Background: Non-alcoholic fatty liver disease has been associated with increased mRNA expression of FADS2 in the liver and estimated activity of delta-6 desaturase in serum, encoded by the FADS2 gene. Since DNA methylation in the FADS1/2/3 gene cluster has been previously linked with genetic variants and desaturase activities, we now aimed to discover factors regulating DNA methylation of the CpG

A single crystalline InSb nanosheet is an emerging planar semiconductor material with potential applications in electronics, infrared optoelectronics, spintronics, and topological quantum computing. Here, we report on the realization of a quantum dot device from a single crystalline InSb nanosheet grown by molecular-beam epitaxy. The device is fabricated from the nanosheet on a Si/SiO2 substrate,

Although botulinum neurotoxin serotype A (BoNT/A) products are common treatments for various disorders, there is only one commercial BoNT/B product, whose low potency, likely stemming from low affinity toward its human receptor synaptotagmin 2 (hSyt2), has limited its therapeutic usefulness. We express and characterize two full-length recombinant BoNT/B1 proteins containing designed mutations E119

An important question for video game research is how to characterize the video game experience. One common view emphasizes that players are cognitively able to operate with the game world as the experiential point of reference leading to states of "immersion, "spatial presence", or "engagement". A different view is that the player is also embodied and situated in the actual world, entailing that t

An in-cycle closed-loop combustion controller is proposed in this paper. The controller uses a pilot-main injection scheme where the cycle-individual properties of the pilot combustion are estimated by in-cylinder pressure measurements, and used to predict their effect on the heat release shape of the main combustion. The prediction is used to obtain the optimal main SOI that gives the Maximum Rea

Αν και η αρχαία ελληνική αποτελούσε βασικό μάθημα στο Πανεπιστήμιο Lund από την αρχή της λειτουργίας του, η διδασκαλία της Νέας Ελληνικής ξεκίνησε το 1957 υπό την επίδραση του αυξανόμενου ενδιαφέροντος για τη νεοελληνική λογοτεχνία και της ανάγκης εκπαίδευσης των Σουηδών αρχαιολόγων με αντικείμενο έρευνας την Ελλάδα. Το Τμήμα Νεοελληνικών Σπουδών του Πανεπιστημίου Lund, έχοντας πλέον αυτονομηθεί α

Objective: Glycoproteomics is an emerging subfield of proteomics. Tumor-specific variations in protein glycosylation might be potential targets for the development of new cancer diagnostics. Here, we performed high-throughput screening and targeted verification of glycome alterations in serum samples from patients with pancreatic cancer and the precancerous lesion intraductal papillary mucinous ne

Ernst Norlinds stora betydelse för Birger Sjöberg beskrivs. Norlind betydde mycket för debuten hos Bonniers, för studentaftonen i Lund 1923 och för bekantskapen med Poul Bjerres psykoanalytiska teori.

This paper conducts an inductive case study to understand how the opportunity creation process leads to integration. It examines four cases of immigrant entrepreneurs of Cameroonian, Lebanese, Mexican and Assyrian origins who founded their businesses in Sweden. The study relies on process-oriented theory building and develops an inductive model of integration as an opportunity creation process. Th

The crystalline lens of a vertebrate eye is a gradient-index lens and grows throughout life by addition of new lens fiber cells in the periphery. In fish, the growing ball-shaped lens maintains sophisticated optical properties throughout life by maintaining the distribution of refractive index relative to the increasing radius of the lens. During this process, the central fibers must increase refr

Objective: To investigate whether inverse probability of participation weighting (IPPW) using register data on sociodemographic and disease history variables can improve external validity in a cohort study with selective participation. Study Design and Setting: We fitted various IPPW models by logistic regression using register data for the participants (n = 1,111) and nonparticipants (n = 1,132)

Infantile hypertrophic pyloric stenosis (IHPS) is a disorder of young infants with a population incidence of ∼2/1000 live births, caused by hypertrophy of the pyloric sphincter smooth muscle. Reported genetic loci associated with IHPS explain only a minor proportion of IHPS risk. To identify new risk loci, we carried out a genome-wide meta-analysis on 1395 surgery-confirmed cases and 4438 controls

Neck-banded Greylag Geese Anser anser from a population breeding in southwest Scania, southern Sweden, were studied to assess changes in the breeding population and breeding performance during 1984–2013. The population increased ten-fold during this period, only to decrease again in the later years of the study. Greylag Geese arrived on the breeding grounds about 3–4 weeks earlier by 2007–2009 com

Neuropsychiatric symptoms (NPS) are increasingly recognized as a core element of Alzheimer's disease (AD); however, clinicians still consider AD primarily as a cognitive disorder. We describe a case in which the underrecognition of NPS as part of AD resulted in substantial delay of an AD diagnosis, a wrong psychiatric diagnosis, and the organization of inappropriate care. The aim of this paper is

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the single most common cause of vestibular vertigo and is characterised by short episodes of rotational vertigo precipitated by changes in head positions like lying down or turning in bed. OBJECTIVE: This study aims to assess useful questions when suspecting benign paroxysmal positional vertigo (BPPV) caused dizziness as well as identifyin