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Historical building renovation and PV optimisation towards NetZEB in Sweden

Retrofitting historical buildings towards net zero energy building (NetZEB) in Northern countries is facing some issues confirmed in the literature review of this study. Following a holistic approach proposed by the authors, a 150-year old castle situated in Helsingborg, Sweden, was used to evaluate the potential of historical buildings in the Nordics to be turned into a NetZEB building. Following

Supplier involvement in product development : Challenges and mitigating mechanisms from a supplier perspective

This article explores challenges that suppliers experience when being involved in customers’ product development projects, and how these challenges can be mitigated. It presents a framework of supplier involvement in product development involving four dimensions: People-Process-Tools/Technology-Interaction. The framework consists of 24 challenges and associated mitigating mechanisms. The article c

Exploring new ways of thinking about and developing staff practice : the role of modes of thinking

Purpose: Nobel Prize winner Daniel Kahneman’s work on modes of “thinking” provides a comprehensive text which is little explored in respect of work with people who have an intellectual or developmental disability. This paper aims to explore the potential of this work to change staff development and practice. Design/methodology/approach: Key themes from Thinking Fast, and Slow (Kahneman, 2011) are

Transformations : ‘Religious’ radicalism

This chapter provides an overview of some historical struggles against domination that are based in ‘radical religious’ communities. Yet what qualifies as ‘religious’ and ‘radical’ is very open to interpretation, and typical interpretations of ‘religion’ in particular often betray a colonial mindset which this chapter seeks to problematise. By presenting a deliberately broad range of examples and

Artificial gametes and the ethics of unwitting parenthood

In this paper, we explore the ethical and legal implications of a hypothetical use of artificial gametes (AGs): that of taking a person’s cells, converting them to artificial gametes and using them in reproduction – without that person’s knowledge or consent. We note the common reliance on genetic understandings of parenthood in the law, and suggest that injustices may arise if unwitting genetic p

Analysis of pluvial flood damage costs in residential buildings : A case study in Malmö

Pluvial flood damage to residential buildings causes a significant part of direct tangible flood losses. In this study, we investigate the non-hazard variables and sewer system types in relation to damage costs in the city of Malmö, Sweden. A comprehensive data set of around 1000 records of direct damage to residential buildings from a cloudburst event on 31 August 2014 in Malmö, Sweden has been a

Acute sore throat and Fusobacterium necrophorum in primary healthcare : A systematic review and meta-analysis

Purpose The main objective of this review was to describe and quantify the association between Fusobacterium necrophorum (FN) and acute sore throat in primary healthcare (PHC). Methods In this systematic review and meta-analysis, we searched Scopus and PubMed for case-control studies reporting the prevalence of FN in patients attending primary care for an uncomplicated acute sore throat as well as

Comment on “Individual heterozygosity predicts translocation success in threatened desert tortoises”

Scott et al. (Reports, 27 November 2020, p. 1086) bring much-needed attention to species conservation by demonstrating heterozygote superiority among translocated tortoises. However, we believe that their recommended heterozygosity decision rule risks taking conservation genomics backward. We argue that their advice could misguide conservation management aimed at establishing viable populations, a

Policing Vagrancy in Authoritarian Seoul

South Korea’s past offers an example of an authoritarian context in which police roles proliferated. Besides maintaining order, police officers in Seoul were deployed for all sorts of purposes. Police were positioned as representatives of a state that had, in the 1960s and 1970s, ambitious plans for remaking society. Seoul’s large underclass posed, in the visions of City Hall and the central gover

Rule by Association : Japan in the Global Trans-Imperial Culture, 1868-1912

This dissertation argues that during the latter half of the long nineteenth century, colonial powers around the world co-produced a “global trans-imperial culture” that was facilitated by a common knowledge infrastructure, including international congresses, trans-imperial scholarly exchange and expositions. Japan was an important member of this “colonial club” and was deeply engaged with evolving

Nanotechnology as a therapeutic strategy to prevent neuropsychomotor alterations associated with hypercholesterolemia

Hypercholesterolemia has been linked to neurodegenerative disease development. Previously others and we demonstrated that high levels of plasma cholesterol-induced memory impairments and depressive-like behavior in mice. More recently, some evidence reported that a hypercholesterolemic diet led to motor alterations in rodents. Peripheral inflammation, blood-brain barrier (BBB) dysfunction, and neu

Sintering Mechanism of Core@Shell Metal@Metal Oxide Nanoparticles

Metal oxide shell layers are promising candidates to improve the performance of metal nanoparticles (NPs) in various applications. However, despite a significant amount of experimental work on metal@metal oxide (M@MO) NPs, computational modeling is scarce, particularly on the sintering mechanism, which plays a crucial role in both the synthesis and performance of NPs. Here, we present atomic diffu

Regulation of the Muscarinic M3 Receptor by Myocardin-Related Transcription Factors

Myocardin-related transcription factors (MRTFs: myocardin/MYOCD, MRTF-A/MRTFA, and MRTF-B/MRTFB) are co-factors of serum response factor (SRF) that activate the smooth muscle cell (SMC) gene program and that play roles in cardiovascular development and mechanobiology. Gain and loss of function experiments have defined the SMC gene program under control of MRTFs, yet full understanding of their imp

Severity of idiopathic scoliosis is associated with differential methylation : An epigenome‐wide association study of monozygotic twins with idiopathic scoliosis

Epigenetic mechanisms may contribute to idiopathic scoliosis (IS). We identified 8 monozygotic twin pairs with IS, 6 discordant (Cobb angle difference >10°) and 2 concordant (Cobb angle difference ≤2°). Genome‐wide methylation in blood was measured with the Infinium HumanMethylation EPIC Beadchip. We tested for differences in methylation and methylation variability between discordant twins and tes

Visions and Resistance : The Establishment of a New School in a Marketized Educational Landscape

During the last few decades, education globally has been marked by being closely related to the economy. It always was, but today’s commodification and marketization reach into any aspect of the educational system (Ball, 2012; Bartlett et al., 2002). Sweden is a specific case at hand, since privatization and competition between schools have taken especially sinister forms, and have far-reaching ef

Pollination som ekosystemtjänst.

Pollinatörer är en fråga i tiden. I slutet av 1990-talet introducerade Gretchen Daily och Robert Costanza begreppet ekosystemtjänster för att beskriva människans beroende av naturliga processer och produkter som skapas av våra ekosystem. Begreppet har sedan dess fått ett enormt genomslag inom vetenskap och policy och var centralt för IPBES globala utvärdering av biologisk mångfald och ekosystemtjä

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Introduction: Diabetes, as a chronic disease, is the third leading cause of death in developing countries. Hyperglycemia and oxidative stress have been recognized as the main factors involved in pathogenesis of diabetes. On the other hand, the antioxidant system is the first defense mechanism of body against oxidative stress. Falcaria Vulgaris possesses hypoglycemic and antioxidant effects. This s