (FV) discretization is presented in [3]. Thus we present a

Deconstruction is one of the more (in)famous theories in recent times. In this paper, I argue that the theory of deconstruction, proposed by Derrida in particular, should be read as a systematic and rigorous examination of key philosophical and semiotic notions, such as sign and meaning. The relevance of taking deconstructive critique seriously is explored with the point of departure in Derrida’s

BACKGROUND: To investigate the value of combined treatment with allopurinol and 5-aminosalicylic (5-ASA) based drugs as maintenance treatment for ulcerative colitis (UC).METHODS: 199 patients with UC in remission but with active disease during the preceding 3 years were included. Allopurinol 100 mg twice daily or placebo was added to the 5-ASA based maintenance treatment. Clinical and endoscopic f

Avhandlingen består av tre oberoende kapitel som alla är empiriska studier av forskare och den roll som olika typer av rörlighet spelar för att forma forskarnas vetenskapliga produktion och karriär.Kapitel 1 studerar effekterna av avregleringen av svensk arbetsmigration, 2008, på publiceringsproduktiviteten hos akademiker verksamma i Sverige. Reformen ledde till en kraftig ökning av antalet asiatiThe thesis consists of three independent chapters. The chapters are all empirical studies of scientists and the role that different types of mobility play in shaping researchers' scientific output and careers.Chapter 1, uses the liberalization of Swedish work migration, in 2008, to study the effect of immigration on the publishing productivity of incumbent academics in Sweden. The reform led to a

PURPOSE: To calculate the normal tissue complication probability (NTCP) of late radiation effects on the rectum and bladder from repetitive CT scans during fractionated high-dose-rate brachytherapy (HDRB) and external beam radiotherapy (EBRT) of the uterine cervix and compare the NTCP with the clinical frequency of late effects.METHODS AND MATERIALS: Fourteen patients with cancer of the uterine ce

Efficient, diode-pumped high energy femtosecond laser systems around 1 μm based on Yb-gain media are readily commercially available. However, owing to the gain bandwidth limitations, the pulses generated in such lasers are substantially longer than the ones generated in Ti:Sapphire systems. A simple, energy-scalable pulse self-compression scheme for the pulses around 1 μm thus would be of great in

It is essential to gain knowledge about the causes and extent of migratory connectivity between stationary periods of migrants to further the understanding of processes affecting populations, and to allow efficient implementation of conservation efforts throughout the annual cycle. Avian migrants likely use optimal routes with respect to mode of locomotion, orientation and migration strategy, infl

Climate changes induce warmer climate with stronger and more frequent extreme events. Due to the uncertain nature of climate, accurate simulation of future conditions is impossible and a major challenge is the selection of climate data in the impact assessment. This work compares application of three climate data sets in an energy simulation of the EPFL campus: i) Regional Climate Models (RCM data