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Stora skillnader i överdödlighet våren 2020 utifrån födelseland

The Swedish strategy for dealing with covid-19 has been criticized for not accounting for difficulties of conducting voluntary social distancing in settings with household overcrowding, dependence on public transport and large proportion of service sector workers. In such neighbourhoods there is typically a larger proportion of immigrants. We compared all-cause-mortality data in Sweden by country

Clean Production of Levulinic Acid from Fructose and Glucose in Salt Water by Heterogeneous Catalytic Dehydration

Levulinic acid (LA) is considered to be one of the promising organic bio-platform chemicals and intermediates for the synthesis of fuels, chemicals, and polymers. In the present study, heterogeneous catalytic dehydration of hexose sugars, fructose and glucose, using a strong cation exchange resin (hydrogen form) as an acid catalyst, was performed to produce LA in an aqueous medium. The effect of s

Time-resolved dynamics of thiophene dication - Probing parent molecule survival times and multi-step dissociation processes of cyclic molecules by free-electron-laser experiments combined with theoretical simulations

Thiophene is a cyclic molecule that becomes unstable as a molecular dication. We followed the multi-step dissociation dynamics triggered by soft x-ray FEL pulses from SACLA, core-ionizing the S 2p orbital and creating parent dications by the Auger decay. The time-evolution was probed by optical laser pulsesthat reveal the survival lifetime of the parent dication and the build-up of fragmentation p

Use of cardiovascular drugs and risk of incident heart failure in patients with atrial fibrillation

Congestive heart failure (CHF) is the most important cause of death in patients with atrial fibrillation (AF). We aimed to study the association between cardiovascular drugs in AF patients and incident CHF. The study population included all adults (n = 120 756) aged ≥45 years diagnosed with AF in Sweden diagnosed for the period 1998-2006. Outcome was incident congestive heart failure (follow-up 20

Effects of feed composition, protein denaturation and storage of milk serum protein/lactose powders on rehydration properties

Whey powder rehydration is expected to be closely linked to both denaturation and lactosylation of the proteins. This study investigated the relation between the forced imbibition rate of spray-dried milk serum protein/lactose powders and the particle morphology and how it is related to the insoluble and lactosylated protein fraction, respectively. Despite extensive variation in protein denaturati

Family members' lived experiences when a loved one undergoes an interhospital intensive care unit-to-unit transfer : A phenomenological hermeneutical study

Aims and objectives: To reveal meanings of family members' lived experiences when a loved one undergoes an interhospital intensive care unit-to-unit transfer. Background: Interhospital intensive care unit-to-unit transfers take place between different hospitals and their respective intensive care units (ICUs). These types of transfers are an increasing phenomenon but are sparsely studied from the

Orthogonal P-wave morphology, conventional P-wave indices, and the risk of atrial fibrillation in the general population using data from the Finnish Hospital Discharge Register

AIMS: Identifying subjects at high and low risk of atrial fibrillation (AF) is of interest. This study aims to assess the risk of AF associated with electrocardiographic (ECG) markers linked to atrial fibrosis: P-wave prolongation, 3rd-degree interatrial block, P-terminal force in lead V1, and orthogonal P-wave morphology. METHODS AND RESULTS: P-wave parameters were assessed in a representative Fi

Differentiable fixed-rank regularisation using bilinear parameterisation

Low rank structures are present in many applications of computer vision and machine learning. A popular approach consists of explicitly parameterising the set or matrices with sought rank, leading to a bilinear factorisation, reducing the problem to find the bilinear factors. While such an approach can be efficiently implemented using second-order methods, such as Levenberg-Marquardt (LM) or Varia

RIFM fragrance ingredient safety assessment, ethyl (E)hex-3-enoate, CAS registry number 26553-46-8

The existing information supports the use of this material as described in this safety assessment. Ethyl (E)hex-3-enoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog methyl 3-hexenoate (CAS # 2396-78-3) show that ethyl (E)hex-3-e

Lessons from the Swedish experience with negative central bank rates.

Negative interest rates were once seen as impossible outside the realm of economic theory. However, several central banks have recently adopted negative policy rates. The Federal Reserve is coming under increasing pressure to follow suit in the wake of the coronavirus crisis. This paper investigates the actual effects of negative interest rates using the Swedish experience from 2015 to 2019. The S

Ensembles of ecosystem service models can improve accuracy and indicate uncertainty

Many ecosystem services (ES) models exist to support sustainable development decisions. However, most ES studies use only a single modelling framework and, because of a lack of validation data, rarely assess model accuracy for the study area. In line with other research themes which have high model uncertainty, such as climate change, ensembles of ES models may better serve decision-makers by prov

Survival and prognostic factors after transplantation, resection and ablation in a national cohort of early hepatocellular carcinoma

Background: In patients with early hepatocellular cancer (HCC) and preserved liver function, the choice between transplantation, resection and ablation and which factors to consider is not obvious and guidelines differ. In this national cohort study, we aimed to compare posttreatment survival in patients fulfilling predefined criteria, and to analyse preoperative risk factors that could influence

Of pipe dreams and fossil fools : Advancing Canadian fossil fuel hegemony through the Trans Mountain pipeline

This article uses the Trans Mountain pipeline expansion project as a Canadian case study to critically examine and showcase one instance of the hegemony of fossil fuels in the era of global heating. The present Canadian federal government, under the leadership of Liberal Prime Minister Justin Trudeau, is seeking to simultaneously position itself as a global climate leader while supporting the expl

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

We investigated type 2 diabetes (T2D) genetic susceptibility via multi-ancestry meta-analysis of 228,499 cases and 1,178,783 controls in the Million Veteran Program (MVP), DIAMANTE, Biobank Japan and other studies. We report 568 associations, including 286 autosomal, 7 X-chromosomal and 25 identified in ancestry-specific analyses that were previously unreported. Transcriptome-wide association anal

Plasma insulin-like growth factor binding protein 1 in pulmonary arterial hypertension

Background: Beside the pulmonary vasoconstriction observed in pulmonary arterial hypertension (PAH), severe proliferative and antiapoptotic cellular phenotypes result in vascular remodelling. Many recent findings indicate similarities between PAH and tumour pathology. For instance, insulin-like growth factor (IGF)-1 signalling, which is known to promote tumour development, is implicated in PAH. Hi